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21.
Maciej Dabrowski Thomas Acton Hans van der Heijden 《Expert systems with applications》2012,39(9):8279-8287
This paper proposes a novel method for preference relaxation in online product search, which enables consumers to make quality choices without suffering from the commonly experienced information overload. In online shopping scenarios that involve multi-attribute choice tasks, it can be difficult for consumers to process the vast amounts of information available and to make satisfactory buying decisions. In such situations consumers are likely to eliminate potentially good choices early on, using hard-constraint filtering tools. Our approach uses edge sets to identify the alternatives on the soft boundary and the principle of alternative domination to suppress the alternatives on this boundary that are irrelevant. We demonstrate how our approach outperforms existing methods for product search in a set of simulations using two sets of 2650 car advertisements and 1813 digital cameras gathered from a popular online store. 相似文献
22.
A simple electrical model of the nerve axon is presented. The only non-linear element in the model is the sodium conductance, which is assumed to vary in a step-like way. This allows the propagation velocity for action potentials to be expressed analytically. The aftereffects from an action potential are generally slow. By considering them quasi-stationary, the velocity of a subsequent action potential can be calculated and compared with that of the first one. Considering the effects of afterpotential and afterconductance, it is shown that the theory adequately describes the variations in propagation velocity in the squid giant axon for action potentials separated by 3 ms to 14 ms. 相似文献
23.
Results from wear studies in repetitive impact sliding are described in this paper. The material pair studied consisted of steel CPM-10V (specimen) (where CPM denotes crucible particle metallurgy) and 17-4 precipitationhardened (PH) steel (counterface) with transverse sliding velocities of 4 and 8 m s?1. By means of scanning electron microscopy, energy-dispersive analysis of X-rays and X-ray diffraction methods it is shown that the wear is due to a material transport of the counterface 17-4 PH steel to the CPM-10V surface. In the wear process, a change in microhardness of the counterface substrate is apparent, and X-ray diffraction of debris confirms the presence of transformed metal. These products include γ-Fe together with trace amounts of α-Fe2O3; however, virtually no carbide from the CPM-10V steel was detected. 相似文献
24.
Swarna Mahadevan Kenelm Kwong Mingjie Lu Elizabeth Kelly Belal Chami Yevgeniy Romin Sho Fujisawa Katia Manova Malcolm A. S. Moore Hans Zoellner 《International journal of molecular sciences》2022,23(14)
We recently described cell-projection pumping as a mechanism transferring cytoplasm between cells. The uptake of fibroblast cytoplasm by co-cultured SAOS-2 osteosarcoma cells changes SAOS-2 morphology and increases cell migration and proliferation, as seen by single-cell tracking and in FACS separated SAOS-2 from co-cultures. Morphological changes in SAOS-2 seen by single cell tracking are consistent with previous observations in fixed monolayers of SAOS-2 co-cultures. Notably, earlier studies with fixed co-cultures were limited by the absence of a quantitative method for identifying sub-populations of co-cultured cells, or for quantitating transfer relative to control populations of SAOS-2 or fibroblasts cultured alone. We now overcome that limitation by a novel Cartesian plot analysis that identifies individual co-cultured cells as belonging to one of five distinct cell populations, and also gives numerical measure of similarity to control cell populations. We verified the utility of the method by first confirming the previously established relationship between SAOS-2 morphology and uptake of fibroblast contents, and also demonstrated similar effects in other cancer cell lines including from melanomas, and cancers of the ovary and colon. The method was extended to examine global DNA methylation, and while there was no clear effect on SAOS-2 DNA methylation, co-cultured fibroblasts had greatly reduced DNA methylation, similar to cancer associated fibroblasts. 相似文献
25.
W. Schreiber Schwaibold G. Steinhoff Beckel J. P. Bruno Roßmann Kanitz W. Ludorff Lars Erlandsen J. Großfeld Schormüller O. Windhausen Amelung H. Mohler Diemair Griebel Sachße E. Tornow W. Wodsak Bäurle C. Pyriki Zacher Jesser Reichard Schönfeld Pauletta Brüning Schloemer Hans Hawelka Kluge R. Grau H. Hanak Roßmann Egger Haevecker E. Dinslage Patzsch K. Müller K. Höll Steinbeck 《European Food Research and Technology》1943,86(5-6):453-568
26.
