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181.
Gokhan Budan Khaled Hayatleh Denise Morrey Peter Ball Philip Shadbolt 《Analog Integrated Circuits and Signal Processing》2018,95(3):415-422
Intersection control has an important role in the management of urban traffic to ensure safety, high traffic flow and to prevent congestion. Recently, a growing body of literature has been reported on the theme of non-signalised intersection control in which traffic lights are replaced with intelligent road side units. Data from several studies suggest that non-signalised control could reduce vehicle delays and fuel consumption significantly whilst ensuring safety. However, there is little published data on the impact of the mixed driving behaviour with human-driven vehicles and autonomous vehicles. This paper investigates the emerging role of connectivity and vehicle autonomy in the context of traffic control under the mixed driving behaviour scenario. The concepts of vehicle-to-infrastructure (V2I) communications and multi-agent systems are central to achieving a robust and reliable traffic-light-free intersection control. Comprehensive computer simulation results on a four-way intersection indicate over 96% reduced average vehicle delay and 37% less fuel consumption with the non-signalised control solution compared to the traffic light control. The outcome of this study offers some important insights into enabling cooperation between vehicles and traffic infrastructure via V2I communications, in order to make more efficient real-time decisions about traffic conditions, whilst ensuring a higher degree of safety. 相似文献
182.
183.
Tapan Behl Ishnoor Kaur Aayush Sehgal Sukhbir Singh Saurabh Bhatia Ahmed Al-Harrasi Gokhan Zengin Adrian Gheorghe Bumbu Felicia Liana Andronie-Cioara Aurelia Cristina Nechifor Daniela Gitea Alexa Florina Bungau Mirela Marioara Toma Simona Gabriela Bungau 《International journal of molecular sciences》2021,22(13)
Progressive degeneration of neurons and aggravation of dopaminergic neurons in the substantia nigra pars compacta results in the loss of dopamine in the brain of Parkinson’s disease (PD) patients. Numerous therapies, exhibiting transient efficacy have been developed; however, they are mostly accompanied by side effects and limited reliability, therefore instigating the need to develop novel optimistic treatment targets. Significant therapeutic targets have been identified, namely: chaperones, protein Abelson, glucocerebrosidase-1, calcium, neuromelanin, ubiquitin-proteasome system, neuroinflammation, mitochondrial dysfunction, and the kynurenine pathway (KP). The role of KP and its metabolites and enzymes in PD, namely quinolinic acid (QUIN), kynurenic acid (KYNA), 3-hydroxykynurenine (3-HK), 3-hydroxyanthranillic acid (3-HAA), kunurenine-3-monooxygenase (KMO), etc. has been reported. The neurotoxic QUIN, N-methyl-D-aspartate (NMDA) receptor agonist, and neuroprotective KYNA—which antagonizes QUIN actions—primarily justify the Janus-faced role of KP in PD. Moreover, KP has been reported to play a biomarker role in PD detection. Therefore, the authors detail the neurotoxic, neuroprotective, and immunomodulatory neuroactive components, alongside the upstream and downstream metabolic pathways of KP, forming a basis for a therapeutic paradigm of the disease while recognizing KP as a potential biomarker in PD, thus facilitating the development of a suitable target in PD management. 相似文献
184.
Miriam Izzo Margot Jacquet Takayuki Fujiwara Ersan Harputlu Radosaw Mazur Piotr Wrbel Tomasz Gral C. Gokhan Unlu Kasim Ocakoglu Shinya Miyagishima Joanna Kargul 《International journal of molecular sciences》2021,22(16)
Here, we report the development of a novel photoactive biomolecular nanoarchitecture based on the genetically engineered extremophilic photosystem I (PSI) biophotocatalyst interfaced with a single layer graphene via pyrene-nitrilotriacetic acid self-assembled monolayer (SAM). For the oriented and stable immobilization of the PSI biophotocatalyst, an His6-tag was genetically engineered at the N-terminus of the stromal PsaD subunit of PSI, allowing for the preferential binding of this photoactive complex with its reducing side towards the graphene monolayer. This approach yielded a novel robust and ordered nanoarchitecture designed to generate an efficient direct electron transfer pathway between graphene, the metal redox center in the organic SAM and the photo-oxidized PSI biocatalyst. The nanosystem yielded an overall current output of 16.5 µA·cm−2 for the nickel- and 17.3 µA·cm−2 for the cobalt-based nanoassemblies, and was stable for at least 1 h of continuous standard illumination. The novel green nanosystem described in this work carries the high potential for future applications due to its robustness, highly ordered and simple architecture characterized by the high biophotocatalyst loading as well as simplicity of manufacturing. 相似文献
185.
