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81.
In developing data‐driven models of complex real‐world systems, a common problem is how to select relevant inputs from a large set of measurements. If the observations of the outputs to be predicted by the model are scarce, which may be the case if the outputs are indices determined in toilsome laboratory tests, strict constraints have to be imposed on the number of model parameters. In neural network modelling, this limitation in practice also restricts the number of hidden nodes as well as the number of input variables, since the dimension of the weight vector strongly depends on these. This paper presents a systematic method for data‐driven modelling with feedforward layered neural networks, including a method for the selection of input variables. The method is illustrated on a problem from ironmaking industry, where sinter quality indices are predicted on the basis of raw material properties. Furthermore, an inversion technique of the resulting network models is proposed, where an optimization problem is solved to maximize the performance of the sintering operation by manipulating the inputs. 相似文献
82.
Larsson Henrik; Andershed Henrik; Lichtenstein Paul 《Canadian Metallurgical Quarterly》2006,115(2):221
The psychopathic personality can be conceptualized as three interrelated dimensions, (a) an interpersonal style of glibness, grandiosity, and manipulation; (b) an affective disposition of callousness, lack of empathy, and unemotionality; and (c) a behavioral/lifestyle dimension of impulsivity, need for stimulation, and irresponsibility, underpinning a higher order construct, psychopathic personality. The authors used a self-report questionnaire (The Youth Psychopathic Traits Inventory) to study the importance of genetic and environmental influences on psychopathic personality traits in a sample of 1,090 monozygotic and dizygotic twin pairs, aged 16-17 years. Results showed a strong genetic influence behind the higher order "psychopathic personality" factor, underpinned by the three psychopathic personality dimensions. Over and above the effects to the higher order factor, significant unique genetic influences were also found in the callous/unemotional and in the impulsive/irresponsible dimension, but not in the grandiose/manipulative dimension. The authors propose that this latent psychopathic personality factor is a meaningful target for future etiological research. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
83.
Stig Kildegrd Andersen Henrik Carlsen Per Grove Thomsen 《Simulation Modelling Practice and Theory》2006,14(8):1073
We present an approach for modelling unsteady, primarily one-dimensional, compressible flow. The conservation laws for mass, energy, and momentum are applied to a staggered mesh of control volumes and loss mechanisms are included directly as extra terms. Heat transfer, flow friction, and multidimensional effects are calculated using empirical correlations. Transformations of the conservation equations into new variables, artificial dissipation for dissipating acoustic phenomena, and an asymmetric interpolation method for minimising numerical diffusion and non physical temperature oscillations are presented. The capabilities of the approach are illustrated with an example solution and an experimental validation of a Stirling engine model. 相似文献
84.
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86.
In order to turn reliability prediction into a readily available tool, a system for computerized handling of failure rates was developed at FTL. This system, which is named RPP-1 (Reliability Program One) is presently covering data of electronic and electromechanical components. From a given list of components and data on stresses and working conditions, the failure rates are automatically searched, processed, and pooled in an assessment for an equipment. To make this possible, a number of decisions and judgements had to be taken regarding codes, formulas, models, bank structure, application factors, etc. This paper gives a summary of the FTL solutions for those basic questions. The system?actually a system of subprograms?has been developed at the Swedish Military Electronics Laboratory. The project was headed by the the author of this paper. 相似文献
87.
Iva Marija Toli?-Nørrelykke Kirstine Berg-Sørensen Henrik Flyvbjerg 《Computer Physics Communications》2004,159(3):225-240
Optical tweezers are used as force transducers in many types of experiments. The force they exert in a given experiment is known only after a calibration. Computer codes that calibrate optical tweezers with high precision and reliability in the (x,y)-plane orthogonal to the laser beam axis were written in MatLab (MathWorks Inc.) and are presented here. The calibration is based on the power spectrum of the Brownian motion of a dielectric bead trapped in the tweezers. Precision is achieved by accounting for a number of factors that affect this power spectrum. First, cross-talk between channels in 2D position measurements is tested for, and eliminated if detected. Then, the Lorentzian power spectrum that results from the Einstein-Ornstein-Uhlenbeck theory, is fitted to the low-frequency part of the experimental spectrum in order to obtain an initial guess for parameters to be fitted. Finally, a more complete theory is fitted, a theory that optionally accounts for the frequency dependence of the hydrodynamic drag force and hydrodynamic interaction with a nearby cover slip, for effects of finite sampling frequency (aliasing), for effects of anti-aliasing filters in the data acquisition electronics, and for unintended “virtual” filtering caused by the position detection system. Each of these effects can be left out or included as the user prefers, with user-defined parameters. Several tests are applied to the experimental data during calibration to ensure that the data comply with the theory used for their interpretation: Independence of x- and y-coordinates, Hooke's law, exponential distribution of power spectral values, uncorrelated Gaussian scatter of residual values. Results are given with statistical errors and covariance matrix.
