Reduction mammaplasty improves symptoms of macromastia

The condition macromastia has not been defined and characterized precisely by the medical community. Whether the patient with hypertrophic breasts is a candidate for or can be helped by reduction mammaplasty is unclear to both the medical and the lay community. A prospective study of 39 women undergoing reduction mammaplasty surgery was initiated to answer these questions. Patients rated the severity of their somatic pain symptoms and discomfort before reduction mammaplasty and again after complete recovery. The severity of their symptoms and complaints was numerically graded and analyzed. These data were compared with similar data obtained from 40 "small-breasted" women of similar age. Headache, neck pain, back pain, shoulder pain, and bra strap groove pain were present in 60 to 92 percent of patients, and 97 percent of patients had at least three of these pain symptoms preoperatively. All the patients had reduction of their pain symptomatology postoperative, and 25 percent of the study patients had total elimination of pain symptoms by reduction mammaplasty. The postoperative incidence and severity of pain symptoms and discomfort complaints were statistically equivalent to or less than the levels in the control group.     

Action diversity in a simulation of the Israeli-Palestinian conflict

This article explores the strategies used by Israeli students to resolve the Israeli-Palestinian conflict in the interactive computer game, PeaceMaker. Students played PeaceMaker in the roles of both the Israeli Prime Minister and the Palestinian President in random order. Students must take actions satisfying constituents on both sides of the conflict in order to win the game. The diversity of actions taken in each role was measured. Several hypotheses test the degree to which Israeli students, depending on which role they played and their own demographic variables, exploited a consistent set of actions or explored a more diverse range of actions across three main types: construction, political, and security. The results show that (1) greater action diversity increases success in both roles, (2) Israeli students engaged in less diverse actions when playing the Israeli role than when playing the Palestinian role, (3) students’ religiosity and political Hawkishness negatively predicted action diversity when playing the Palestinian role, and (4) action diversity mediates the relationship between a student’s background knowledge about the conflict and success in the Israeli role. The significance of these findings for understanding attitudes about the Israeli-Palestinian conflict are discussed, including implications for conflict resolution more generally.     

Bringing Scheme programming to the iPhone—Experience

The iPhone SDK provides a powerful platform for the development of applications that make use of iPhone capabilities, such as sensors, GPS, Wi‐Fi, or Bluetooth connectivity. We observe that so far the development of iPhone applications has mostly been restricted to using Objective‐C. However, developing applications in plain Objective‐C on the iPhone OS suffers from limitations, such as the need for explicit memory management and lack of syntactic extension mechanism. Moreover, when developing distributed applications in Objective‐C, programmers have to manually deal with distribution concerns, such as service discovery, remote communication, and failure handling. In this paper, we discuss our experience in porting the Scheme programming language to the iPhone OS and how it can be used together with Objective‐C to develop iPhone applications. To support the interaction between Scheme programs and the underlying iPhone APIs, we have implemented a language symbiosis layer that enables programmers to access the iPhone SDK libraries from Scheme. In addition, we have designed high‐level distribution constructs to ease the development of distributed iPhone applications in an event‐driven style. We validate and discuss these constructs with a series of examples, including an iPod controller, a maps application, and a distributed multiplayer Scrabble‐like game. We discuss the lessons learned from this experience for other programming language ports to mobile platforms. Copyright © 2011 John Wiley & Sons, Ltd.     

Oxidation State of Titanium in CaO‐SiO2‐TiOx Slags at 1873K

Oxidation state of titanium was determined in CaO‐SiO₂‐TiO_x slags in the composition range 25‐53 percent CaO, 27‐46 percent SiO₂, 10‐55 percent TiO_x at 1873K using gas equilibration method. In the experiments, slags with different titanium oxide contents were equilibrated with a known carbon monoxide and carbon dioxide ratio. The results were used to determine the Ti³⁺ and Ti⁴⁺ contents as well as the activity coefficient ratio of corresponding oxides in the slag. The dependence of the activity coefficient ratio as a function of oxygen partial pressure was determined.     

