High purity pion beam at TRIUMF

An extension of the TRIUMF M13 low-energy pion channel designed to suppress positrons based on an energy-loss technique is described. A source of beam channel momentum calibration from the decay π⁺→e⁺ν is also described.     

Design optimisation of a solar-energy harnessing system for stimulating an irrigation pump

Water from below ground level is to be raised, for the irrigation of a desert area near Cairo, Egypt, by harnessing solar power. The solar-energy collector is an array of gravity-return heat pipes, each surrounded by a cylindrical high-vacuum enclosure. The prime mover, in the form of a multi-vane expander, operates in an organic Rankine-cycle using trichlorotrifluoroethane as the working fluid. For specified conditions, the performances and optimal output temperatures of the collector (so that maximum overall efficiency of the system can be achieved) are predicted.     

Studies of heterocyclic polymers. V. poly (1, 3′-benzobis (iminopyrrolenones))

The synthesis of dimethyl-2, 5-dicyanoterephthalate from 2,5-dibromo-p-xylene and its conversion to 1,3′-benzobis (iminopyrrolenone) are reported. 1,3 -Benzobis (N-phenyliminopyrrolenone) was prepared by reaction of 1,3′-benzobis (iminopyrrolenone) with aniline. The product was a bright yellow crystalline solid which was also formed when dimethyl-2,5-dicyanoterephthalate was condensed with aniline under suitable conditions. Poly (1,3′-benzobis (iminopyrrolenones)) were synthesised by the condensation of 1,3′ -benzobis (iminopyrrolenone) with aromatic diamines and with 1,6-diaminohexane at high temperatures in dimethyl sulphoxide. The degrees of polymerisation of the polymers obtained were low, as judged by the completeness of the condensation reaction. Thermogravimetric analyses of these polymers in air showed that they have 10% weight-loss temperatures in the range 420 to 520°C, for the polymers prepared from aromatic diamines, and of 350°C for the polymer derived from 1,6-diaminohexane. The insoluble, intractable nature of these polymers precluded a thorough study of their structure.     

Composite Nanoarchitectonics with Polythiophene,MWCNTs-G,CuO and Chitosan as a Voltammetric Sensor for Detection of Cd(II) Ions

Journal of Inorganic and Organometallic Polymers and Materials - In this study, we describe an electrochemical method for detecting Cd(II) ions, utilizing a glassy carbon electrode (GCE) modified...     

Toxicity and Metabolism of Layered Double Hydroxide Intercalated with Levodopa in a Parkinson’s Disease Model

Layered hydroxide nanoparticles are generally biocompatible, and less toxic than most inorganic nanoparticles, making them an acceptable alternative drug delivery system. Due to growing concern over animal welfare and the expense of in vivo experiments both the public and the government are interested to find alternatives to animal testing. The toxicity potential of zinc aluminum layered hydroxide (ZAL) nanocomposite containing anti-Parkinsonian agent may be determined using a PC 12 cell model. ZAL nanocomposite demonstrated a decreased cytotoxic effect when compared to levodopa on PC12 cells with more than 80% cell viability at 100 μg/mL compared to less than 20% cell viability in a direct levodopa exposure. Neither levodopa-loaded nanocomposite nor the un-intercalated nanocomposite disturbed the cytoskeletal structure of the neurogenic cells at their IC₅₀ concentration. Levodopa metabolite (HVA) released from the nanocomposite demonstrated the slow sustained and controlled release character of layered hydroxide nanoparticles unlike the burst uptake and release system shown with pure levodopa treatment.     

Development of Drug Delivery Systems Based on Layered Hydroxides for Nanomedicine

Layered hydroxides (LHs) have recently fascinated researchers due to their wide application in various fields. These inorganic nanoparticles, with excellent features as nanocarriers in drug delivery systems, have the potential to play an important role in healthcare. Owing to their outstanding ion-exchange capacity, many organic pharmaceutical drugs have been intercalated into the interlayer galleries of LHs and, consequently, novel nanodrugs or smart drugs may revolutionize in the treatment of diseases. Layered hydroxides, as green nanoreservoirs with sustained drug release and cell targeting properties hold great promise of improving health and prolonging life.     

Adsorption of uranium from sulfate leach liquor using rice straw impregnated with chlorophenyl hydrazinyl pyrazoloquinazolinon

The impregnation of rice straw with 2-amino-3-(2-(4-chlorophenyl)hydrazinyl)-8,8-dimethyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one (CPHPQ) has been used for the recovery of uranium from sulfate leach liquor. The uranium adsorption and elution of solvent impregnated mercerized rice straw (SIMRS) were carried out using a batch technique. The uranium adsorption controlling factors include pH, initial uranium concentration, contact time, S/L ratio, and temperature. Thermodynamic characteristics showed that the adsorption process is exothermic with enthalpy change ΔH = ?152.1 kJ/mol. The kinetics data fit well with a pseudo-second-order model. The equilibrium data fit well with the Langmuir isotherm. Uranium cake was obtained from the eluate solution using hydrogen peroxide as UO₄.2H₂O precipitate.