Kanitz Hans Hawelka Schormüller Schwaibold Griebel W. Schreiber Beckel Kortenhaus H. Wenzl Lars Erlandsen Klinc Patzsch Bäurle Diemair Adolf Hanak A. Lendle Pawletta Zacher R. Grau K. Höll Schloemer Jesser W. Wodsak Lindner Masling Haevecker Steinbeck J. Großfeld E. Tornow K. Müller W. Ludorff W. Hämmerle Willy Lindner Brüning O. Windhausen E. Dinslage C. Pyriki Reichard R. Strohecker Spitta Kluge Krzywanek R. Nitsche 《European Food Research and Technology》1942,84(3):230-288
27.
R. Grau Kanitz W. Schreiber Schwaibold Schormüller Rudolf Abderhalden Pawletta Willy Lindner Lars Erlandsen W. Ludorff W. Sutthoff Bäurle G. Steinhoff J. Großfeld Krumbholz Steuber Griebel Kluge Ingeborg Schmidt Steinbeck Beckel Reichard Brüning Haenel H. Mohler Lehnartz Hans Hawelka W. Hämmerle E. Dinslage Patzsch 《European Food Research and Technology》1941,81(6):508-576
28.
Bames H. J. Steinbeck W. Ludorff G. Mall Schormüller J. Ph. Br. Roßmann A. Lendle Schwaibold Albers W. Schreiber Rudolf Abderhalden Frey-Wyssling Hans Hawelka Bäurle W. Sutthoff Carls Griebel Kanitz Rietschel Griebel G. Stamm Körner-Hennig W. Leithe W. Hämmerle G. Steinhoff W. Wodsak Brüning Estler H. Hofmann Weber Mayser E. E. Bauke O. Windhausen Lars Erlandsen Kluge Kuckuck Haevecker Haevecker E. Dinslage I. Stahn Reichard K. Müller Hanak Kluge K. Höll Fr. Bartschat 《European Food Research and Technology》1940,79(3):272-335
29.
Hans Kreis und Emil Roth 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1913,26(1):38-42
Ohne ZusammenfassungMitteilung aus dem Laboratorium des Kantons-Chemikers Basel-Stadt. 相似文献
30.
Raymond Rosenbloom Igor Gavrish Anna E. Tseng Kerstin Seidel Shivraj M. Yabaji Hans P. Gertje Bertrand R. Huber Igor Kramnik Nicholas A. Crossland 《International journal of molecular sciences》2022,23(11)
Pulmonary infections caused by the group of nontuberculosis mycobacteria (NTM), Mycobacterium avium complex (MAC), are a growing public health concern with incidence and mortality steadily increasing globally. Granulomatous inflammation is the hallmark of MAC lung infection, yet reliable correlates of disease progression, susceptibility, and resolution are poorly defined. Unlike widely used inbred mouse strains, mice that carry the mutant allele at the genetic locus sst1 develop human-like pulmonary tuberculosis featuring well-organized caseating granulomas. We characterized pulmonary temporospatial outcomes of intranasal and left intrabronchial M. avium spp. hominissuis (M.av) induced pneumonia in B6.Sst1S mice, which carries the sst1 mutant allele. We utilized traditional semi-quantitative histomorphological evaluation, in combination with fluorescent multiplex immunohistochemistry (fmIHC), whole slide imaging, and quantitative digital image analysis. Followingintrabronchiolar infection with the laboratory M.av strain 101, the B6.Sst1S pulmonary lesions progressed 12–16 weeks post infection (wpi), with plateauing and/or resolving disease by 21 wpi. Caseating granulomas were not observed during the study. Disease progression from 12–16 wpi was associated with increased acid-fast bacilli, area of secondary granulomatous pneumonia lesions, and Arg1+ and double positive iNOS+/Arg1+ macrophages. Compared to B6 WT, at 16 wpi, B6.Sst1S lungs exhibited an increased area of acid-fast bacilli, larger secondary lesions with greater Arg1+ and double positive iNOS+/Arg1+ macrophages, and reduced T cell density. This morphomolecular analysis of histologic correlates of disease progression in B6.Sst1S could serve as a platform for assessment of medical countermeasures against NTM infection. 相似文献