An efficient algorithm for gossiping in the multicasting communication environment

We present an algorithm for the gossiping problem defined over an n processor communication network, N, where message multicasting is allowed. The algorithm generates a communication schedule with a total communication time at most N+r, where r is the radius of the network. Our algorithm begins by constructing a spanning tree (or tree network T) with the least possible radius. Then, all the communications are carried out in the tree network as follows: each processor waits its turn to transmit "almost" consecutively to its parent and children all the messages in its subtree. During other times, each processor transmits to its children all the messages emanating elsewhere in the network.     

Successful Management of Valproate Overdose by a Combination of Extracorporeal Therapies

Valproic acid toxicity is not infrequent and is difficult to treat, as there is no specific antidote. In the past, this drug was considered unremovable by extracorporeal methods because of the highly protein bound state (90–95%). However, recent reports suggest that the toxicokinetics of valproate vary considerably from the pharmacokinetics at therapeutic levels, and at higher concentrations protein‐binding sites become saturated. The drug's relatively low molecular weight (144 Da), small volume of distribution (0.13–0.23 L/kg), and saturable protein binding render it potentially amenable to extracorporeal removal, but published experience is scant and there are only a few reported instances in which patients were successfully treated with extracorporeal methods. Here we report the case of a patient with serious valproate toxicity treated with simultaneous “in series” hemodialysis and hemoperfusion followed by continuous veno‐venous hemodiafiltration. A 35‐year‐old homeless male presented to the emergency department after ingesting 120 pills of valproic acid. Initial valproic acid level was 59 µg/mL. Urine drug screen was negative and serum chemistries including LFTs were normal. He was treated with activated charcoal and admitted to the intensive care unit. 4 h later, he developed respiratory failure and became hemodynamically unstable. He was intubated and successfully resuscitated. Subsequently, the valproic acid level was found to be 553 µg/mL and a decision was made to employ extracorporeal methods for drug removal. “In series” hemodialysis and hemoperfusion were done for 4 h and simultaneous blood samples for measurement of valproic acid levels were obtained as blood entered the hemoperfusion column (arterial) and as it exited the hemodialysis membrane (venous). Extraction ratio, whole blood, and plasma clearances were calculated and they compared substantially with the published data. The above measures decreased valproate levels from 572.6 (pre‐dialysis level) to 203.2 µg/mL. This was followed by continuous veno‐venous hemodiafiltration for 18 h, which sustained the drug removal and prevented significant post‐dialytic rebound. This is the first reported instance in which these three methods were administered together successfully in the management of valproic acid toxicity.     

An iterative thresholding algorithm for image segmentation

A thresholding technique is developed for segmenting digital images with bimodal reflectance distributions under nonuniform illumination. The algorithm works in a raster format, thus making it an attractive segmentation tool in situations requiring fast data throughput. The theoretical base of the algorithm is a recursive Taylor expansion of a continuously varying threshold tracking function.     

Impact of the Ge Content on the Bandgap-Narrowing Induced Leakage Current of Recessed $hbox{Si}_{1 - x}hbox{Ge}_{x}$ Source/Drain Junctions

The purpose of this paper is to evaluate the impact of process-induced stress on the generation current of fully strained Si_1- xGex source/drain junctions. The Ge content of the compressively strained SiGe epitaxial layer plays a key role in the tensile stress levels present in the underlying Si substrate. Current-voltage (I-V) measurements were employed to further investigate the leakage current enhancement due to the stress-induced bandgap narrowing in the Si depletion region, when no extended defects are formed. An empirical approach is proposed to describe the Ge content dependence of the bandgap-shrinkage-induced leakage current. An increase of the intrinsic carrier concentration as a function of the stress mismatch is observed. Moreover, the role of the epilayer thickness in the generation current is also discussed.     

Indirect Determination of Water in Nitroglycerin-Nitrocellulose Pastes by gas-liquid chromatography

A gas-liquid chromatographic procedure was developed in connection with the determination of water in nitroglycerin-nitrocellulose pastes. The method is based on the reaction of water with 2,2-dimethoxypropane and its conversion to acetone which is subsequently determined. The technique is simple, rapid, and shows good accuracy and precision. A simplified method, which is less accurate but does not involve chromatography, is also proposed.