The Impact of Grape Skin Bioactive Functionality Information on the Acceptability of Tea Infusions Made from Wine By-Products

ABSTRACT: The effect of information on the health benefits of bio-active compounds on the acceptability of 5 tea infusions made from grape skins generated from wine processing waste (from Vitis vinifera var. Pinot Noir and Pinot Gris) was investigated. Samples of tea infusions with natural additives (PNHGT25 and PGGT50) and without additives (control PN, control PG, and PNPG50) were evaluated by 45 in-home consumer panels (30 female, 15 male) before and after information on the health benefits of grape skins were provided. Information significantly increased the overall acceptability, overall aroma, flavor, and aftertaste of the infusions. The results obtained showed a clear tendency toward increased purchase intention (by 29%) when information on the health benefits of the tea infusion samples was provided to consumers. Interactions existed between gender/infusion samples and stage of information on the purchase intention. Females recorded a significant increase (by 53%) in purchase intention, whereas no change in the males' purchase intention was found after information was provided.     

Three-dimensional tomographic reconstruction of mesospheric airglow structures using two-station ground-based image measurements

A new methodology is presented to create two-dimensional (2D) and three-dimensional (3D) tomographic reconstructions of mesospheric airglow layer structure using two-station all-sky image measurements. A fanning technique is presented that produces a series of cross-sectional 2D reconstructions, which are combined to create a 3D mapping of the airglow volume. The imaging configuration is discussed and the inherent challenges of using limited-angle data in tomographic reconstructions have been analyzed using artificially generated imaging objects. An iterative reconstruction method, the partially constrained algebraic reconstruction technique (PCART), was used in conjunction with a priori information of the airglow emission profile to constrain the height of the imaged region, thereby reducing the indeterminacy of the inverse problem. Synthetic projection data were acquired from the imaging objects and the forward problem to validate the tomographic method and to demonstrate the ability of this technique to accurately reconstruct information using only two ground-based sites. Reconstructions of the OH airglow layer were created using data recorded by all-sky CCD cameras located at Bear Lake Observatory, Utah, and at Star Valley, Wyoming, with an optimal site separation of ~100 km. The ability to extend powerful 2D and 3D tomographic methods to two-station ground-based measurements offers obvious practical advantages for new measurement programs. The importance and applications of mesospheric tomographic reconstructions in airglow studies, as well as the need for future measurements and continued development of techniques of this type, are discussed.     

On the adaptive real-time detection of fast-propagating network worms

We present two light-weight worm detection algorithms that offer significant advantages over fixed-threshold methods. The first algorithm, rate-based sequential hypothesis testing (RBS), aims at the large class of worms that attempts to quickly propagate, thus exhibiting abnormal levels of the rate at which hosts initiate connections to new destinations. The foundation of RBS derives from the theory of sequential hypothesis testing, the use of which for detecting randomly scanning hosts was first introduced by our previous work developing TRW (Jung et al. in Proceedings of the IEEE Symposium on Security and Privacy, 9–12 May 2004). The sequential hypothesis testing methodology enables us to engineer detectors to meet specific targets for false-positive and false-negative rates, rather than triggering when fixed thresholds are crossed. In this sense, the detectors that we introduce are truly adaptive. We then introduce RBS+TRW, an algorithm that combines fan-out rate (RBS) and probability of failure (TRW) of connections to new destinations. RBS+TRW provides a unified framework that at one end acts as pure RBS and at the other end as pure TRW. Selecting an operating point that includes both mechanisms extends RBS’s power in detecting worms that scan randomly selected IP addresses. Using four traces from three qualitatively different sites, we evaluate RBS and RBS+TRW in terms of false positives, false negatives, and detection speed, finding that RBS+TRW provides good detection of actual Code Red worm outbreaks that we caught in our trace as well as internal Web crawlers that we use as proxies for targeting worms. In doing so, RBS+TRW generates fewer than one false alarm per hour for wide range of parameter choices.     

Surface modification of Ti-6Al-4 V alloy for biomineralization and specific biological response: part II,alkaline phosphatase grafting

Titanium and its alloys are the most widespread materials for the realization of orthopaedic and dental implants due to their good mechanical properties and biocompatibility. Surface functionalization of biomaterials aimed to improve and quicken implant integration and tissue regeneration is an active research field. The opportunity to confer biological activity (ability to directly stimulate cells with proper biological signals) to the Ti6Al4 V alloy, previously modified to be bioactive from the inorganic point of view (apatite precipitation), was explored in this research work. The alkaline phosphatase (ALP) enzyme was grafted to metal surface via tresyl chloride activation, maintaining its activity. A synergistic effect between biological functionalization and inorganic bioactivity was observed.     

