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121.
Giuseppe Grosso Stefano Marventano Justin Yang Agnieszka Micek Andrzej Pajak Luca Scalfi 《Critical reviews in food science and nutrition》2017,57(15):3218-3232
Many studies have reported that higher adherence to Mediterranean diet may decrease cardiovascular disease (CVD) incidence and mortality. We performed a meta-analysis to explore the association in prospective studies and randomized control trials (RCTs) between Mediterranean diet adherence and CVD incidence and mortality. The PubMed database was searched up to June 2014. A total of 17 studies were extracted and 11 qualified for the quantitative analysis. Individuals in the highest quantile of adherence to the diet had lower incidence [relative risk (RR): 0.76, 95% confidence intervals (CI): 0.68, 0.83] and mortality (RR: 0.76, 95% CI: 0.68, 0.83) from CVD compared to those least adherent. A significant reduction of risk was found also for coronary heart disease (CHD) (RR: 0.72, 95% CI: 0.60, 0.86), myocardial infarction (MI) (RR: 0.67; 95% CI: 0.54, 0.83), and stroke (RR: 0.76; 95% CI: 0.60, 0.96) incidence. Pooled analyses of individual components of the diet revealed that the protective effects of the diet appear to be most attributable to olive oil, fruits, vegetables, and legumes. An average reduced risk of 40% for the aforementioned outcomes has been retrieved when pooling results of RCTs. A Mediterranean dietary pattern is associated with lower risks of CVD incidence and mortality, including CHD and MI. The relative effects of specific food groups should be further investigated. 相似文献
122.
Two novel process variations aware, necessary and sufficient conditions suitable for implementation in CAD optimizers are proposed to check amplifiers stability. Case studies are presented, showing that the new criteria allow robust amplifier design, under variation of active device immittance parameters in pre‐specified rectangular regions, due to manufacturing tolerances. © 2012 Wiley Periodicals, Inc. Int J RF and Microwave CAE 23: 619–626, 2013. 相似文献
123.
124.
Andrea Ianni Denise Innosa Camillo Martino Lisa Grotta Francesca Bennato Giuseppe Martino 《Journal of dairy science》2019,102(4):2918-2927
Zinc represents an essential microelement for several biochemical mechanisms. The body's inability to store zinc necessarily requires a constant dietary supply to avoid alteration of physiological functions. The aim of the present study was to investigate the effect of dietary enrichment with zinc on chemical-nutritional and aromatic properties of milk and cheese. Thirty commercial dairy cows, balanced for parity, milk production, and days in milk, were randomly assigned to 2 groups. The control group was fed with a conventional complete diet (22 kg of dry matter/animal per day), whereas the experimental group received a daily zinc supplementation of 60 mg per kg of dry complete feed. During the experimental period, the milk yield was monitored and samples of milk and caciotta cheese were collected to obtain information about the chemical-nutritional composition and aromatic profile. Dietary zinc integration did not influence milk yield and composition, but induced a marked reduction of somatic cell count and improved the oxidative stability of ripened caciotta cheese. In both milk and cheese, the experimental group samples were characterized by a lower concentration of saturated fatty acids and an increase in oleic acid, vaccenic acid, and rumenic acid. The aromatic profile of dairy products was also positively affected by dietary zinc intake, with an increase in concentration of carboxylic acids, aldehydes, and esters. The present results suggest a positive role of zinc in improving animal health and nutraceutical properties of milk and corresponding cheese. Taking into account the analysis of volatile compounds, zinc dietary supplementation of dairy cows should contribute to the production of cheeses with interesting organoleptic properties, although more studies are necessary to confirm the consumer acceptability of these changes. 相似文献
125.
Assessment of intradialysis calcium mass balance by a single pool variable‐volume calcium kinetic model
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Salvatore di Filippo Fabio Carfagna Vincenzo la Milia Antonio Bellasi Giustina Casagrande Camilla Bianchi Domenico Vito Maria Laura Costantino Giuseppe Rombolà Claudio Minoretti Carlo Schönholzer Giuseppe Pontoriero Francesco Locatelli 《Hemodialysis international. International Symposium on Home Hemodialysis》2018,22(1):126-135
Introduction: A reliable method of intradialysis calcium mass balance quantification is far from been established. We herein investigated the use of a single‐pool variable‐volume Calcium kinetic model to assess calcium mass balance in chronic and stable dialysis patients. Methods: Thirty‐four patients on thrice‐weekly HD were studied during 240 dialysis sessions. All patients were dialyzed with a nominal total calcium concentration of 1.50 mmol/L. The main assumption of the model is that the calcium distribution volume is equal to the extracellular volume during dialysis. This hypothesis is assumed valid if measured and predicted end dialysis plasma water ionized calcium concentrations are equal. A difference between predicted and measured end‐dialysis ionized plasma water calcium concentration is a deviation on our main hypothesis, meaning that a substantial amount of calcium is exchanged between the extracellular volume and a nonmodeled compartment. Findings: The difference between predicted and measured values was 0.02 mmol/L (range ?0.08:0.16 mmol/L). With a mean ionized dialysate calcium concentration of 1.25 mmol/L, calcium mass balance was on average negative (mean ± SD ?0.84 ± 1.33 mmol, range ?5.42:2.75). Predialysis ionized plasma water concentration and total ultrafiltrate were the most important predictors of calcium mass balance. A significant mobilization of calcium from the extracellular pool to a nonmodeled pool was calculated in a group of patients. Discussion: The proposed single pool variable‐volume Calcium kinetic model is adequate for prediction and quantification of intradialysis calcium mass balance, it can evaluate the eventual calcium transfer outside the extracellular pool in clinical practice. 相似文献
126.
