Evaluation of the treatment of malaria using a 3-day regimen of quinine in Dakar

The paper provides a brief account and technical data of an AP-94-type device (a refractometer) for examination of ocular refraction, which operates in the infrared spectrum and allows a correct diagnosis to be promptly and qualitatively established and corrective means to be chosen for the patient. The results of clinical tests of the device are given.     

Impacts of ice cover on local scour around semi-circular bridge abutment简

The presence of ice cover in winter can significantly change the flow field around bridge abutments, which can also cause a different local scour pattern. To investigate the impacts of ice cover, results from a recent flume experiments were presented. Smooth and rough ice covers were created to investigate the impacts of ice cover roughness on the scour geometry around the semi-circular abutment. Three bed materials were used, with 50D s of 0.58 mm, 0.50 mm, 0.47 mm respectively. Scour volume and scour area were calculated. It was found that the maximum scour depth was located 75o inclined to the flume wall. Under rough ice cover, the scour area and scour depth were the largest. An empirical equation on the maximum scour depth was also developed.     

Strategies of performance self-monitoring in automotive production

Production in the automotive industry, based on assembly line work, is now characterized by lean manufacturing and customization. This results in greater flexibility and increased quality demands, including worker performance self-monitoring. The objectives of this study are to refine the concept of performance self-monitoring and to characterize the strategies developed by operators to achieve it. Data were collected based on the method of individual auto-confrontation, consisting of two steps: eleven assembly-line operators of a French automotive company were individually observed and video-taped while they were working; an interview then allowed each operator to discuss his/her activity based on the video-tape. This study expands the concept of performance self-monitoring by highlighting three types of strategies directly oriented toward quality: prevention, feedback control and control action strategies.     

压力反馈控制液压夯拔装置的实验研究

对液压夯拔装置的性能进行了分析，提出了通过立柱阻力适时调节系统的冲击压力，可实现冲击能和冲击频率的独立无级调节，并进行了实验研究。     

Stimuli controlling maladaptive consummatory behavior in infant dogs.

Studied stimulus condition, age and sex of Ss, and day of testing to determine their effect on the oral components of an abnormal behavioral state first observed in an operant conditioning situation and assumed to be a form of adjunctive behavior. A total of 60 beagle puppies, 4-8 and 15-17 days old, were intermittently stimulated to suck by a finger placed above or below the tongue or a milk-containing nipple placed above the tongue. Finger-below stimulation generally produced a response of the tongue sustained against the roof of the mouth, and finger above was correlated with a tongue position on the floor of the mouth. Findings are discussed in relation to pathological behavior on 3 levels of generality: response class, adjunctive behavior class, and etiology of pathological behavior. (26 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

High-pressure ion source combined with an in-axis ion trap mass spectrometer. 1. Instrumentation and applications

A new combination of a dual EI/CI ion source with a quadrupole ion trap mass spectrometer has been realized in order to efficiently produce negative ions in the reaction cell. Analysis of volatile compounds was performed under negative ion chemical ionization (NICI) during a reaction period where selected reactant negative ions, previously produced in the external ion source, were allowed to interact with molecules, introduced by hyphenated techniques such as gas chromatography. The O2*-, CH3O-, and Cl- reactant ions were used in this study to ensure specific ion/molecule interactions such as proton transfer, nucleophilic displacement, or charge exchange processes, respectively leading to even-electron species, i.e., deprotonated [M - H]- molecules, diagnostic [M - R]- ions, or odd-electron M*- molecular species. The reaction orientation depends on the thermochemistry of reactions within kinetic controls. First analytical results are presented here for the trace-level detection of several contaminants under NICI/Cl- conditions. Phosphorus-containing compounds (malathion, ethyl parathion, and methyl parathion as representative for pesticides) and nitro-containing compounds (2,4,6-trinitrotoluene for explosive material) have been chosen in order to explore the analytical ability of this promising instrumental coupling.     

