The relationship between scientists’ research performance and the degree of internationalization of their research

Policy makers, at various levels of governance, generally encourage the development of research collaboration. However the underlying determinants of collaboration are not completely clear. In particular, the literature lacks studies that, taking the individual researcher as the unit of analysis, attempt to understand if and to what extent the researcher’s scientific performance might impact on his/her degree of collaboration with foreign colleagues. The current work examines the international collaborations of Italian university researchers for the period 2001–2005, and puts them in relation to each individual’s research performance. The results of the investigation, which assumes co-authorship as proxy of research collaboration, show that both research productivity and average quality of output have positive effects on the degree of international collaboration achieved by a scientist.     

Disturbed Exploitation compact Differential Evolution for limited memory optimization problems

This paper proposes a novel and unconventional Memetic Computing approach for solving continuous optimization problems characterized by memory limitations. The proposed algorithm, unlike employing an explorative evolutionary framework and a set of local search algorithms, employs multiple exploitative search within the main framework and performs a multiple step global search by means of a randomized perturbation of the virtual population corresponding to a periodical randomization of the search for the exploitative operators. The proposed Memetic Computing approach is based on a populationless (compact) evolutionary framework which, instead of processing a population of solutions, handles its statistical model. This evolutionary framework is based on a Differential Evolution which cooperatively employs two exploitative search operators: the first is based on a standard Differential Evolution mutation and exponential crossover, and the second is the trigonometric mutation. These two search operators have an exploitative action on the algorithmic framework and thus contribute to the rapid convergence of the virtual population towards promising candidate solutions. The action of these search operators is counterbalanced by a periodical stochastic perturbation of the virtual population, which has the role of “disturbing” the excessively exploitative action of the framework and thus inhibits its premature convergence. The proposed algorithm, namely Disturbed Exploitation compact Differential Evolution, is a simple and memory-wise cheap structure that makes use of the Memetic Computing paradigm in order to solve complex optimization problems. The proposed approach has been tested on a set of various test problems and compared with state-of-the-art compact algorithms and with some modern population based meta-heuristics. Numerical results show that Disturbed Exploitation compact Differential Evolution significantly outperforms all the other compact algorithms present in literature and reaches a competitive performance with respect to modern population algorithms, including some memetic approaches and complex modern Differential Evolution based algorithms. In order to show the potential of the proposed approach in real-world applications, Disturbed Exploitation compact Differential Evolution has been implemented for performing the control of a space robot by simulating the implementation within the robot micro-controller. Numerical results show the superiority of the proposed algorithm with respect to other modern compact algorithms present in literature.     

Constrained scheduling of the inspection activities on semiconductor wafers grouped in families with sequence-dependent set-up times

The scheduling of families of semiconductor wafers within the inspection department of a company producing electronic devices is considered in this paper. Changing the family of wafers to be inspected by an inspection machine requires a sequence-dependent set-up time; furthermore, due to the limited space availability of the inspection area, the available interoperational buffer capacity between the inspection machines is finite. The objective of the scheduling is the maximization of inspection department productivity, measured through the sequence makespan. A permutational flowshop group-scheduling problem (GSP) with sequence-dependent set-up times and limited interoperational buffer capacity has been taken into account. A benchmark of process scenarios considering different numbers of inspection machines wafers codes and families to be inspected has been generated. A Genetic Algorithm is here proposed as an efficient tool to solve the investigated problem. A comparison with a tabu search and a Nawaz, Enscore, and Ham procedure improving the currently available scheduler tool within the inspection department has been performed on the benchmark of problems. Finally, the influence on line productivity due to the finite interoperational buffer capacity is investigated.     

The Role of Testosterone in the Elderly: What Do We Know?

Testosterone is the most important hormone in male health. Aging is characterized by testosterone deficiency due to decreasing testosterone levels associated with low testicular production, genetic factors, adiposity, and illness. Low testosterone levels in men are associated with sexual dysfunction (low sexual desire, erectile dysfunction), reduced skeletal muscle mass and strength, decreased bone mineral density, increased cardiovascular risk and alterations of the glycometabolic profile. Testosterone replacement therapy (TRT) shows several therapeutic effects while maintaining a good safety profile in hypogonadal men. TRT restores normal levels of serum testosterone in men, increasing libido and energy level and producing beneficial effects on bone density, strength and muscle as well as yielding cardioprotective effects. Nevertheless, TRT could be contraindicated in men with untreated prostate cancer, although poor findings are reported in the literature. In addition, different potential side effects, such as polycythemia, cardiac events and obstructive sleep apnea, should be monitored. The aim of our review is to provide an updated background regarding the pros and cons of TRT, evaluating its role and its clinical applicability in different domains.     

Cold groundwater temperatures and conductive heat flow in the Mt. Amiata geothermal area, Tuscany, Italy

The hydrogeochemical study of the cold springs present in the Mt. Amiata geothermal area, where the Bagnore and Piancastagnaio geothermal fields are situated, has defined the different shallow groundwater systems.The cold groundwater temperature of the volcanic phreatic aquifer is largely correlated with the geothermal heat flow. Through the analysis of the temperature of cold groundwaters, a possible method for geothermal prospection has been developed, supported by the results obtained in the studied area. Through the enthalpic balance of the aquifer and in agreement with available data, a geothermal flow of about 200 mW m^-2 has been calculated.     

MicroRNA Cross-Involvement in Acne Vulgaris and Hidradenitis Suppurativa: A Literature Review

Acne Vulgaris (AV) and Hidradenitis suppurativa (HS) are common chronic inflammatory skin conditions that affect the follicular units that often coexist or are involved in differential diagnoses. Inflammation in both these diseases may result from shared pathways, which may partially explain their frequent coexistence. MicroRNAs (miRNAs) are a class of endogenous, short, non-protein coding, gene-silencing or promoting RNAs that may promote various inflammatory diseases. This narrative review investigates the current knowledge regarding miRNAs and their link to AV and HS. The aim is to examine the role of these molecules in the pathogenesis of AV and HS and to identify possible common miRNAs that could explain the similar characteristics of these two diseases. Five miRNA (miR-155 miR-223-, miR-21, and miRNA-146a) levels were found to be altered in both HS and AV. These miRNAs are related to pathogenetic aspects common to both pathologies, such as the regulation of the innate immune response, regulation of the Th1/Th17 axis, and fibrosis processes that induce scar formation. This review provides a starting point for further studies aimed at investigating the role of miRNAs in AV and HS for their possible use as diagnostic-therapeutic targets.     

3D floor plan recovery from overlapping spherical images

Computational Visual Media - We present a novel approach to automatically recover, from a small set of partially overlapping spherical images, an indoor structure representation in terms of a 3D...