Evaluation of scenario-based modularization for lifecycle design

Although modular design is a key technique for lifecycle design, effectiveness of modularity on environmental consciousness is not clear. This paper proposes an evaluation method of modular product from the viewpoint of resource efficiency. First, a product is modularized by applying our modularization method based on its lifecycle scenario. Second, the modular structure is evaluated by assuming that each module goes through preferable lifecycle paths (e.g., upgrading, reuse, and closed-loop recycling) designated by the scenario but unmodularized components go through unpreferable paths. This paper also illustrates a case study in order to discuss effectiveness of the proposed method.     

Hydrogen permeation under high pressure conditions and the destruction of exposed polyethylene-property of polymeric materials for high-pressure hydrogen devices (2)-

Aiming to elucidate physical property affecting to hydrogen gas permeability of polymer materials used for liner materials of storage tanks or hoses and sealants under high-pressure environment, as model materials with different free volume fraction, five types of polyethylene were evaluated using two methods. A convenient non-steady state measurement of thermal desorption analysis (TDA), and steady-state high-pressure hydrogen gas permeation test (HPHP) were used both under up to 90 MPa of practical pressure. The limit of TDA method of evaluation for the specimens suffering fracture during decompression process after hydrogen exposure was found. Permeability coefficient decreased with the decrease of diffusion coefficient under higher pressure condition. Specific volume and degree of crystallinity under hydrostatic environment were measured. The results showed that the shrinkage in free volume caused by hydrostatic effects of the applied hydrogen gas pressure decreases diffusion coefficient, resulting in the decrease of permeability coefficient with the pressure rise.     

The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine

The Caenorhabditis elegans elt-2 gene encodes a single-finger GATA factor, previously cloned by virtue of its binding to a tandem pair of GATA sites that control the gut-specific ges-1 esterase gene. In the present paper, we show that elt-2 expression is completely gut specific, beginning when the embryonic gut has only two cells (one cell cycle prior to ges-1 expression) and continuing in every cell of the gut throughout the life of the worm. When elt-2 is expressed ectopically using a transgenic heat-shock construct, the endogenous ges-1 gene is now expressed in most if not all cells of the embryo; several other gut markers (including a transgenic elt-2-promoter::lacZ reporter construct designed to test for elt-2 autoregulation) are also expressed ectopically in the same experiment. These effects are specific in that two other C. elegans GATA factors (elt-1 and elt-3) do not cause ectopic gut gene expression. An imprecise transposon excision was identified that removes the entire elt-2 coding region. Homozygous elt-2 null mutants die at the L1 larval stage with an apparent malformation or degeneration of gut cells. Although the loss of elt-2 function has major consequences for later gut morphogenesis and function, mutant embryos still express ges-1. We suggest that elt-2 is part of a redundant network of genes that controls embryonic gut development; other factors may be able to compensate for elt-2 loss in the earlier stages of gut development but not in later stages. We discuss whether elements of this regulatory network may be conserved in all metazoa.     

Frequent gains on chromosome arms 1q and/or 8q in human endometrial cancer

Comparative genomic hybridization (CGH) was employed to survey genomic regions with increased and decreased copy number of the DNA sequence in 15 endometrial cancers [10 cases with microsatellite instability positive (MI+) and 5 cases with MI-]. Twelve of these 15 tumors (80%) showed abnormalities in copy number at one or more of the chromosomal regions. There were no regions with frequent chromosomal losses. Conversely, 11 of 15 cases (73%) showed gains on chromosome arms 1q (8/15; 53%) and/or 8q (6/15; 40%). Concordant gains of both chromosome arms 1q and 8q were observed in all three endometrial cancers of histological grade 3. These results suggest that these two chromosomal regions may contain genes whose increased expression contributes to development and/or progression of endometrial carcinogenesis. Two cases were further analyzed by fluorescence in situ hybridization (FISH) using three probes on chromosome 1 and two probes on chromosome 8 to more accurately determine increases in copy number. We found gains of chromosome 1q to 2.9-3.6 copies per cell and on 8q to 4.4 copies per cell.     

A MEMS conical spring actuator array

A new MEMS conical spring actuator array is proposed. Previously, we have developed conical spring microactuators having a long stroke (180 /spl mu/m) in the out-of-plane direction. However, the maximum output force and the packing density were not satisfactory. In the present paper, mechanical and electrical models of a conical spring are described for the calculation of the maximum output force and the driving voltage. Geometrical parameters were optimized using these models and a new geometry for the actuator was derived. The new geometry incorporates a wider and thicker spring that increased the maximum output force from 0.087 mN up to 0.83 mN. The packing density was increased up to 1 actuator/mm/sup 2/ using an additional interconnect layer. In addition, the driving voltage was decreased using a thinner insulating layer. The use of an ac drive prevented the sticking of the actuator during operation. A detailed investigation of the ac drive was also performed.     

Surface modification of a glass microchannel for the formation of multiple emulsion droplets

We herein report a method for the preparation of a glass microchannel capable of forming multiple emulsion droplets (i.e., water-in-oil-in-water and oil-in-water-in-oil) by locally controlling the wettability of the glass microchannel. Production of multiple emulsion droplets using a glass microchannel requires partial control of its wettability using a method that consists of two steps: (1) hydrophobization of a whole glass microchannel by filling the microchannel with octadecyltrichlorosilane (OTS) solution, and (2) local hydrophilization of the OTS-treated glass microchannel by exposure to ultraviolet light through a mask. However, conditions for the preparation of OTS-SAMs for controlling microchannel wettability and subsequent multiple emulsion droplet formation have not yet been reported. In this study, we investigated the conditions required to form multiple emulsion droplets and demonstrated formation of multiple emulsion droplets using a treated glass microchannel with multiple junctions. The glass microchannel prepared according to this method was able to form various aqueous and organic droplets due to its resistance to swelling.     

Impact of environment factors on solar cell parameters of a-Si∥μc-Si photovoltaic modules

The behavior of amorphous silicon∥micro crystalline silicon (a-Si∥μc-Si) tandem-type photovoltaic (PV) module is complex because the output current is limited by the lower current component cell. Also, the outdoor behaviors are not fully understood. The impact of environment factors on solar cell parameters of a-Si∥μc-Si PV module was quantitatively analyzed and the module was compared with other silicon-based PV modules (single crystalline silicon (sc-Si) and amorphous silicon (a-Si)). The contour maps of solar cell parameters were constructed as a function of irradiance and module temperature. The contour map of a-Si∥μc-Si PV modules is similar to that of a-Si modules. The results imply that output characteristics of a-Si∥μc-Si PV modules are mainly influenced by the a-Si top cell. Furthermore, the efficiency of a-Si∥μc-Si PV modules was compared other solar cell parameters and the contour map of efficiency is similar to that of fill factor.