An abbreviated form of the Wechsler Intelligence Scale for Children.

This study was done in an attempt to determine a valid short form of the Wechsler Intelligence Scale for Children for a clinical population of reading disability cases. The subject group included all those children between the ages of 9 and 12, inclusive, referred to the Child Study Center at George Peabody College for Teachers in 1960 and 1961 as possible reading disability cases. A four-subtest combination consisting of Similarities, Object Assembly, Arithmetic, and Picture Arrangement correlated .947 with Full Scale score. The addition of either Vocabulary or Picture Completion yielded a correlation of .959. Since there were more than twice as many boys as girls in the sample, the data were analyzed for sex differneces. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Authoring and Searching in Dynamically Growing Hypertext Databases

In this paper we show how an application in the domain of Office Information Systems can be modelled so that a dynamically growing database of hypertext documents is created and automatically extended, as well as easily searched. We propose a method for analyzing office applications which relies on a model based on statecharts to record the flow of documents within the system. A prototype implementation is described of a hypertext system to support the creation, storage and retrieval of documents associated to formal face to face meetings. Special features to be incorporated into hypertext systems aimed at supporting the storage and retrieval of office documents are also identified.     

α-Amylase Mediates Host Acceptance in the Braconid Parasitoid <Emphasis Type="Italic">Cotesia flavipes</Emphasis>

Foraging parasitoids use chemical signals in host recognition and selection processes. Although, the volatiles play a relevant role in the localization by parasitoids of their hosts feeding on plants, the host identification process for acceptance occurs mainly during contact between the parasitoid and its host where host products related to feeding activities, fecal pellets and oral secretions, play a crucial role. The purpose of this study was to identify the nature of the contact kairomone(s) that mediate the acceptance for oviposition of the parasitoid Cotesia flavipes Cameron (Hymenoptera, Braconidae), which was released in Kenya in 1993 to control the invasive crambid Chilo partellus (Swinhoe). Using host and non-hosts of C. flavipes, we showed that it is mainly the oral secretions of the larvae that harbour the active compound(s) that mediate host acceptance for oviposition by C. flavipes. Using an integration of behavioral observations and biochemical approaches, the active compound of the oral secretions was identified as an α-amylase. Using synthetized α-amylases from Drosophila melanogaster (an insect model for which syntheses of active and inactive α-amylases are available), we observed that the conformation of the enzyme rather than its catalytic site as well as its substrate and its degradation product is responsible for host acceptance and oviposition mediation of C. flavipes females. The results suggest that the α-amylase from oral secretions of the caterpillar host is a good candidate for an evolutionary solution to host acceptance for oviposition in C. flavipes.     

Foxp3 Silencing with Antisense Oligonucleotide Improves Immunogenicity of an Adjuvanted Recombinant Vaccine against Sporothrix schenckii

Background: In recent years, there has been great interest in developing molecular adjuvants based on antisense oligonucleotides (ASOs) targeting immunosuppressor pathways with inhibitory effects on regulatory T cells (Tregs) to improve immunogenicity and vaccine efficacy. We aim to evaluate the immunostimulating effect of 2′OMe phosphorothioated Foxp3-targeted ASO in an antifungal adjuvanted recombinant vaccine. Methods: The uptake kinetics of Foxp3 ASO, its cytotoxicity and its ability to deplete Tregs were evaluated in murine splenocytes in vitro. Groups of mice were vaccinated with recombinant enolase (Eno) of Sporothix schenckii in Montanide Gel 01 adjuvant alone or in combination with either 1 µg or 8 µg of Foxp3 ASO. The titers of antigen-specific antibody in serum samples from vaccinated mice (male C57BL/6) were determined by ELISA (enzyme-linked immunosorbent assay). Cultured splenocytes from each group were activated in vitro with Eno and the levels of IFN-γ and IL-12 were also measured by ELISA. The results showed that the anti-Eno antibody titer was significantly higher upon addition of 8 µM Foxp3 ASO in the vaccine formulation compared to the standard vaccine without ASO. In vitro and in vivo experiments suggest that Foxp3 ASO enhances specific immune responses by means of Treg depletion during vaccination. Conclusion: Foxp3 ASO significantly enhances immune responses against co-delivered adjuvanted recombinant Eno vaccine and it has the potential to improve vaccine immunogenicity.     

The Evolution of Sweden's Urban Sustainability Marketing Tool: A Comparative Study of Two Major International Events

In this article, some of the obstacles for translating urban imaginaries and urban sustainability concepts based on technological interventions are analyzed. This analysis is built on experiences from the World Urban Forum 7 in Medellín, Colombia held in April 2014 and uses previous attempts to explore the production of imaginaries at play in the performance of SymbioCity, an urban development concept with a symbiosis tint created by the Swedish Trade Council. Through documenting the role of physical and non-physical messages from the Swedish delegation and its exhibition, along with numerous interviews with key actors at the conference and from the city's administration, an analysis of the current strategies used to promote the tool is provided. The claim that induced idealized urban futures sap energy and result in poor achievement of the goals is used to suggest that context and current conditions influence the ability to understand and adopt technological solutions. The conclusions are centered on the fact that SymbioCity, for the most part, is trying to sell products or services that are difficult to see and understand from the perspective of cities-customers, since most of these consist of invisible (i.e., energy), or hidden loops (i.e., waste and water). It is argued that there are contextual and historical conditions that are crucial for the decision to implement them that are, at least implicitly, expressed by the targeted cities-customers, and that the SymbioCity concept, or at least the way it is communicated in these fora, has undergone a change, in the sense that it has become more flexible and allowed for bottom-up considerations to enter the discourse.     

Interfacial tensions of industrial fluids from a molecular‐based square gradient theory

This work reports a procedure for predicting the interfacial tension (IFT) of pure fluids. It is based on scaling arguments applied to the influence parameter of the van der Waals theory of inhomogeneous fluids. The molecular model stems from the application of the square gradient theory to the SAFT‐VR Mie equation of state. The theory is validated against computer simulation results for homonuclear pearl‐necklace linear chains made up to six Mie (λ ? 6) beads with repulsive exponents spanning from λ = 8 to 44 by combining the theory with a corresponding states correlation to determine the intermolecular potential parameters. We provide a predictive tool to determine IFTs for a wide range of molecules including hydrocarbons, fluorocarbons, polar molecules, among others. The proposed methodology is tested against comparable existing correlations in the literature, proving to be vastly superior, exhibiting an average absolute deviation of 2.2%. © 2016 American Institute of Chemical Engineers AIChE J, 62: 1781–1794, 2016     

Scheduling of complex manufacturing systems with Petri nets and genetic algorithms: a case on plastic injection moulds

This paper introduces significant improvements on a previous published work that addresses complex production scheduling problems using Petri nets (PNs) and genetic algorithms (GAs). The PN model allows a formal representation of the manufacturing system and of the special constraints of this kind of system, while the GA generates a near-optimal schedule through the structure provided by the PN. The corresponding manufacturing system is associated with a flexible job shop environment with features such as the fabrication of multiple parts and precedence relationships between such parts and assembly operations, in which the objective is the minimisation of the total weighted tardiness. As part of the modelling stage, a mixed integer linear programming formulation is proposed for this framework. The fabrication of a chess mould in a Colombian company is used in two ways: to introduce a proposed normalisation operator that improves the results by reducing the search space of the GA and to illustrate the use of PN modelling the special aforementioned constraints as well as the encoding of the chromosome used by the GA. The proposed approach was tested on randomly generated instances, and their performance was measure against optimal solutions or solutions provided by algorithms presented in previous work. The results confirm the relevance of this approach to schedule such complex manufacturing systems.