Antifungal activity of isothiocyanates extracted from horseradish (Armoracia rusticana) root against pathogenic dermal fungi

Food Science and Biotechnology - To develop natural antifungal agents against pathogenic dermal fungi, the antifungal activity of isothiocyanates (ITCs) extracted from horseradish (Armoracia...     

Angle estimation error reduction method using weighted IMM and least squares

International Journal of Control, Automation and Systems - This paper proposes a new approach to reduce target estimation error, especially the measurement angle, when applied to medium- and...     

Spongiform immobilization architecture of ionotropy polymer hydrogel coentrapping alcohol oxidase and horseradish peroxidase with octadecylsilica for optical biosensing alcohol in organic solvent

An organic-phase optical alcohol biosensor consisting of alcohol oxidase and horseradish peroxidase coimmobilized in a spongiform hydrogel matrix of hydroxethyl carboxymethyl cellulose, an adduct of 3-methoxy-4-ethoxy benzaldehyde, 4-tert-butylpyridinium acetohydrazone, silica gel particles, and octadecylsilica particles in conjunction with an optical oxygen transducer has been successfully fabricated. The novel enzyme entrapment structure was mainly characterized with desirable solvent permeability, high efficiency of mass transfer for reactants, and good accessibility and stability of the immobilized enzymes. The biosensor could work in water-miscible solvent such as a solvent mixture of acetonitrile and phosphate aqueous buffer, as well as hydrophobic organic solvent such as n-hexane. The biosensor had the highest sensitivity to methanol in both solvent systems. Under the stop-flow mode, the biosensor had the analytical working ranges from 80 microM to 90 mM methanol in n-hexane and 0.10 to 90 mM methanol in acetonitrile/buffer. When the biosensor functioned in n-hexane, it could take benzaldehyde as an alcohol substrate and was free from any pH disturbance. In the presence of coimmobilized horseradish peroxidase, the operational life of the biosensor was 60 assays and the shelf life was longer than two weeks. The biosensor has been satisfactorily applied to the determination of methanol in commercial gasoline-methanol blend samples.     

Design of magnetically suspended frictionless manipulator

Magnetically suspended frictionless manipulator is designed to improve the resolution and position accuracy. In order to increase the dynamic stability, the magnetically suspended manipulator is constructed using push-and-push forces. Using the force analysis, the design and modeling processes of the manipulator are achieved. The proposed modeling process is experimentally verified from free vibration of the manipulator. Comparison is made between the natural frequencies from the modeled dynamic equation and those from experimentally obtained.     

Effects of Geometrical Uncertainties on Electrocardiography

This paper investigates the influence of uncertainties in geometrical coordinates on calculated torso and epicardial potentials. Two types of sources, spherical epicardial and multipolar, are both considered. A concentric sphere model with the epicardial surface represented by a unit sphere and the torso surface represented by a spherical surface of radius 1.4 is utilized. While the representation of biological surfaces with spheres is a highly idealized situation, the dimensions chosen and the approximations utilized are such that the results should be indicative of those using measured biological coordinates.     

Oxidation behavior of IG and NBG nuclear graphites

This work studies the oxidation-induced characteristics of four nuclear graphites (NBG-17, NBG-25, IG-110, and IG-430). The oxidation characteristics of the nuclear graphites were measured at 600 °C. The surface properties of the oxidation graphites were characterized by means of scanning electron microscopy, X-ray photoelectron spectroscopy, and contact angle methods. The N₂/77 K adsorption isotherm characteristics, including the specific surface area and micropore volume, were investigated by means of BET and t-plot methods. The experimental results show an increase in the average pore size of graphites; they also show that oxidation produces the surface functional groups on the graphite surfaces. The surface area of each graphite behaves in a unique manner. For example the surface area of NBG-17 increases slightly whereas the surface area of IG-110 increases significantly. This result confirms that the original surface state of each graphite is unique.     

A separate effect test on the cooling behavior in a pressurized water reactor core under a low reflooding rate condition by using ATLAS and RELAP5/MOD3.3 code assessment

A separate effect test was performed on the cooling behavior in a PWR core under a low reflooding rate condition by using the ATLAS (Advanced Thermal–Hydraulic Test Loop for Accident Simulation) which is a thermal–hydraulic integral effect test facility for the pressurized water reactors APR1400 and OPR1000. Although several integral tests for the reflood phase of a large break loss of coolant accident (LBLOCA) of APR1400 have been performed with the ATLAS, the previous integral effect tests for the reflood phase of a LBLOCA are not easily simulated by existing codes, such as the RELAP5/MOD3, due to a unique phenomena in ATLAS, that resulted from an injection of large amount of subcooled water onto the heated wall of which temperature was higher than the target value.     

