Beam search algorithms for the single machine total weighted tardiness scheduling problem with sequence-dependent setups

In this paper, we consider the single machine weighted tardiness scheduling problem with sequence-dependent setups. We present heuristic algorithms based on the beam search technique. These algorithms include classic beam search procedures, as well as the filtered and recovering variants. Previous beam search implementations use fixed beam and filter widths. We consider the usual fixed width algorithms, and develop new versions that use variable beam and filter widths.     

Artificial institutions: a model of institutional reality for open multiagent systems

Software agents’ ability to interact within different open systems, designed by different groups, presupposes an agreement on an unambiguous definition of a set of concepts, used to describe the context of the interaction and the communication language the agents can use. Agents’ interactions ought to allow for reliable expectations on the possible evolution of the system; however, in open systems interacting agents may not conform to predefined specifications. A possible solution is to define interaction environments including a normative component, with suitable rules to regulate the behaviour of agents. To tackle this problem we propose an application-independent metamodel of artificial institutions that can be used to define open multiagent systems. In our view an artificial institution is made up by an ontology that models the social context of the interaction, a set of authorizations to act on the institutional context, a set of linguistic conventions for the performance of institutional actions and a system of norms that are necessary to constrain the agents’ actions.     

A multi-scale template method for shape detection with bio-medical applications

In this paper we present a novel methodology based on non-parametric deformable prototype templates for reconstructing the outline of a shape from a degraded image. Our method is versatile and fast and has the potential to provide an automatic procedure for classifying pathologies. We test our approach on synthetic and real data from a variety of medical and biological applications. In these studies it is important to reconstruct accurately the shape of the object under investigation from very noisy data. Here we assume that we have some prior knowledge about the object outline represented by a prototype shape. Our procedure deforms this shape by means of non-affine transformations and the contour is reconstructed by minimizing a newly developed objective function that depends on the transformation parameters. We introduce an iterative template deformation procedure in which the scale of the deformation decreases as the algorithm proceeds. We compare our results with those from a Gaussian Mixture Model segmentation and two state-of-the-art Level Set methods. This comparison shows that the proposed procedure performs consistently well on both real and simulated data. As a by-product we develop a new filter that recovers the connectivity of a shape.

Magnebike: A magnetic wheeled robot with high mobility for inspecting complex‐shaped structures

This paper describes the Magnebike robot, a compact robot with two magnetic wheels in a motorbike arrangement, which is intended for inspecting the inner casing of ferromagnetic pipes with complex‐shaped structures. The locomotion concept is based on an adapted magnetic wheel unit integrating two lateral lever arms. These arms allow for slight lifting off the wheel in order to locally decrease the magnetic attraction force when passing concave edges, as well as laterally stabilizing the wheel unit. The robot has the main advantage of being compact (180 × 130 × 220 mm) and mechanically simple: it features only five active degrees of freedom (two driven wheels each equipped with an active lifter stabilizer and one steering unit). The paper presents in detail design and implementation issues that are specific to magnetic wheeled robots. Low‐level control functionalities are addressed because they are necessary to control the active system. The paper also focuses on characterizing and analyzing the implemented robot. The high mobility is shown through experimental results: the robot not only can climb vertical walls and follow circumferential paths inside pipe structures but it is also able to pass complex combinations of 90‐deg convex and concave ferromagnetic obstacles with almost any inclination regarding gravity. It requires only limited space to maneuver because turning on the spot around the rear wheel is possible. This high mobility enables the robot to access any location in the specified environment. Finally the paper analyzes the maximum payload for different types of environment complexities because this is a key feature for climbing robots and provides a security factor about the risk of falling and slipping. © 2009 Wiley Periodicals, Inc.     

Fuzzy motion control strategy for cooperation of multiple automated vehicles with passengers comfort

This paper considers motion control for a cooperative system of automated passenger vehicles. It develops a cooperative scheme based on a decentralized planning algorithm which considers the vehicles in an initial open chain configuration. In this scheme the trajectories are intersections-free, and each trajectory is planned independently of the others. To ensure the stabilization of each vehicle in the planned trajectory, a fuzzy closed loop motion control is presented, where, based on the properties of the Fuzzy maps, the Lyapunov’s stability of the motion errors is demonstrated for all the vehicles. Based on the ISO 2631-1 standard, the saturation property of the Fuzzy maps guarantees low values of longitudinal and lateral accelerations, to ensure comfort of the human body during the motion. The validity of this control algorithm is supported by simulation experiments.     

A systematic literature review on IoT-aware business process modeling views,requirements and notations

Software and Systems Modeling - The Internet of things has been adopted in several sectors both influencing how people work and enhancing organizations’ business processes. This resulted in...     

Simplified analytical models for compressed concrete columns confined by FRP and FRCM system

In order to consider the response of concrete columns confined by FRP and FRCM system, proper models have to be formulated. In this context the present paper shows a generalized criterion for the determination of the increase in strength, in ductility and in dissipated energy for varying corner radius ratio of the cross section and fiber volumetric ratio. The procedure is based on the best fitting of several experimental data and unlike the usual empirical approaches available in the literature, the proposed technique relates the confinement effectiveness to a single parameter representative of the relative stiffness between the original concrete core and the reinforcement system. Furthermore, the proposed analytical models overcomes the limit of many empirical or semi-empirical models given in the literature that are applicable only to specific cases. A comparison with same available models confirm the reliability of the proposed procedure.     

Sorafenib delivery nanoplatform based on superparamagnetic iron oxide nanoparticles magnetically targets hepatocellular carcinoma

Currently,sorafenib is the only systemic therapy capable of increasing overall survival of hepatocellular carcinoma patients.Unfortunately,its side effects,particularly its overall toxicity,limit the therapeutic response that can be achieved.Superparamagnetic iron oxide nanoparticles (SPIONs) are very attractive for drug delivery because they can be targeted to specific sites in the body through application of a magnetic field,thus improving intratumoral accumulation and reducing adverse effects.Here,nanoformulations based on polyethylene glycol modified phospholipid micelles,loaded with both SPIONs and sorafenib,were successfully prepared and thoroughly investigated by complementary techniques.This nanovector system provided effective drug delivery,had an average hydrodynamic diameter of about 125 nm,had good stability in aqueous medium,and allowed controlled drug loading.Magnetic analysis allowed accurate determination of the amount of SPIONs embedded in each micelle.An in vitro system was designed to test whether the SPION micelles can be efficiently held using a magnetic field under typical flow conditions found in the human liver.Human hepatocellular carcinoma (HepG2) cells were selected as an in vitro system to evaluate tumor cell targeting efficacy of the superparamagnetic micelles loaded with sorafenib.These experiments demonstrated that this delivery platform is able to enhance sorafenib's antitumor effectiveness by magnetic targeting.The magnetic nanovectors described here represent promising candidates for targeting specific hepatic tumor sites,where selective release of sorafenib can improve its efficacy and safety profile.