Program summary
Title of program: tweezercalibCatalogue identifier: ADTVProgram obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland.Program Summary URL:http://cpc.cs.qub.ac.uk/summaries/ADTVComputer for which the program is designed and others on which it has been tested: General computer running MatLab (MathWorks Inc.).Programming language used: MatLab (MathWorks Inc.). Uses “Optimization Toolbox” and “Statistics Toolbox”.Memory required to execute with typical data: Of order 4 times the size of the data file.High speed storage required: NoneNo. of lines in distributed program, including test data, etc.: 133 183No. of bytes in distributed program, including test data, etc.: 1 043 674Distribution format: tar gzip fileNature of physical problem: Calibrate optical tweezers with precision by fitting theory to experimental power spectrum of position of bead doing Brownian motion in incompressible fluid, possibly near microscope cover slip, while trapped in optical tweezers. Thereby determine spring constant of optical trap and conversion factor for arbitrary-units-to-nanometers for detection system.Method of solution: Elimination of cross-talk between quadrant photo-diode's output channels for positions (optional). Check that distribution of recorded positions agrees with Boltzmann distribution of bead in harmonic trap. Data compression and noise reduction by blocking method applied to power spectrum. Full accounting for hydrodynamic effects: Frequency-dependent drag force and interaction with nearby cover slip (optional). Full accounting for electronic filters (optional), for “virtual filtering” caused by detection system (optional). Full accounting for aliasing caused by finite sampling rate (optional). Standard non-linear least-squares fitting. Statistical support for fit is given, with several plots suitable for inspection of consistency and quality of data and fit.Restrictions on the complexity of the problem: Data should be positions of bead doing Brownian motion while held by optical tweezers. For high precision in final results, data should be time series measured over a long time, with sufficiently high experimental sampling rate: The sampling rate should be well above the characteristic frequency of the trap, the so-called corner frequency. Thus, the sampling frequency should typically be larger than 10 kHz. The Fast Fourier Transform applied requires the time series to contain 2n data points, and long measurement time is obtained with n>12-15. Finally, the optics should be set to ensure a harmonic trapping potential in the range of positions visited by the bead. The fitting procedure checks for harmonic potential.Typical running time: (Tens of) minutesUnusual features of the program: NoneReferences: The theoretical underpinnings for the procedure are found in [K. Berg-Sørensen, H. Flyvbjerg, Rev. Sci. Instrum. 75 (3) (2004) 594]. 相似文献88.
Isotopic variations of Zn in biological materials 总被引:3,自引:0,他引:3
Stenberg A Andrén H Malinovsky D Engström E Rodushkin I Baxter DC 《Analytical chemistry》2004,76(14):3971-3978
Variations in the isotopic composition of Zn present in various biological materials were determined using high-resolution multicollector inductively coupled plasma mass spectrometry (MC-ICPMS), following digestion and purification by anion exchange chromatography. To correct for differences in instrumental mass discrimination effects between samples and standards, Cu was employed as an elemental spike. Complementary analyses of Zn separates by sector field ICPMS instruments revealed that the concentrations of the majority of potentially interfering elements were reduced to negligible levels. Residual spectral interferences resulting from (35)Cl(16)O(2)(+), (40)Ar(14)N(2)(+), and (40)Ar(14)N(16)O(+) could be instrumentally resolved from the (67)Zn, (68)Zn, and (70)Zn ion beams, respectively, during measurement by MC-ICPMS. The only other observed interference in the Cu and Zn mass range that could not be effectively eliminated by high-resolution multicollection resulted from (35)Cl(2)(+), necessitating modification of the sample preparation procedure to allow accurate (70)Zn detection. Complete duplication of the entire analytical procedure for human whole blood and hair, as well as bovine liver and muscle, provided an external reproducibility of 0.05-0.12 per thousand (2sigma) for measured delta(66/64)Zn, delta(67/64)Zn, and delta(68/64)Zn values, demonstrating the utility of the method for the precise isotopic analysis of Zn in biological materials. Relative to the selected Zn isotopic standard, delta(66/64)Zn values for biological samples varied from -0.60 per thousand in human hair to +0.56 per thousand in human whole blood, identifying the former material as the isotopically lightest Zn source found in nature to date. 相似文献
89.
Gulliksen A Solli L Karlsen F Rogne H Hovig E Nordstrøm T Sirevåg R 《Analytical chemistry》2004,76(1):9-14
Real-time nucleic acid sequence-based amplification (NASBA) is an isothermal method specifically designed for amplification of RNA. Fluorescent molecular beacon probes enable real-time monitoring of the amplification process. Successful identification, utilizing the real-time NASBA technology, was performed on a microchip with oligonucleotides at a concentration of 1.0 and 0.1 microM, in 10- and 50-nL reaction chambers, respectively. The microchip was developed in a silicon-glass structure. An instrument providing thermal control and an optical detection system was built for amplification readout. Experimental results demonstrate distinct amplification processes. Miniaturized real-time NASBA in microchips makes high-throughput diagnostics of bacteria, viruses, and cancer markers possible, at reduced cost and without contamination. 相似文献
90.
Isotope ratios and elemental concentrations were measured in aqueous solutions sampled at varying distances from sources of Fe or Zn ions. The measurements reveal fractionation of isotopes resulting from pure diffusion in solution. Our data demonstrate that diffusion alone can cause changes in (56)Fe/(54)Fe and (66)Zn/(64)Zn isotope ratios in excess of -0.3 per thousand. These findings thus confirm previous suspicions that transport processes contribute to observed variations in isotopic compositions. Diffusion must therefore be considered when attempting to make inferences from isotope measurements on samples originating from aqueous systems where concentration gradients may develop. 相似文献