Effect of nicotine on 35% CO2-induced anxiety: A study in healthy volunteers.

Panic disorder and cigarette smoking co-occur at a rate that exceeds what would be expected by chance. Theoretically, cigarette smoking may (a) attenuate panicky symptoms via cognitive factors or pharmacological action, (b) contribute to the development of panic disorder, or (c) share an etiological vulnerability with panic. The present study was aimed at testing whether nicotine has a direct influence on laboratory-elicited panic. In a placebo-controlled, double-blind, randomized, cross-over study, 33 healthy nonsmokers underwent a 35% CO2 challenge after transdermal administration of a nicotine patch on one test day and a placebo patch on another test day. Physiological measures (blood pressure, heart rate) and rating scale scores (Panic Symptom List [PSL], Visual Analog Scale of Anxiety, State-Trait Anxiety Inventory) were assessed. Compared with the placebo condition, nicotine increased diastolic blood pressure (p < .1), heart rate (p < .001), and PSL scores (p < .005) prior to the CO2 challenge but did not affect responding to the CO2 challenge itself. Results are consistent with the notion that nicotine promotes autonomic activation. However, the present study did not provide direct evidence that nicotine elicits panic in healthy volunteers. Replication in a clinical sample is warranted.     

Bioactive glass-derived trabecular coating: a smart solution for enhancing osteointegration of prosthetic elements

In this work, the use of foam-like glass–ceramic scaffolds as trabecular coatings on ceramic prosthetic devices to enhance implant osteointegration is proposed. The feasibility of this innovative device was explored in a simplified, flat geometry: glass–ceramic scaffolds, prepared by polymeric sponge replication and mimicking the trabecular architecture of cancellous bone, were joined to alumina square substrates by a dense glass coating (interlayer). The role played by different formulations of starting glasses was examined, with particular care to the effect on the mechanical properties and bioactivity of the final coating. Microindentations at the coating/substrate interface and tensile tests were performed to evaluate the bonding strength between the sample’s components. In vitro bioactive behaviour was assessed by soaking in simulated body fluid and evaluating the apatite formation on the surface and inside the pores of the trabecular coating. The concepts disclosed in the present study can have a significant impact in the field of implantable devices, suggesting a valuable alternative to traditional, often invasive bone-prosthesis fixation.     

Bioactive glass and glass-ceramic orbital implants

This review focuses on the applications of bioactive glasses and glass-ceramics in the field of orbital implants for ocular surgery. This use is relatively novel and less popular compared to the applications in orthopedics and dentistry for the repair of bone and teeth. Recent studies have shown the suitability of bioactive glasses and glass-ceramics in contact with soft tissues for promoting additional effects associated to the release of therapeutic inorganic ions. Specifically, the angiogenic and antibacterial actions that may be elicited by selected glass compositions are highly appealing for the development of new-generation orbital implants, since improved vascularization and antiseptic properties are the key for a higher success rate of anophthalmic socket procedures. An overall picture of existing orbital implants based on bioactive glasses is here provided, and the further potential and open challenges for future research in this field are highlighted and discussed.     

Enhancement of cold fusion reaction rates

Although major controversy still remains as to the source of the excess thermal power output reported from diverse successful cold fusion calorimetry experiments, considerable independent evidence does exist that low-level, deuterium fueled, cold fusion reactions can occur based upon reported neutron and tritium measurements. Because the specific fusion power output may be very low in present cold fusion experiments, there are numerous features and conditions associated with cold fusion experiments which might enhance fusion reaction rates.The principal focus of attention in enhancing cold fusion reactions occurring in an electrolytic cell is the palladium cathode where deuterium is preferentially absorbed into the cathode. The cathode's physical, metallurgical, and chemical characteristics such as purity, lattice cell size and orientation, chemical and hydrodynamic properties, and its electrical surface conditions and prevailing reactions are known to be important for maximizing deuterium loading. Even the geometrical size and configuration of the cathode and the crystalline grain size and conditioning are apparently important. The composition, pH, flow of the electrolyte, electrolysis employing rapidly time varying electrical potential and current and very high pressure and low temperature operation may also enhance fusion reaction rates.