Estimation and hypothesis testing of treatment effects in animal reproductive toxicology studies

Healy (1) and Dempster et al. (8) proposed statistical methods to evaluate the treatment effects in animal reproductive toxicology research. Both methods assume homogeneous variance for the dams and the pups, respectively, in all the treatment groups. In this paper, via mixed effect modeling, we propose a method to estimate the treatment effects allowing heterogeneous variances for the dams and the pups, respectively, in different treatment groups. Covariates will also be included in the model. A procedure to test the fixed effects is also discussed. An example from an animal reproductive toxicological study is used to illustrate the procedures.     

Histomorphometric study in children with idiopathic nephrotic syndrome

There is agreement on the clinical diagnostic criteria for acute inflammatory demyelinating polyneuropathy (AIDP/GBS) however, there is lack of consensus for detection of demyelination. In order to critically evaluate the prevailing criteria, sixty-six patients who fulfilled NINCDS criteria and had typical features of GBS were studied for electrophysiological abnormalities of peripheral nerves by using standard methods (median, common peroneal, sural and ulnar) between 1 to 12 weeks after the onset of symptoms. The commonest abnormality on motor nerve conduction study was prolonged distal latency (75%-83%) followed by reduction in CMAP amplitude (63%-82%), decreased velocity (48%-62%), conduction block (17%-39%) and f-wave abnormalities (37.8%-59%). Sensory conduction abnormalities were detected in over 20% of median, 25% of ulnar and 33% of sural nerves. All the patients had abnormality of at least two motor conduction parameters in one nerve when values beyond 2 SD of the mean were considered abnormal and over 70% of patients had three abnormalities in two nerves or two abnormalities in three nerves. Comparison with the prevailing criteria for demyelination revealed that the number of patients fulfilling them varied widely: Albers et al. (1985): 74.2%, Albers et al. (1989): 40.9% and Cornblath: 30.3%. We believe that the current criteria for detection of demyelination in acute neuropathy are too strict, underestimate the underlying pathology in GBS and need reassessment.     

单液晶光阀彩色大屏幕投影显示

设计一电路,将彩色图象信息编码到黑白CRT的亮度之中,并将其写入液晶光阀,用白光读出,当编码合适时,读出的象颜色可与原图像一致。本文讨论了这一技术原理并进行了单液晶光阀彩色大屏幕投影的实验验证。     

An isolated ZVS/ZCS flyback converter using the leakage inductanceof the coupled inductor

This paper describes a simple and effective way to modify an existing hard-switched flyback power converter into a circuit with zero-voltage switching (ZVS) and zero-current switching (ZCS). The key improvement is to turn the unattractive features of the coupled inductor leakage inductance and snubber capacitor into attractive ones. The coupled inductor leakage inductance and snubber are used to form a quasi-resonant circuit to facilitate ZVS/ZCS of all power devices. The operating principles of the power converter and experimental results are presented     

Analysis of color symbology from the perspective of cultural semiotics focused on Korean costume colors according to the cultural changes

The purpose of this study was to analyze the symbolization of colors as cultural codes, based on costume colors. In order to study the significance of colors in cultural changes, we carried out a quantitative analysis and interpreted it from the perspective of cultural semiotics. The range of this study was focused on Korean costume colors, over diverse diachronic stages of Korean culture. For this study 1535 color samples were collected, measured with a spectrophotometer, and analyzed quantitatively according their diachronic stages of origin. As a result, red, blue, and yellow were found to be the most frequently used colors during the Chosun Dynasty, a period based on Confucianism. These colors acted as cultural codes with cultural significance. During the Modern times pink, light blue, and black increased in frequency and represented the reception of western culture, the changing sex role of women in society, and utilitarianism. In these days, neutral colors and grayish tones of all colors are the most significant colors of high frequency. The use of such colors is closely related to industrialization, mechanization, functionalism, and the changes of women's sex roles in the societies. They are used as cultural codes, especially to emphasize a rational and masculine image rather than a feminine image. © 2006 Wiley Periodicals, Inc. Col Res Appl, 32, 71–79, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/col.20290     

Preceramic organoboron–silicon polymers

Several boron-containing organosilicon polymers were synthesized from a sodium-coupling reaction of silicon and boron halides with and without alkyl halide in hydrocarbon solvents. The B–Si preceramic polymers were characterized using techniques such as IR, UV, and NMR spectrometry, gel permeation chromatography, elemental analysis, molecular weight measurement, and thermal analyses (TGA, DSC, DTA, and TMA). The chemical structures of the preceramic polymers were postulated based on the analytical results. Black ceramic materials were obtained from the precursor polymers upon thermal degradation at temperatures above 1000°C in an inert atmosphere. The precursor polymers had a ceramic yield of up to 70%. Thermogravimetric analysis of the ceramic material in air at a flow rate of 100 mL/min showed it was stable up to 1000°C with little weight gain or loss. Several methods were used to characterize the ceramic materials: XRD, solid NMR, high-temperature DTA, elemental analysis, and acid digestion. The analyses indicated that the ceramic materials comprised a mixture of silicon carbide (SiC), silicon borides (SiB₄, SiB₆), and amorphous Si–B–C ceramics, with small amounts of silica and free silicon.     

Modeling the Absorption of Acidic Gases by Alkanolamine Solutions Incorporating Several Reactions

A general model, based on double film theory, is developed to study absorption with chemical reactions. In the liquid film region, the model is a set of differential equations that describe the mass transfer accompanying several chemical reactions; the resolution of the system is achieved by the finite difference method using an implicit scheme combined with Newton's method. Continuity equations and equilibrium coefficients are exploited in the treatment of the bulk region, which is based on the Newton‐Raphson method; the results are used directly as boundary conditions in the liquid film equations. Maxwell‐Stefan equations have been used as a rigorous approach in this model.     

Pore‐free mold‐pattern‐transfer method for barrier ribs of HD PDPs

Abstract— Among various barrier‐rib manufacturing processes, the mold‐pattern‐transfer method has potential to reduce processing cost as well as the manufacture of high‐resolution pixels. In this study, the effects of major processing variables of the mold‐pattern‐transfer process on the formation of air‐trapped pores within barrier ribs were examined. The results indicated that with an optimum combination of the processing variables, barrier ribs without trapped defects can be produced, demonstrating the possibility of reducing the number of processing steps and costs of barrier ribs.