Making Asset Investment Decisions for Wastewater Systems That Include Sustainability

Effective integrated water management is a key component of the World Water Vision and the way in which aspirations for water equity may be realized. Part of the vision includes the promotion of sustainability of water systems and full accountability for their interaction with other urban systems. One major problem is that “sustainability” remains an elusive concept, although those involved with the provision of urban wastewater systems now recognize that decisions involving asset investment should use the “triple bottom line” approach to society, the economy, and the environment. The Sustainable Water Industry Asset Resource Decisions project has devised a flexible and adaptable framework of decision support processes that can be used to include the principles of sustainability more effectively. Decision mapping conducted at the outset of the project has shown that only a narrow range of criteria currently influence the outcome of asset investment decisions. This paper addresses the concepts of sustainability assessment and presents two case studies that illustrate how multicriteria decision support systems can enhance the assessment of the relative sustainability of a range of options when decisions are being made about wastewater asset investment.     

Mutations That Affect the Surface Expression of TRPV6 Are Associated with the Upregulation of Serine Proteases in the Placenta of an Infant

Recently, we reported a case of an infant with neonatal severe under-mineralizing skeletal dysplasia caused by mutations within both alleles of the TRPV6 gene. One mutation results in an in frame stop codon (R₅₁₀stop) that leads to a truncated, nonfunctional TRPV6 channel, and the second in a point mutation (G₆₆₀R) that, surprisingly, does not affect the Ca²⁺ permeability of TRPV6. We mimicked the subunit composition of the unaffected heterozygous parent and child by coexpressing the TRPV6 G₆₆₀R and R₅₁₀stop mutants and combinations with wild type TRPV6. We show that both the G₆₆₀R and R₅₁₀stop mutant subunits are expressed and result in decreased calcium uptake, which is the result of the reduced abundancy of functional TRPV6 channels within the plasma membrane. We compared the proteomic profiles of a healthy placenta with that of the diseased infant and detected, exclusively in the latter two proteases, HTRA1 and cathepsin G. Our results implicate that the combination of the two mutant TRPV6 subunits, which are expressed in the placenta of the diseased child, is responsible for the decreased calcium uptake, which could explain the skeletal dysplasia. In addition, placental calcium deficiency also appears to be associated with an increase in the expression of proteases.     

Chronic in vivo nerve electrical recordings of Aplysia californica using a boron-doped polycrystalline diamond electrode

Custom diamond electrodes for in vivo, passive electrical nerve recording were developed and implanted in an intact, freely behaving Aplysia californica. A diamond electrode may have advantages for electrical recording because of its chemical stability, higher signal-to-noise ratio, and reduced biological fouling relative to traditional nerve-recording electrode materials. For example, thin stainless steel electrodes used for chronic extracellular recording in Aplysia typically last on the order of seven days in vivo. We have developed a first-generation diamond electrode with a flexible lead to withstand the complicated movements of Aplysia and to enable direct comparison with implanted stainless steel electrodes.Boron-doped polycrystalline diamond was grown onto tungsten wire substrates by hot filament chemical vapor deposition. The wires were pre-shaped into a hook (for nerve recording) or a loop (for a ground wire) and masked for selective growth on only 2–3 mm of the wire. After diamond growth, the uncoated portion of the wire substrates was removed and the intact diamond-coated hook or loop attached to a stainless steel electrical lead with conductive epoxy. After epoxy curing, these electrodes were insulated and implanted in the animal.The diamond and stainless steel electrodes were attached extracellularly to buccal nerve 2, a primary nerve for the feeding behavior of A. californica. The two electrodes were implanted adjacent to each other so that the recordings would be nearly synchronous. In vivo recordings were successfully obtained on a diamond hook electrode during a feeding behavior for up to 9 days after the implantation. The electrode remained intact for a total of 28 days in the animal and upon retrieval.     

Miscibility and properties of linear poly(l-lactide)/branched poly(l-lactide) copolyester blends

Polymer blends consisting of linear poly(l-lactide) (PLLA) and different proportions of dendritic PLLA-based copolyesters (hb-PLLA) characterized by different degrees of branching (DB) were obtained in melt. The solid-state properties of poly(l-lactide)s and their blends were investigated by differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), atomic force microscopy (AFM) and stress-strain measurements. DSC and DMA methods proved miscibility of PLLA/hb-PLLA blends for the studied composition range. AFM indicated that no phase separation occurs in PLLA/hb-PLLA blends and that PLLA and hb-PLLA cocrystallize in one single lamellae type. The mechanical characteristics of PLLA/hb-PLLA blends deteriorated with an increase of the DB and with changing blend composition. Susceptibility of the blends to biodegradation was studied by measuring the weight loss in two different biodegradation media. PLLA/hb-PLLA blends showed more pronounced hydrophilic character and higher susceptibility to biodegradation with an increase in the degree of branching.     

The effects of paints and moisture content on the indoor air emissions from pinewood (Pinus sylvestris) boards

The emissions of volatile organic compounds (VOCs) from building materials may significantly contribute to indoor air pollution, and VOCs have been associated with odor annoyance and adverse health effects. Wood materials together with coatings are commonly used indoors for furniture and large surfaces such as walls, floors, and ceilings. This leads to high surface-to-volume ratios, and therefore, these materials may participate remarkably to the VOC levels of indoor environment. We studied emissions of VOCs and carbonyl compounds from pinewood (Pinus sylvestris) boards of 10% and 16% moisture contents (MC) with three paints using small-scale test chambers (27 L). The emissions from uncoated pinewood and paints (on a glass substrate) were tested as references. The 28-day experiment showed that the VOC emissions from uncoated pinewood were lower from sample with 16% MC. Painted pinewood samples showed lower emissions compared to paints on glass substrate. Additionally, paints on 16% MC pinewood exhibited lower emissions than on drier 10% MC wood. The emissions from painted pinewood samples were dominated by paint-based compounds, but the share of wood-based compounds increased over time. However, we noticed differences between the paints, and wood-based emissions were clearly higher with the most permeable paint.     

Children's beliefs about intelligence and school performance.

The study was designed, first, to explore associations among children's beliefs about intelligence and effort, goal orientations, self-reported learning strategies, and academic achievement. Assessments of all variables were conducted twice over 1 school year on 319 children in Grades 3–6. Results indicate that the belief that intelligence is relatively fixed was associated with the beliefs that performance is relatively stable and that intelligence is global in its effects on performance. This set of beliefs was differentiated from the belief that effort has positive effects on intelligence and performance. Children's beliefs in intelligence as fixed and affecting performance were negatively associated with academic achievement, but a path analysis provided only modest support for the hypothesis that the effect of such beliefs would be mediated by a performance goal orientation and accompanying superficial learning strategies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Self-control game interventions for attention-deficit hyperactivity disorder.

Compared the effects of self-control training, using cognitive-behavioral game play (CB) and biofeedback game play (BF), on the behaviors of 58 male and 5 female 8–12 yr olds with Full Scale IQ of 90 or higher on the Wechsler Intelligence Scale for Children--Revised (WISC--R) and diagnosed with attention deficit hyperactivity disorder (ADHD). The experimental groups were compared to a control game group (GC), which received no self-control training. A 3?×?3 (treatment?×?time) factorial design with repeated measures, using IQ as a covariate, and multiple outcome criteria was employed comparing the groups. Findings support the hypothesis that self-control training by BF reduces a child's perception of his or her self-control problems, but the same does not generalize to parental report of self-control or behavioral measures. Hyperactivity, one of the cardinal symptoms of ADHD, was significantly decreased in GC. (PsycINFO Database Record (c) 2010 APA, all rights reserved)