Experimental study on the blowdown load during the steam generator feedwater line break accident in the evolutionary pressurized water reactor

Integral effect tests using the ATLAS facility were performed to obtain the thermal-hydraulic parameters such as dynamic and static pressures, local temperatures, and flow rates during a feedwater line break of a steam generator. The break of a feedwater line was simulated using a double rupture disc assembly in order to satisfy the requirements for the break opening time of around a few milliseconds. In the present study, estimated break opening time was less than 1.5 ms and broken areas were 48.1% and 93.4% of the feedwater line, respectively. The maximum dynamic pressures of about 1.57 bar were obtained inside of feedwater box that was closest to the break location of the feedwater line. After the break of the feedwater line, propagation of the pressure wave along the distance from the break location inside the steam generator was clearly and pertinently observed in all the tests. From a structural integrity point of view, however, the risk induced by this maximum dynamic load could be treated to be insignificant.     

Socket weld integrity in nuclear piping under fatigue loading condition

The purpose of this paper is to evaluate the integrity of socket weld in nuclear piping under the fatigue loading. The integrity of socket weld is regarded as a safety concern in nuclear power plants because many failures have been world-widely reported in the socket weld. Recently, socket weld failures in the chemical and volume control system (CVCS) and the primary sampling system (PSS) were reported in Korean nuclear power plants. The root causes of the socket weld failures were known as the fatigue due to the pressure and/or temperature loading transients and the vibration during the plant operation. The ASME boiler and pressure vessel (B & PV) Code Sec. III requires 1/16 in. gap between the pipe and fitting in the socket weld with the weld leg size of 1.09 × t₁, where t₁ is the pipe wall thickness. Many failure cases, however, showed that the gap requirement was not satisfied. In addition, industry has demanded the reduction of weld leg size from 1.09 × t₁ to 0.75 × t₁. In this paper, the socket weld integrity under the fatigue loading was evaluated using three-dimensional finite element analysis considering the requirements in the ASME Code. Three types of loading conditions such as the deflection due to vibration, the pressure transient ranging from P = 0 to 15.51 MPa, and the thermal transient ranging from T = 25 to 288 °C were considered. The results are as follows; (1) the socket weld is susceptible to the vibration where the vibration levels exceed the requirement in the ASME operation and maintenance (OM) code. (2) The effect of pressure or temperature transient load on socket weld in CVCS and PSS is not significant owing to the low frequency of transient during plant operation. (3) ‘No gap’ is very risky to the socket weld integrity for the systems having the vibration condition to exceed the requirement specified in the ASME OM Code and/or the transient loading condition from P = 0 and T = 25 °C to P = 15.51 MPa and T = 288 °C. (4) The reduction of the weld leg size from 1.09 × t₁ to 0.75 × t₁ may induce detrimental effect on the socket weld integrity.     

Efficacy assessment of independent severe accident mitigation measures in OPR1000 using MELCOR code

In-vessel and ex-vessel mitigation strategies have been revisited to improve the severe accident management (SAM) for operating nuclear power plants. Because independent mitigation measures tend to produce positive and adverse effects simultaneously, it is necessary to investigate the efficacy of individual measures by means of proper quantification. Thus, in the present study we investigated the overall efficacy of existing SA mitigation strategies prepared for the Optimized Power Reactor 1000 MWe (OPR1000) by means of MELCOR 1.8.6 code. The numerical evaluation showed that the Mitigation-01, feeding water into the steam generators, is the most effective among the other mitigations. In addition, Mitigation-02, reactor coolant system depressurization, could not mitigate the SA sufficiently when applied individually. Among the four ex-vessel mitigation strategies, execution of containment spray was effective in removing most of the aerosol fission product but also intensified hydrogen combustion by increasing the partial hydrogen pressure owing to steam condensation. Mitigation-07, operation of passive autocatalytic recombiners (PARs), could reduce the hydrogen concentration, though the catalytic reaction was predicted to increase the containment pressure. In conclusion, this study suggests that mitigation measures should be carefully selected, and that counteracting measures should be prepared to minimize potential adverse effects.