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81.
Although cortico steroids are effective anti-inflammatory agents in ameliorating asthma symptoms and bronchial hperreactivity, their mechanism of action is unknown. Interleukin (IL)-5 is known to play a key role in regulating eosinophil proliferation and activation. Therefore, we examined the changes of IL-5 mRNA expressions in PBMC semi-quantitatively with RT-PCR as well as serum ECP levels and MCH-PC20 values in asthmatics before and after being treated with corticosteroids. The results revealed that there were significant decrease in the level of IL-5 mRNA and serum ECP concentration after therapy (P < 0.05) and there was remarkable improvement in the values of MCH-PC20 and FEV1% (P < 0.05). It was also found that the changes of serum ECP levels or MCH-PC20 values were accompanied by a reduction in IL-5 mRNA expression (r = 0.5426 or 0.4857, P < 0.05). These results suggested that the therapeutic effects of corticosteroids in asthma may result from modulation of IL-5 gene expression with consequent inhibition of eosinophil activation. 相似文献
82.
威海市污水处理深海排放工程是为改善其水域环境而建设的一英包括市区排水系统,污水预处理厂,输水管道和海洋放流管系统在内的完整而典型的工程,因此其工程设计扣的经验将会对同类项目的设计与工程建设有所借鉴。 相似文献
83.
Jin-Wei Shi Chi-Kuang Sun 《Lightwave Technology, Journal of》2002,20(11):1942-1950
We present the theory and design of a tapered line distributed photodetector (TLDP). In the previously demonstrated velocity-matched distributed photodetector (VMDP), high electrical bandwidth is achieved by proper termination in the input end to absorb reverse traveling waves, sacrificing one-half of the quantum efficiency. By utilizing the tapered line structure and phase matching between optical waves and microwaves in our analyzed structure, a traveling-wave photodetector is more realizable and ultrahigh bandwidth can be attained due to removal of the extra input dummy load that sacrifices one-half of the total quantum efficiency. To investigate the advantages of TLDP over VMDP, we calculate their electrical bandwidth performances by using an analytic photodistributed current model. We adopted low-temperature-grown (LTG) GaAs-based metal-semiconductor-metal (MSM) traveling-wave photodetectors as example unit active devices in the analytic bandwidth calculation for their high-speed and high-power performances. Both VMDP and TLDP in our simulation are assumed to be transferred onto glass substrates, which would achieve high microwave velocity/impedance and make radiation loss negligible. The simulated bandwidth of a properly designed LTG GaAs MSM TLDP is /spl sim/325 GHz, which is higher than the simulated bandwidth of the LTG GaAs MSM VMDP with an open-circuit input end (/spl sim/240 GHz) and is almost comparable to the simulated bandwidth of an input-terminated LTG GaAs MSM VMDP (/spl sim/330 GHz). This proposed method can be applied to the design of high-bandwidth distributed photodetectors for radio-frequency photonic systems and optoelectronic generation of high-power microwaves and millimeter waves. 相似文献
84.
85.
STEP-NC是由欧美提出的新的数控接口标准,目的是取代旧的数控标准ISO6983。本文首先分析了STEP-NC的两种应用标准:ISO14649(ARM)和STEPAP238(AIM),并且分析了Part21和Part28的应用领域及Part21文件格式和其中的信息产生方法。然後介绍了ST-Developer环境下ROSEC++颠库编程接口及其应用程序的早、晚编联方式,并且以此为基础设计了整个程序的编程流程,重点介绍了工艺规划设计。最后给出了在C++编程环境下利用ROSE库函数写入形成STEP AP238文件的方法。 相似文献
86.
Interface characteristics of carbon fibre reinforced copper matrix composites materials with various interface states and their effect on the flexural strength of composites have been studied. Interfacial states are mechanical bonding, dissolution bonding and reaction bonding. To a certain extent, raising the interfacial strength enables an increase in the flexural strength due to prevention of carbon fibre being pulled out under low stress during fracture process of composites. Raising the interfacial bondage strength, causes the brittleness of composites to increase; the fracture surface of composites is converted from a fibre pull-out model to a fibre even model. While strengthening the interface bondage, the extent of chemical reaction and dissolution at the interface must be controlled to avoid degrading the carbon fibre. 相似文献
88.
对汽油分馏塔的技术特点进行了分析,对急冷油系统的设计和汽油分馏塔的内件选择和设计进行了分析和讨论. 相似文献
89.
Biodegradable multiblock poloxamers (BMPs) with gel duration of 8 h to several weeks were prepared by varying their molecular weights from 4000 to 40 000 g mol?1. The molecular weight of the BMP was controlled by changing the poloxamer to coupling agent ratio. Assuming a micelle packing model of the BMP gel, as in the case of a poloxamer gel, the micelle properties and critical gel concentration of BMPs were investigated on the basis of the scaling concept. The findings suggest that the control of molecular weight by hydrolyzable groups can be a facile approach to optimize the gel properties for biomedical applications. Copyright © 2005 Society of Chemical Industry 相似文献
90.
Temperature and pH‐responsive interpenetrating polymer network (IPN) hydrogels, constructed with poly(methacrylic acid) (PMAA) and poly(vinyl alcohol) (PVA), by a sequential IPN method, were studied. The characterization of IPN hydrogels was investigated by Fourier‐transform infrared spectroscopy, differential scanning calorimetry (DSC) and swelling under various conditions. The IPN hydrogels exhibited relatively high swelling ratios, in the range 230–380 %, at 25 °C. The swelling ratios of the PMAA/PVA IPN hydrogels were pH and temperature dependent. DSC was used for the quantitative determination of the amounts of freezing and non‐freezing water. The amount of free water increased with increasing PMAA content in the IPN hydrogels. Copyright © 2004 Society of Chemical Industry 相似文献