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121.
Fabio Matta Piervincenzo Rizzo Vistasp M. Karbhari Francesco Lanza di Scalea 《Canadian Metallurgical Quarterly》2006,10(3):265-274
The use of adhesively bonded carbon fiber reinforced polymer (CFRP) laminates is increasingly being considered for the rehabilitation of metallic structures. The effective structural monitoring of steel/CFRP adhesive joints is of critical importance to assess the design service performance of the system, which ultimately depends on the bond damage tolerance at the load transfer regions. In the present study laboratory static and fatigue tests were conducted on steel/CFRP skin doubler and double strap joint specimens, which were monitored using the acoustic emission (AE) technique. The characteristics of the AE signals were correlated with the mechanical response of the samples, in order to understand the AE response associated with the accumulation of bond damage. One-dimensional source location was also performed to examine the initiation and the development of the disbond. The results show that AE parameter-based analysis is an effective nondestructive evaluation tool for bond damage detection and area location. 相似文献
122.
123.
Nesaretnam K Ambra R Selvaduray KR Radhakrishnan A Reimann K Razak G Virgili F 《Lipids》2004,39(5):459-467
It has recently been shown that tocotrienols are the components of vitamin E responsible for inhibiting the growth of human
breast cancer cells in vitro, through an estrogen-independent mechanism. Although tocotrienols act on cell proliferation in a dose-dependent manner and
can induce programmed cell death, no specific gene regulation has yet been identified. To investigate the molecular basis
of the effect of tocotrienols, we injected MCF-7 breast cancer cells into athymic nude mice. Mice were fed orally with 1 mg/d
of tocotrienol-rich fraction (TRF) for 20 wk. At end of the 20 wk, there was a significant delay in the onset, incidence,
and size of the tumors in nude mice supplemented with TRF compared with the controls. At autopsy, the tumor tissue was excised
and analyzed for gene expression by means of a cDNA array technique. Thirty out of 1176 genes were significantly affected.
Ten genes were down-regulated and 20 genes up-regulated with respect to untreated animals, and some genes in particular were
involved in regulating the immune system and its function. The expression of the interferon-inducible transmembrane protein-1
gene was significantly up-regulated in tumors excised from TRF-treated animals compared with control mice. Within the group
of genes related to the immune system, we also found that the CD59 glycoprotein precursor gene was up-regulated. Among the
functional class of intracellular transducers/effectors/modulators, the c-myc gene was significantly down-regulated in tumors
by TRF treatment. Our observations indicate that TRF supplementation significantly and specifically affects MCF-7 cell response
after tumor formation in vivo and therefore the host immune function. The observed effect on gene expression is possibly exerted independently from the
antioxidant activity typical of this family of molecules. 相似文献
124.
A trust negotiation system for digital library Web services 总被引:1,自引:0,他引:1
Halvard?SkogsrudEmail author Boualem?Benatallah Fabio?Casati 《International Journal on Digital Libraries》2004,4(3):185-207
A scalable approach to trust negotiation is required in digital library (DL) environments that have large and dynamic user populations. In this paper we introduce Trust-Serv, a model-driven trust negotiation framework for Web services, and show how it can be used to effectively handle trust negotiation in DLs. The framework employs a model for trust negotiation based on state machines, extended with security abstractions. High-level specifications expressed with the state-machine-based model are then translated into formats suitable for automating the trust negotiation process. The proposed framework also supports negotiation policy lifecycle management, an important trait in the dynamic environments that characterize DLs. In particular, we present a set of policy change operations that enable the dynamic evolution of negotiation policies without disrupting ongoing negotiations. The proposed approach has been implemented as a container-centric mechanism that is transparent to the DL and to the developers of DL Web services, simplifying DL development and management as well as enabling scalable deployments. 相似文献
125.
126.
Barbara?LeporiniEmail author Fabio?PaternòEmail author 《Universal Access in the Information Society》2004,3(1):57-70
The application of appropriate Web site design and evaluation methods helps to ensure more usable and accessible Web sites. While in the literature guidelines and evaluation methods for accessibility and usability are given and discussed separately, we aim at identifying the relationships between these two concepts, in particular considering usability criteria for accessible Web sites. In this work, we propose a set of such criteria targeted to improving the navigability for a specific group of disabled users, i.e., vision-impaired people. The identification of the eighteen criteria suggested herein was performed through empirical feedback, by which potential issues were identified. Subsequently, a systematic method was developed on the basis of the analysis of potential solutions, resulting in a classification of the criteria according to usability aspects. Some example applications of the proposed criteria to three existing public administration Web sites are discussed. 相似文献
127.