Biologically-Directed Fractionation of Four Seasonal Extracts of Airborne Particulates and Related Chemical Studies

Ames assays (TA98) were applied toward assessing the mutagenic activities of extract fractions and subfractions of inhalable airborne particulate matter obtained in the manner of the earlier ATEOS study. Specifically, sequential cyclohexane, dichloromethane and acetone extracts of 24-hour samples were composited on a quarterly basis (ca 15 samples/quarter) and then fractionated using thin layer chromatography. For all four quarters the highest specific activities were associated with dichloromethane extracts and, specifically, its most polar fractions. Hydroxynitro-PAH are likely components in the dichloromethane extract. The cyclohexane extracts, containing PAH and nitro-PAH, were much less active. The acetone extracts had significant activity possibly associated with azaarenes and phenols. While PAH levels decreased in summer, nitro-PAH levels rose. No simple trend was observed for the PAH-quinones. 2-Nitropyren-1-ol, formed readily via solution photoxidation of 1-nitropyrene, does not appear to be formed under ambient atmospheric conditions. Preliminary FTIR, HPTLC and GC/MS results are described.     

Sources: The Center for the History of Psychology at the University of Akron.

The Center for the History of Psychology (CHP) was founded as the Archives of the History of Psychology (AHAP) in 1965 at The University of Akron in Akron, Ohio. In 2010, the Board of Trustees at The University of Akron approved the renaming of the Archives as the Center for the History of Psychology to reflect this increased scope of activities and offerings. The AHAP continues to operate as a unit with the larger Center. This article discusses the history of the CHP, its collections, research and accessibility initiatives, education and public programming initiatives, and the many ongoing projects and future plans for the CHP. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Survival of lactic acid bacteria from fermented milks in an in vitro digestion model exploiting sequential incubation in human gastric and duodenum juice

In the present study, the survival of 9 lactic acid bacteria (5 Lactococcus strains, 3 Lactobacillus strains, and 1 strain of Enterococcus hirae), was investigated in vitro under conditions similar to human digestion using human gastric and duodenal juices. The tolerance of the bacteria was also tested with traditional methods using acidic conditions and bile salts. The strains were subjected to a model digestive system comprising sequential incubation in human gastric and duodenal juices, in a 2-step digestion assay at 37°C, simulating the human upper gastrointestinal tract with human gastric juices at pH 2.5 and human duodenal juices at pH 7. The bacterial strains were tested either as washed cells from culture media or in fermented milk. The initial in vitro testing in acid and bile salts showed that Lactobacillus strains and the E. hirae strain displayed a significantly higher acid tolerance than the lactococci. The lactobacilli and the Enterococcus numbers increased, whereas the lactococci decreased at least 1 log during the bile salt treatment. The Lactobacillus strains showed the highest survival rate in the model digestive system when washed bacterial cultures were used with a minor log reduction, whereas the lactococci numbers were reduced by at least log 4. However, when using fermented milks in the model digestion system it was demonstrated that the Enterococcus strain and 2 strains of Lactococcus lactis ssp. cremoris benefited significantly from the presence of the fermented milk as food matrix, with log numbers >log 7 and 5, respectively, after digestion of the fermented milk. The analyses reported comprise a comprehensive in vitro testing regimen suitable for evaluation of the survival of candidate probiotic bacteria in human digestion as an initial prescreen to clinical trials.     

双吸离心泵泵站压力脉动与振动特性现场试验研究

双吸离心泵运行时,动静干涉会引起特定压力脉动,其频率为叶轮转频与叶片数相乘,即叶频。前期研究表明叶频压力脉动主要产生于压水室的隔舌区域,是引起水泵机组和泵房振动的重要激振源。为了揭示双吸离心泵系统压力脉动和振动特性的关系,开展了泵站压力脉动和振动特性的现场试验。通过在泵基础、出水管和泵房楼板位置布置振动传感器,同步测量了泵出口阀门不同开度下和泵启动开阀过程中的振动信号,借助时频分析方法开展了泵房振动信号的溯源分析。分析结果表明:在稳态工况中,水泵压力脉动和振动的相干性主要表现在转频、叶频及其倍频,且叶频压力脉动具有向上游衰减快,向下游衰减慢的特点;在启动工况中,水泵压水室压力脉动与基座(特别是垂直方向),甚至泵房出水侧楼板振动在叶频和转频处表现出相干性。根据现场测试结果认为,干室型双吸离心泵泵房在设计时,需要重点关注水泵叶频压力脉动作用下出水侧楼板等泵房结构的动力学响应问题。