Acquired carnitine abnormalities in critically ill children

In order to characterize the role of carnitine during metabolic stress, we prospectively determined carnitine profiles in plasma and urine on admission, days 2, 5, 10 and 15, among 28 critically ill children free of any known conditions associated with secondary carnitine deficiency. More than 25% of plasma and 50% of urinary carnitine measurements were abnormal; 96% (27/28) of patients displayed on at least one occasion an abnormal [< -2 SD or > +2 SD] carnitine value in plasma. Three children had extremely low [< 10 micromol/l] free carnitine (FC) levels in plasma. Plasma esterified and FC levels on admission were not related to the risk of mortality [PRISM score], to muscle lysis [CK values], and to the caloric intake. Levels of FC and esterified carnitine in plasma were unrelated to those measured in urine. Conclusion: Abnormal plasma and urine carnitine measurements are frequently found in critically ill children; the biological significance of these perturbations remains unclear. Caution must be exercised before concluding that an abnormal carnitine value is indicative of an underlying hereditary metabolic disorder in this population.     

DESCRIPTION AND ANALYSIS OF TIMBER DRYING KINETICS

In this paper an experimental and semi-analytical technique is described that provides a method of estimating a macroscopic drying kinetics curve and internal moisture content profiles is described. Moisture gradients and the time evolution of these gradients are analysed as a function of the air drying parameters (dry-bulb, wet-bulb temperature and the velocity) and the product parameters (thickness and density). The material used as an illustration is a maritime-pine-wood.     

Analytical and numerical study of the densification of carbon/carbon composites by a film-boiling chemical vapor infiltration process

The film-boiling chemical vapor infiltration (CVI) process is a fast process developed for composite material fabrication, and especially carbon/carbon composites. In order to help define optimal conditions, a local 1D model has been developed to study the densification front which establishes itself during the processing of a carbon/carbon fibrous preform. The model features heat conduction, precursor gas diffusion, densification reactions and structural evolution of the porous medium. The effects of total mass flux, Thiele modulus, porous medium geometry on front behavior parameters such as width, velocity and residual porosity are presented as semi-analytical correlations. An existence criterion is produced, which involves a minimal heat flux. Comparison between process-scale experiments and simulation is then possible by inserting the semi-analytical results achieved in the local study of the front into a light numerical model involving the entire preform. The model has been validated with respect to previous experimental and numerical data.     

Invariance properties of RAMS and linear time

An operation on integers isLTTC if it is computable in linear time on a Turing machine (using the dyadic or binary representation of integers). AnLTTC-RAM (respectivelyI-RAM) is a RAM which only uses LTTC operations (respectively operations in the setI).The address-free time complexity measure of a RAM evaluates execution times using the logarithmic cost criterion but assumes that addressing operations are performed for free.     

AMOLED displays with transfer‐printed integrated circuits

Abstract— Small integrated circuits of crystalline silicon (chiplets) transfer‐printed onto a flat‐panel‐display substrate provide greatly improved electrical performance and uniformity in active‐matrix organic light‐emitting‐diode (OLED) displays. The integrated circuits are formed in high‐performance crystalline silicon using conventional photolithographic processes and then transfer‐printed onto a substrate using a stamp that transfers hundreds or thousands of chiplets at once. The chiplets are connected to an external controller and to pixel elements using conventional photolithographic substrate processing methods. Active‐matrix OLED (AMOLED) displays using transfer‐printed chiplets have good yields, excellent uniformity, and electrical performance and are thermally robust.     

Co-constructing with stakeholders a role-playing game to initiate collective management of erosive runoff risks at the watershed scale

Erosive runoff is a recurring problem and is a source of sometimes deadly muddy floods in the Pays de Caux (France). The risk results from a conjunction of natural factors and human activity. Efficient actions against runoff in agricultural watersheds are well known. However they are still difficult to implement as they require co-operation between stakeholders. Local actors thus need tools to help them understand the collective consequences of their individual decisions and help to initiate a process of negotiation between them. We decided to use a participatory approach called companion modelling (ComMod), and, in close collaboration with one of the first group of local stakeholders, to create a role-playing game (RPG) to facilitate negotiations on the future management of erosive runoff. This paper describes and discusses the development of the RPG and its use with other groups of local stakeholders within the framework of two game sessions organized by two different watershed management committees. During the joint construction step, stakeholders shared their viewpoints about the environment, agents, rules, and how to model runoff in preparation for the creation of the RPG. During the RPG sessions, two groups of eight players, including farmers, mayors and watershed advisors, were confronted with disastrous runoff in a fictive agricultural watershed. Results showed that they managed to reduce runoff by 20–50% by engaging a dialogue about grass strips, storage ponds and management of the intercrop period. However, further progress is still needed to better control runoff through the implementation of better agricultural practices because, during the RPG sessions, the watershed advisors did not encourage farmers to do so. Because of the complexity of management problems, results of jointly constructing the game and the RPG sessions showed that modelling and simulation can be a very useful way of accompanying the collective learning process. This new way of working was welcomed by the participants who expressed their interest in organizing further RPG sessions.     

Reasoning about fuzzy temporal information from the web: towards retrieval of historical events

When searching for information about historical events, queries are naturally formulated using temporal constraints. However, the structured temporal information needed to support such constraints is usually not available to information retrieval systems. Furthermore, the temporal boundaries of most historical events are inherently ill-defined, calling for suitable extensions of classical temporal reasoning frameworks. In this paper, we propose a framework based on a fuzzification of Allen’s Interval Algebra to cope with these issues. By using simple heuristic techniques to extract temporal information from web documents, we initially focus more on recall than on precision, relying on the subsequent application of a fuzzy temporal reasoner to improve the reliability of the extracted information, and to deal with conflicts that arise because of the vagueness of events. Experimental results indicate that a consistent and reliable knowledge base of fuzzy temporal relations can thus be obtained, which effectively allows us to target temporally constrained retrieval tasks.     

On a reflexivity-preserving family of cardinality-based fuzzy comparison measures

In this paper, we generalize and extend previous work on a triparametric family of cardinality-based fuzzy similarity measures. More specifically, we (i) generalize this family to a broader family of fuzzy comparison measures, (ii) summarize previously obtained results regarding this family and fill up a few gaps by adding some novel results, (iii) compare our parametric family with an already existing one, and (iv) elaborate on the ranking invariance between certain members of the presented triparametric family of cardinality-based fuzzy comparison measures.