Eisenberger Robert; Karagonlar Gokhan; Stinglhamber Florence; Neves Pedro; Becker Thomas E.; Gonzalez-Morales M. Gloria; Steiger-Mueller Meta 《Canadian Metallurgical Quarterly》2010,95(6):1085
In order to account for wide variation in the relationship between leader–member exchange and employees' affective organizational commitment, we propose a concept termed supervisor's organizational embodiment (SOE), which involves the extent to which employees identify their supervisor with the organization. With samples of 251 social service employees in the United States (Study 1) and 346 employees in multiple Portuguese organizations (Study 2), we found that as SOE increased, the association between leader–member exchange and affective organizational commitment became greater. This interaction carried through to in-role and extra-role performance. With regard to antecedents, we found in Study 1 that supervisor's self-reported identification with the organization increased supervisor's expression of positive statements about the organization, which in turn increased subordinates' SOE. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
186.
Omid Babaie Rizvandi Murat Gokhan Eskin Serhat Yesilyurt 《International Journal of Hydrogen Energy》2021,46(5):4378-4398
Operating the PEM fuel cell in the dead-ended anode mode reduces the overall cost and complexity of the system but causes a voltage loss and carbon corrosion in the cathode catalyst layer due to hydrogen starvation in the anode. Whereas allowing an ultra-low flowrate at the anode outlet offers a very high utilization of hydrogen and achieves a stable voltage transient. Here, a time-dependent pseudo-three-dimensional, two-phase, and non-isothermal model is developed to study the optimum bleeding rate, which maximizes the hydrogen utilization, achieves a stable cell voltage and avoids carbon corrosion, which is commonly observed when the bleed rate is set to zero, i.e. the dead-ended mode. The model is validated against the experimental data by comparing the polarization curves and cell voltage transients during the dead-ended anode operation of small experimental cells with serpentine and straight anode flow channels. Moreover, the effects of operating conditions on cell performance during the anode bleeding operation mode are investigated. Results demonstrate that the hydrogen utilization exceeds 99% in the anode-bleeding mode without hydrogen starvation, and the cell performance improves significantly for higher anode pressure, lower cell temperature, and lower relative humidity at the cathode inlet. Lastly, it is found that serpentine channels in the anode improve the uniformity of the distribution of hydrogen compared to straight and interdigitated channels in the anode-bleeding mode while the cathode flow field consists of serpentine channels. 相似文献
187.
Gokhan Kilic Shams A.M. Issa Erkan Ilik O. Kilicoglu U. Gokhan Issever R. El-Mallawany Bashar Issa H.O. Tekin 《Ceramics International》2021,47(5):6154-6168
To observe direct effect of samarium (III) oxide reinforcement on physical, thermal, optical, structural and nuclear radiation attenuation properties, a broad-range experimental and numerical investigations were performed with a group of novel borotellurite glasses. FTIR spectra of powdered samples were taken at 250-4000 cm-1. The transmittance and absorption characteristics, optical band gaps, and Urbach energies were measured. The glass transition temperatures, crystallization temperatures and melting temperature values of the samples were determined. Nuclear radiation shielding properties have been determined for gamma-ray, neutrons and heavy charged particles. The lowest transmittance and highest absorbance were reported for the TBVS1.5 sample with highest Sm2O3 additive. In addition, obtained results from the nuclear radiation shielding calculations have showed that TBVS1.5 sample has superior nuclear radiation shielding properties against gamma-ray, neutron and heavy charged particles. The increasing Sm2O3 additive has visibly improved the nuclear radiation attenuation properties by keeping other material properties within usable limits. 相似文献
188.
Design Methodology of a Hybrid Propulsion Driven Electric Powered Miniature Tailsitter Unmanned Aerial Vehicle 总被引:1,自引:0,他引:1
Contrary to the manned tailsitter aircraft concepts, which have been shelved and forgotten after mid 1960’s, the unmanned versions of these concepts have become popular. Since, tailsitter type UAVs combine both vertical takeoff and landing (VTOL) operation and relatively high speed cruise flight capabilities which provide manifest advantages over the other VTOL aircraft concepts, including helicopters and organic air vehicles (OAVs). However, there is no mini class tailsitter UAV with efficient high speed cruise flight capability. This paper presents the design methodology and optimization of ITU Tailsitter UAV concept with hybrid propulsion system approach to fill that gap. The initial design and analysis show the advantageous performance over other mini-class VTOL UAVs. 相似文献
189.
The effects of pre-strain and baking temperature on bake hardening behaviour of TWIP900 CR steel were investigated.The results reveal that the bake hardening process contributes to an increase in yield strength up to 65 MPa at the baking temperature of 200℃.The difference in yield strength between baking temperatures of 170 and 200℃is almost insignificant.It is clearly observed that baking at a high temperature does not result in a significant increase in yield strength.For a reasonable bake hardening,agood combination of pre-strain and baking temperature is necessary.Besides,the toughness of the material is found to decrease with increasing pre-strain. 相似文献