Deformation behavior of isotactic polypropylene crystallized via a mesophase

The mechanical behavior of semicrystalline isotactic polypropylene (iPP) of different crystallinity, crystal morphology and superstructure was investigated by standard tensile stress–strain analysis, dynamic-mechanical analysis, and in situ observation of the deformation by atomic force microscopy (AFM). Emphasis is put on the comparison of the mechanical characteristics of specimens containing either non-isometric lamellae, being arranged in spherulites, or nodular isometric domains, which are not organized in a superstructure. The formation of lamellae/spherulites and of nodules was controlled by the conditions of crystallization. The replacement of cross-hatched monoclinic lamellae and a spherulitic superstructure by randomly arranged isometric nodules leads to a distinct increase of the ductility and toughness, even if the crystallinity is identical. The modulus of elasticity and the yield stress increase as expected with increasing crystallinity. Slightly lower values of Young’s modulus and yield strength are detected if samples contained non-lamellar crystals in a non-spherulitic superstructure, proving an effect of the crystal shape on the deformation behavior. For the first time, tensile deformation of semicrystalline iPP which contains nodular ordered domains instead of lamellae has been followed by in situ AFM.     

Sintering Kinetics of a MgAl2O4 Spinel Doped with LiF

The sintering kinetics of a pure magnesium aluminate spinel, MgAl₂O₄, and that doped with LiF were determined through the use of the master sintering curve technique developed by Su and Johnson. ²⁰ Powders with 0%, 0.5%, and 1.0% by mass LiF were densified in a vacuum hot press under a range of unaxial pressures. After the sintering mechanisms in each temperature and pressure regime were determined, an optimized vacuum hot-pressing schedule was formulated for spinel powders doped with 1.0% by mass of LiF. In addition to forming a transient liquid phase, the presence of LiF leads to the formation of oxygen vacancies that promote late-stage sintering in MgAl₂O₄.     

Development of a reliable grinding procedure for ceramic medical instruments

Surgical instruments have to meet strict requirements on functionality and stable performance. The functional properties of scalpels, for example, are mainly dependent on a precise cutting edge geometry and high blade sharpness. To achieve a reliable production of scalpels, it is necessary to establish a holistic understanding of the process chain as well as the interactions of all machining processes. An innovative zirconium oxide offers high toughness and high wear resistance, leading to its use in ophthalmic scalpels. A cooperative project has been conducted by two universities and two industrial partners, funded by the German Federal Ministry of Economics and Technology (BMWi).The project focuses particularly on the grinding process as a controlling factor for the scalpel’s functionality and sharpness. The complex process chain with various interactions of kinematics, vibrations and tool micro-topography was developed for high reliability and efficiency. The performance of in-machine dressing of diamond wheels with diamond form rollers was decisive for scalpel quality.     

Human DDX17 Unwinds Rift Valley Fever Virus Non-Coding RNAs

Rift Valley fever virus (RVFV) is a mosquito-transmitted virus from the Bunyaviridae family that causes high rates of mortality and morbidity in humans and ruminant animals. Previous studies indicated that DEAD-box helicase 17 (DDX17) restricts RVFV replication by recognizing two primary non-coding RNAs in the S-segment of the genome: the intergenic region (IGR) and 5′ non-coding region (NCR). However, we lack molecular insights into the direct binding of DDX17 with RVFV non-coding RNAs and information on the unwinding of both non-coding RNAs by DDX17. Therefore, we performed an extensive biophysical analysis of the DDX17 helicase domain (DDX17_135–555) and RVFV non-coding RNAs, IGR and 5’ NCR. The homogeneity studies using analytical ultracentrifugation indicated that DDX17_135–555, IGR, and 5’ NCR are pure. Next, we performed small-angle X-ray scattering (SAXS) experiments, which suggested that DDX17 and both RNAs are homogenous as well. SAXS analysis also demonstrated that DDX17 is globular to an extent, whereas the RNAs adopt an extended conformation in solution. Subsequently, microscale thermophoresis (MST) experiments were performed to investigate the direct binding of DDX17 to the non-coding RNAs. The MST experiments demonstrated that DDX17 binds with the IGR and 5’ NCR with a dissociation constant of 5.77 ± 0.15 µM and 9.85 ± 0.11 µM, respectively. As DDX17_135–555 is an RNA helicase, we next determined if it could unwind IGR and NCR. We developed a helicase assay using MST and fluorescently-labeled oligos, which suggested DDX17_135–555 can unwind both RNAs. Overall, our study provides direct evidence of DDX17_135–555 interacting with and unwinding RVFV non-coding regions.     

Simulation based model for tool life prediction in bevel gear cutting

Due to unpredictable tool life behavior in bevel gear cutting, unexpected production stops for tool changes occur. These lead to additional manufacturing costs. Because of its complexity, it is currently not possible to analyze the bevel gear cutting process sufficiently regarding tool life. This restriction leads to an iterative process design and determination of the ideal process parameters by using a trial-and-error approach. As a matter of fact, there is no concept to predict tool life in bevel gear cutting. Thus, a project has been initiated in order to develop a tool life model based on cutting simulation. This report presents the tool life model which combines a manufacturing simulation for bevel gear cutting with a regression model. The data of the regression model are determined by analogy trials. The combination of manufacturing simulation and regression model allows a local tool life prediction along the cutting edge.     

A Review on the Sintering and Microstructure Development of Transparent Spinel (MgAl2O4)

A review of the densification mechanisms and the microstructural development for transparent spinel made by free sintering and by hot pressing is given. The paper is divided into two main parts. The first part considers spinel without any sintering additives because there still is some controversy concerning the role of cation stoichiometry on sintering and grain growth. The second part discusses the role of the classic sintering aid, LiF, in processing transparent spinel. LiF is shown to have multiple behaviors: (1) it initially wets spinel and forms a liquid phase at relatively low temperatures, which affects early-stage densification and also grain growth; (2) upon cooling from intermediate temperatures, or even from higher temperatures if microstructure evolution (e.g., formation of closed porosity) prevents volatization, the LiF-containing liquid dewets and resides in isolated pockets; (3) LiF alters the cation stoichiometry, thereby enhancing diffusion via an increase in the concentration of oxygen vacancies; this affects both the densification rate and grain growth; and (4) it reacts with impurities in the system, thereby acting as a cleanser. For the production of transparent spinel, it is critical that LiF or associated reaction products not be retained as a secondary phase.     

Influence of process and geometry parameters on the surface layer state after roller burnishing of IN718

Highly stressed components of modern aircraft engines, like fan and compressor blades, have to satisfy stringent requirements regarding durability and reliability. The induction of compressive residual stresses and strain hardening in the surface layer of these components has proven as a very promising method to significantly increase their fatigue resistance. The required surface layer properties can be achieved by the roller burnishing process, which is characterised by high and deeply reaching compressive residual stresses, high strain hardening and excellent surface quality. In order to achieve a defined state of the surface layer, the determination of optimal process parameters for a given task still requires an elaborate experimental set-up and subsequent time-consuming and cost-extensive measurements. The development of well funded process knowledge about the correlation of the process parameters, the processed geometry and the surface layer state is the subject of this article.     

An Enantioselective Total Synthesis of (+)-Elenoic Acid and the Non-Natural Enantiomers of Tetrahydroalstonine,Aricine, and Reserpinine

A simple enantioselective synthesis of (+)epi-elenoic acid is reported and its transformation into (+)-elenoic acid is described. Well-established procedures transform these compounds into the antipodes of tetrahydroalstonine, aricine, and reserpinine.