Tetranorsesquiterpenoids as Attractants of Yucca Moths to Yucca Flowers

Journal of Chemical Ecology - The obligate pollination mutualism between Yucca and yucca moths is a classical example of coevolution. Oviposition and active pollination by female yucca moths occur...     

Privacy Preserving Geo-Linkage in the Big Urban Data Era

Big data technologies and a range of Government open data initiatives provide the basis for discovering new insights into cities; how they are planned, how they managed and the day-to-day challenges they face in health, transport and changing population profiles. The Australian Urban Research Infrastructure Network (AURIN – www.aurin.org.au) project is one example of such a big data initiative that is currently running across Australia. AURIN provides a single gateway providing online (live) programmatic access to over 2000 data sets from over 70 major and typically definitive data-driven organizations across federal and State government, across industry and across academia. However whilst open (public) data is useful to bring data-driven intelligence to cities, more often than not, it is the data that is not-publicly accessible that is essential to understand city challenges and needs. Such sensitive (unit-level) data has unique requirements on access and usage to meet the privacy and confidentiality demands of the associated organizations. In this paper we highlight a novel geo-privacy supporting solution implemented as part of the AURIN project that provides seamless and secure access to individual (unit-level) data from the Department of Health in Victoria. We illustrate this solution across a range of typical city challenges in localized contexts around Melbourne. We show how unit level data can be combined with other data in a privacy-protecting manner. Unlike other secure data access and usage solutions that have been developed/deployed, the AURIN solution allows any researcher to access and use the data in a manner that meets all of the associated privacy and confidentiality concerns, without obliging them to obtain ethical approval or any other hurdles that are normally put in place on access to and use of sensitive data. This provides a paradigm shift in secure access to sensitive data with geospatial content.     

User Preference for a Control-Based Reduced Processing Decision Support Interface

This study examined trainee crime-scene investigators' preference for, and accuracy in using, four different computer-based decision support interface designs, each of which incorporated a different reduced processing information acquisition strategy. The interfaces differed on the basis of the number of options that could be considered simultaneously and the level of control that could be exercised over the number and sequence in which feature values were accessed. Forty trainee investigators completed six decision scenarios in which they were asked to acquire information and formulate a decision by selecting one of three options. The study comprised two phases, the first of which involved familiarizing participants with each of the four interface designs and collecting performance and subjective data. The second phase involved trainees selecting one of the four interfaces to engage in a fifth and sixth decision scenario involving high or low levels of time-pressure. The results indicated that the “all options, full control” interface was the preferred option in the low time-pressure condition. Although the strategy remained the most frequently selected in the high time-pressure condition, this preference was not significant. It was concluded that the perceptions of difficulty and the degree of user control over information acquisition were more important than perceived efficiency in the selection of computer-based interface designs. The outcomes have implications for the design of decision support systems.     

Finding large 3-free sets I: The small n case

There has been much work on the following question: given n, how large can a subset of $\{1,\dots ,n\}$ be that has no arithmetic progressions of length 3. We call such sets 3-free. Most of the work has been asymptotic. In this paper we sketch applications of large 3-free sets, present techniques to find large 3-free sets of $\{1,\dots ,n\}$ for $n?250$, and give empirical results obtained by coding up those techniques. In the sequel we survey the known techniques for finding large 3-free sets of $\{1,\dots ,n\}$ for large n, discuss variants of them, and give empirical results obtained by coding up those techniques and variants.     

Rigor, rigor mortis, and conspiratorial views of depression research.

