Effect of thrombolytic therapy on pulmonary-capillary blood volume in patients with pulmonary embolism

To compare the effects of heparin thrombolytic agents in pulmonary thromboembolic disease, we randomly assigned 40 patients with pulmonary emboli but without other clinical cardiopulmonary disease either to heparin followed by oral anticoagulants (21 patients) or to urokinse or streptokinase followed by heparin and then by oral anticoagulants (19 patients). The effects on pulmonary-capillary blood volume and diffusing capacity were compared at two weeks and at one year. The pulmonary-capillary blood volume (in milliliters per square meter of body-surface area) was abnormally low (30 +/- 2.4) [+/- S.E.]; normal, 47 +/- 1.5) in the heparin-treated group at two weeks and remained unchanged at one year. In contrast, it was normal (45 +/- 2.5) in the group receiving thrombolytic agents, both at two weeks and at one year (P < 0.001). The pulmonary diffusing capacity was reduced to 69% of the predicted value in the heparin group at two weeks and 72% at one year, whereas it was 85% of the predicted value in the thrombolytic group at two weeks and 93% at one year (P < 0.001). These results indicate that thrombolytic agents allow more complete resolution of thromboemboli than do heparin and anticoagulants and that they improve capillary perfusion and diffusion.     

Bennett house: Aboriginal heritage as real estate in East Perth

Abstract

As the mansions materialised in refurbished East Perth on the Swan River, a battle between the East Perth Redevelopment Authority and Perth's indigenous community over a land swap culminated in demolition of a heritage building significant to the Stolen Generations. This case study unravels the complex relations and practices underpinning Bennett House's demolition, resonant of other planning decisions involving Aboriginal sites in Western Australia.     

Development of enzyme biosensor based on trypsin and conductometric thin-film electrodes for protein and artificial substrates determination

ULTRA was established on the 1st April 1990, to consider applications made by registered medical practitioners seeking approval to transplant an organ between 2 living unrelated persons in the United Kingdom.     

The creation of a legal-standards basis for the economic validation of nature-preserving activities in health resorts

In patients with pulmonary tuberculosis, intestinal dysbacteriosis has clinical and bacteriological features characterized by the short-age of bifidobacteria (in 88-92%), by changes in the composition of Escherichia coli strains (in 38-42%), by the presence of Candida (in 58-62%), Proteus in half the patients, and by associated dysbacteriosis. Most (75%) patients show Stage III-IV intestinal dysbiosis formed after 3-4 months of continuous chemotherapy. There is a direct relationship between the magnitude of dysbiotic disorders and the duration of chemotherapy.