Pasquale Massimiliano Falcone Massimo Mozzon Natale Giuseppe Frega 《Food research international (Ottawa, Ont.)》2012,45(1):75-84
The Traditional Balsamic Vinegar of Modena (TBVM) is a high-valuable Italian specialty that, for reasons not yet fully explained, may undergo non-equilibrium degrading phenomena involving phase separation and flow arrest caused by solidification with or without crystalline order. TBVM was probed for its microstructure and composition as well as for its flow ability under low- and high shear limits. Results indicated vinegar concentration, temperature and viscosity as three independent variables affecting the extent of solidification in TBVM. Polymer-mediated mechanisms and diffusion-limited kinetics were hypothesized for structure development. Three main experimental evidences offered a convincing proof unifying all solidification phenomena observed in TBVM under the concept of colloidal jamming transition: (i) simultaneous presence of fractal-like aggregated colloids and polydispersed biopolymers; (ii) non-linear shear dependence above a critical level of vinegar concentration; (iii) a modified Krieger–Dougherty model satisfactorily described scaling behavior of relative viscosity accounting for the fractal dimension of jammed structure. Threshold for jamming in TBVM was defined in terms of critical concentration of the overall structure-active constituents (corresponding to 72°Bx and 40% w/w of the main sugars) and maximum resistance to the Newtonian flow (the onset for shear-thinning flow was achieved with a low-shear limiting viscosity of about 0.95 Pa·s). 相似文献
127.
Composite Web services (WS) can be seen as software systems designed according to workflow-based orchestration of building blocks or simpler WS. Each block has its own specifications concerning both functional and non-functional properties. While the characteristics of each block have a scope limited to its domain, the WS must guarantee service levels that are usually described by global end-to-end metrics. The problem of relating local to global objectives in WS orchestration is hard to approach. In this context, some WS components have to be deployed in distributed service oriented infrastructure mixing heterogeneous systems belonging to private and/or public providers. In this paper we propose a performance-driven technique for designing and deploying composite WS on heterogeneous service oriented infrastructure. Users having different requirements in terms of resource demands and performance objectives are considered. Several WS deployment alternatives, involving both physical and virtual resources provided by the infrastructure, are evaluated to identify the logical (workflow) and physical (deployment) configuration allowing to meet the requirements. In order to demonstrate the suitability of the proposed approach to the service oriented context, an example of a travel management WS is described and the optimal deployment of the components in a hybrid infrastructure is investigated. 相似文献
128.
Chiara Manneschi Paola Fanzio Elena Angeli Giuseppe Firpo Luca Ceseracciu Valentina Mussi Luca Repetto Ugo Valbusa 《Microfluidics and nanofluidics》2013,14(1-2):21-30
Peculiar transport phenomena appear at nanoscale, since surface effects strongly affect the behaviour of fluids. Electrostatic and steric interactions, capillary forces and entropic effects play a key role in the behaviour of fluids and biomolecules. Since these effects strongly depend on the size of the nanofluidic system, a careful characterization of the fluidic environment is necessary. Moreover, the possibility to dynamically modulate the size of nanochannels is very appealing in the field of biomolecule manipulation. Recently, we have developed a lab-on-chip made of poly(dimethylsiloxane) (PDMS). This polymeric device is based on a tuneable nanochannel able to dynamically change its dimension in order to fit the application of interest. In fact, a mechanical compression applied on the top of the elastomeric device squeezes the nanochannel, reducing the channel cross section and allowing a dynamical optimization of the nanostructures. In this paper, this squeezing process is fully characterized both numerically and experimentally. This analysis provides information on the reduction of the nanochannel dimensions induced by compression as a function of the work of adhesion and of the stiffness of the materials composing the device. Moreover, calculations demonstrate the possibility to predict the change of the nanochannel size and shape induced by the compression. The possibility to dynamically tune the channel size opens up new opportunities in biomolecular sensing or sieving and in the study of new hydrodynamics effects. 相似文献
129.
Giuseppe Marannano Francesco Parrinello Antonio Giallanza 《Journal of Mechanical Science and Technology》2016,30(3):1119-1127
The generation of permanent compressive stresses around the holes is recognized as a valuable mean to delay the onset and propagation of the defects and to extend the fatigue life of the mechanical components. In the work, a bilateral indentation process, performed on each side of the component, is widely used in order to create a residual circumferential stress field around the area to be drilled and that persists after the drilling operation. In order to evaluate the process parameters and to identify optimal geometric solutions, several static and fatigue tests are conducted on AW 6082-T6 aluminum alloy specimen where two holes are created. In particular, experimental tests on only drilled specimens (OD) and specimens subjected to Indentation process (IP) varying the indentation depth and the center-tocenter distance of the holes are performed. Several numerical analyses, conducted in ANSYS APDL environment with explicit solver, allow to determine the influence of the distance between two adjacent holes and the effect of the indentation depth on the residual stress distribution. 相似文献
130.
Giuseppe Ateniese Alfredo De Santis Anna Lisa Ferrara Barbara Masucci 《Journal of Cryptology》2012,25(2):243-270
A time-bound hierarchical key assignment scheme is a method to assign time-dependent encryption keys to a set of classes in a partially ordered hierarchy, in such a way
that each class can compute the keys of all classes lower down in the hierarchy, according to temporal constraints. 相似文献