The authors reassert the need for methodological changes in depression research appearing in the Journal of Personality and Social Psychology and other personality and social psychology journals. In this rejoinder the authors update their earlier literature review (H. Tennen, J. Hall, & G. Affleck; see record 1995-31710-001) and respond to the commentaries by P C. Kendall and E. C. Flannery-Schroeder (see record 1995-31700-001) and G. Weary, J. A. Edwards, and J. A. Jacobson (see record 1995-31713-001). The authors notice that G. Weary et al.'s own findings demonstrate the need to change how depression is measured and participants are assigned to experimental groups. The authors also challenge G. Weary et al.'s contention that structured interviews are limited because they require interviewer judgments, and they urge personality and social psychologists to learn more about these interviews. Finally, G. Weary et al.'s suspicion that depression research guidelines reflect professional parochialism is disputed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Hyperprolactinemia in end‐stage renal disease and effects of frequent hemodialysis

Introduction: End‐stage renal disease is associated with elevations in circulating prolactin concentrations, but the association of prolactin concentrations with intermediate health outcomes and the effects of hemodialysis frequency on changes in serum prolactin have not been examined. Methods: The FHN Daily and Nocturnal Dialysis Trials compared the effects of conventional thrice weekly hemodialysis with in‐center daily hemodialysis (6 days/week) and nocturnal home hemodialysis (6 nights/week) over 12 months and obtained measures of health‐related quality of life, self‐reported physical function, mental health and cognition. Serum prolactin concentrations were measured at baseline and 12‐month follow‐up in 70% of the FHN Trial cohort to examine the associations among serum prolactin concentrations and physical, mental and cognitive function and the effects of hemodialysis frequency on serum prolactin. Findings: Among 177 Daily Trial and 60 Nocturnal Trial participants with baseline serum prolactin measurements, the median serum prolactin concentration was 65 ng/mL (25th–75th percentile 48–195 ng/mL) and 81% had serum prolactin concentrations >30 ng/mL. While serum prolactin was associated with sex (higher in women), we observed no association between baseline serum prolactin and age, dialysis vintage, and baseline measures of physical, mental and cognitive function. Furthermore, there was no significant effect of hemodialysis frequency on serum prolactin in either of the two trials. Discussion: Serum prolactin concentrations were elevated in the large majority of patients with ESRD, but were not associated with several measures of health status. Circulating prolactin levels also do not appear to decrease in response to more frequent hemodialysis over a one‐year period.     

Can twice weekly hemodialysis expand patient access under resource constraints?

The convention of prescribing hemodialysis on a thrice weekly schedule began empirically when it seemed that this frequency was convenient and likely to treat symptoms for a majority of patients. Later, when urea was identified as the main target and marker of clearance, studies supported the prevailing notion that thrice weekly dialysis provided appropriate clearance of urea. Today, national guidelines on hemodialysis from most countries recommend patients receive at least thrice weekly therapy. However, resource constraints in low‐ and middle‐income countries (LMIC) have resulted in a substantial proportion of patients using less frequent hemodialysis in these settings. Observational studies of patients on twice weekly dialysis show that twice weekly therapy has noninferior survival rates compared with thrice weekly therapy. In fact, models of urea clearance also show that twice weekly therapy can meet urea clearance “targets” if patients have significant residual function or if they follow a protein‐restricted diet, as may be common in LMIC. Greater reliance on twice weekly therapy, at least at the start of hemodialysis, therefore has potential to reduce health care costs and increase access to renal replacement therapy in low‐resource settings; however, randomized control trials are needed to better understand long‐term outcomes of twice versus thrice weekly therapy.     

Aeroelastic tailoring using lamination parameters

The aim of the present work is to passively reduce the induced drag of the rear wing of a Formula One car at high velocity through aeroelastic tailoring. The angle-of-attack of the rear wing is fixed and is determined by the required downforce needed to get around a turn. As a result, at higher velocity, the amount of downforce and related induced drag increases. The maximum speed on a straight part is thus reduced due to the increase in induced drag. A fibre reinforced composite torsion box with extension-shear coupled upper and lower skins is used leading to bending-torsion coupling. Three-dimensional static aeroelastic analysis is performed loosely coupling the Finite Element code Nastran and the Computational Fluid Dynamics panel code VSAERO using ModelCenter. A wing representative of Formula One rear wings is optimised for minimum induced drag using a response surface methodology. Results indicate that a substantial induced drag reduction is achievable while maintaining the desired downforce during low speed turns.