Application potential of bone marrow mesenchymal stem cell (BMSCs) based tissue-engineering for spinal cord defect repair in rat fetuses with spina bifida aperta

Spina bifida aperta are complex congenital malformations resulting from failure of fusion in the spinal neural tube during embryogenesis. Despite surgical repair of the defect, most patients who survive with spina bifida aperta have a multiple system handicap due to neuron deficiency of the defective spinal cord. Tissue engineering has emerged as a novel treatment for replacement of lost tissue. This study evaluated the prenatal surgical approach of transplanting a chitosan–gelatin scaffold seeded with bone marrow mesenchymal stem cells (BMSCs) in the healing the defective spinal cord of rat fetuses with retinoic acid induced spina bifida aperta. Scaffold characterisation revealed the porous structure, organic and amorphous content. This biomaterial promoted the adhesion, spreading and in vitro viability of the BMSCs. After transplantation of the scaffold combined with BMSCs, the defective region of spinal cord in rat fetuses with spina bifida aperta at E20 decreased obviously under stereomicroscopy, and the skin defect almost closed in many fetuses. The transplanted BMSCs in chitosan–gelatin scaffold survived, grew and expressed markers of neural stem cells and neurons in the defective spinal cord. In addition, the biomaterial presented high biocompatibility and slow biodegradation in vivo. In conclusion, prenatal transplantation of the scaffold combined with BMSCs could treat spinal cord defect in fetuses with spina bifida aperta by the regeneration of neurons and repairmen of defective region.     

Implementation of pseudo-nondiffracting beams by use of diffractive phase elements

We report the experimental implementation of pseudo-nondiffracting beams by use of diffractive phase elements (DPE's). Based on the conjugate-gradient method presented in J. Opt. Soc. Am. A 15, 144-151 (1998), these DPE's are designed and fabricated on a flat quartz substrate. The experimental results show that the performance of the fabricated DPE's is in good agreement with the theoretical prediction.     

Rotation-invariant and controllable space-variant optical correlation

We propose a method for designing a correlator for achieving rotation-invariant and controllable space-variant optical correlation. The design concept is based on a combination of fractional correlation and circular-harmonic decomposition of the reference object. The suggested method is described and analyzed in detail. Numerical simulations show that this new correlator might provide potential applications in practice.     

多目的IP传输设计实现

组播因其在点对多点传输方面拥有的优势,常被用于多媒体会议等应用。但是由于使用组播路由规模的限制,阻碍了在因特网推广组播技术的应用。首先对组播的原理作了分析,提出了具有组播特性的包含多个目的IP地址的IP传输设计,然后描述了一些关键问题,并讲解了具体设计和实现方法。     

Nanotextured superhydrophobic micromesh

A superhydrophobic micromesh covered with nanoprotrusions has been introduced and its applicability to a waterproof mobile phone speaker has been evaluated. The nanotextured superhydrophobic micromesh showed excellent water repellency, self-cleaning and waterproofing performances. In a waterproof speaker test using the fabricated nanotextured micromesh, the micromesh did not lose its waterproof function at 2 m water depth and did not form a remnant water film after being removed from the water. The packaged speaker showed almost the same sound quality before and after dipping at a 2 m water depth. These results demonstrate that the superhydrophobic nanotextured micromesh could be directly applicable for various products that need to resist water penetration, yet allow the transmission of gases and sound/light waves.     

Reachability determination in acyclic Petri nets by cell enumeration approach

Reachability is one of the most important behavioral properties of Petri nets. We propose in this paper a novel approach for solving the fundamental equation in the reachability analysis of acyclic Petri nets, which has been known to be NP-complete. More specifically, by adopting a revised version of the cell enumeration method for an arrangement of hyperplanes in discrete geometry, we develop an efficient solution scheme to identify firing count vector solution(s) to the fundamental equation on a bounded integer set, with a complexity bound of O((nu)^n−m), where n is the number of transitions, m is the number of places and u is the upper bound of the number of firings for all individual transitions.     

带微处理机的楔型流量计

介绍一种带压力、温度自动补偿的电远传楔型流量计,阐述了该流量计的工作原理、基本结构和性能特点。