3D environments represent a great opportunity for universal access to information, as they offer an intuitive interaction paradigm, similar to what is experienced by humans in their everyday lives. In spite of that, several 3D interfaces are characterized by poor structures and are hard to navigate. This paper presents the multimodal concept of the Interaction Locus (IL) as a means to give structure to 3D scenes, helping the user to interact with and access information inside them. The concept was initially developed with particular reference to desktop virtual reality (2.5 D virtual reality), but it is general enough to be extended to other contexts, such as real 3D scenes. The final part of this work shows how the IL concept addresses the need for a unified authoring methodology, capable of allowing access to different target user groups from a variety of different devices. 相似文献
128.
Sharmila Subramaniam Vana Kalogeraki Dimitrios Gunopulos Fabio Casati Malu Castellanos Umeshwar Dayal Mehmet Sayal 《Information Systems》2007
Workflow management systems (WfMS) are widely used by business enterprises as tools for administrating, automating and scheduling the business process activities with the available resources. Since the control flow specifications of workflows are manually designed, they entail assumptions and errors, leading to inaccurate workflow models. Decision points, the XOR nodes in a workflow graph model, determine the path chosen toward completion of any process invocation. In this work, we show that positioning the decision points at their earliest points can improve process efficiency by decreasing their uncertainties and identifying redundant activities. We present novel techniques to discover the earliest positions by analyzing workflow logs and to transform the model graph. The experimental results show that the transformed model is more efficient with respect to its average execution time and uncertainty, when compared to the original model. 相似文献
129.
Gianpaolo Di Bona Alessandro Silvestri Fabio De Felice Antonio Forcina Antonella Petrillo 《Journal of Failure Analysis and Prevention》2016,16(6):1024-1037
The ever-increasing complexity of production systems, together with the need to obtain efficient processes with limited costs, has led companies to develop custom tools for process control and management. Even for risk assessment, the traditional models often are overcome by methods that are best suited to specific needs. In this context, the aim of this paper was to propose a new model, which we call the global safety improve risk assessment (G-SIRA). This model can classify risks and identify corrective actions that allow the best risk reduction at the lowest cost. The proposed model, which is based on improvements to previous research, uses the analytic hierarchy process approach to develop a valid and simple tool for risk management. The G-SIRA method has been tested in a real-world application, i.e., it was applied to all of the processes of a textile company, and the results were compared with those obtained from the classical approach failure mode, effects, and criticality analysis. The comparison clearly showed the effectiveness of the proposed model. 相似文献
130.
Gaia Vaglio Laurin Fabio Del Frate Luca Pasolli Claudia Notarnicola Leila Guerriero Riccardo Valentini 《International journal of remote sensing》2013,34(19):6898-6913
Natural vegetation monitoring in the alpine mountain range is a priority in the European Union in view of climate change effects. Many potential monitoring tools, based on advanced remote sensing sensors, are still not fully integrated in operational activities, such as those exploiting very high-resolution synthetic aperture radar (SAR) or light detection and ranging (lidar) data. Their testing is important for possible incorporation in routine monitoring and to increase the quantity and quality of environmental information. In this study the potential of ALOS PALSAR and RADARSAT-2 SAR scenes' synergic use for discrimination of different vegetation types was tested in an alpine heterogeneous and fragmented landscape. The integration of a lidar-based canopy height model (CHM) with SAR data was also tested. A SPOT image was used as a benchmark to evaluate the results obtained with different input data. Discrimination of vegetation types was performed with maximum likelihood classification and neural networks. Six tested data combinations obtained more than 85% overall accuracy, and the most complex input which integrates the two SARs with lidar CHM outperformed the result based on SPOT. Neural network algorithms provided the best results. This study highlights the advantages of integrating SAR sensors with lidar CHM for vegetation monitoring in a changing environment. 相似文献