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91.
Vehicular Ad-hoc Networks (VANETs) will start becoming deployed within the next decade. Among other benefits, it is expected that VANETs will support applications and services targeting the increase of safety on the road, and assist in improving the efficiency of the road transportation network. However, several serious challenges remain to be solved before efficient and secure VANET technology becomes available, one of them been efficient authentication of messages in a VANET. There is a significant body of research work addressing this issue, however, while progress has been made, the challenge is still far from having been resolved and reliable and secure systems ready for deployment becoming available. In this paper, we propose the Privacy Preserving Broadcast Message Authentication (PPBMA) scheme, which, instead of performing asymmetric verification, uses Message Authentication Code (MAC) functionality and HASH operations to authenticate messages. Moreover, we use two-level key hash chain, which assists avoiding message losses. Simulation results demonstrate that PPBMA has superior performances in terms of packet loss rate and message delivery latency when compared to existing solutions. Due to this advantage, it can support emergency and routine messages alike, while existing solutions can only support routine messages.  相似文献   
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PURPOSE: To confirm the efficacy of docetaxel in patients with breast cancer previously treated with one chemotherapy regimen for advanced or metastatic disease and to compare the incidence of fluid retention (FR) and skin toxicity when docetaxel is administered with and without prophylactic corticosteroids. PATIENTS AND METHODS: Eighty-three patients, pretreated with one chemotherapy regimen for metastatic breast cancer (MBC) with bidimensionally measurable and progressive disease, were eligible for this randomized trial. Docetaxel with prophylactic oral antihistamine was administered at a dose of 50 mg/m2 as a 1-hour infusion on days 1 and 8 every 21 days and patients were randomized to receive methylprednisolone (40 mg days -1, 0, 1, 7, 8, and 9 of each cycle) (arm A) or no methylprednisolone (arm B). RESULTS: Twenty-eight patients (34%, 95% confidence interval [CI], 23% to 45%) achieved on objective response. The median time to disease progression and median overall survival time were 5 and 13.5 months, respectively. In total, 415 cycles of docetaxel were administered (arm A: N = 219, median = six; arm B: N = 196, median = five). The most common toxicity observed was grade 3 or 4 neutropenia, which occurred in 79% of patients. Clinically significant nonhematologic side effects included skin reactions and asthenia. In an intent-to-treat analysis, patients who received methylprednisolone premedication had a delayed onset of FR (median time to onset of FR: arm A, 84 days; arm B, 62 days; P = .01) and received a higher median cumulative dose of docetaxel before the onset of FR (arm A, 333 mg/m2; arm B, 215 mg/m2; P = .001). There was no statistically significant difference in the incidence of skin toxicity between the two arms. CONCLUSION: Docetaxel, at this dose and schedule, has definite antitumor activity in pretreated MBC patients. Moreover, this is the first randomized trial to show that corticosteroids have a favorable impact on docetaxel-induced FR.  相似文献   
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Two studies examined contingent take-home medication doses during treatment of opiate or cocaine dependence. In the first study, methadone maintenance patients were randomly assigned to one of two 8-week baseline take-home (TH) conditions differing in frequency of clinic visits per week. This was followed by a 12-week contingency management (CM) procedure in which frequent THs resulted from drug-free urines. Participants receiving more frequent THs during baseline had lower illicit drug use during the first 6 weeks of CM. In the second study, fluoxetine (0-, 20-, 40-mg) TH doses were similarly contingent in treatment of cocaine dependence. The 40-mg group used less cocaine during contingency than did other groups. The combination of fluoxetine and environmental contingencies may produce benefit where neither alone is sufficient. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
96.
The health status of the control plane and the data plane of a GMPLS‐controlled optical network is independent in the physically separated control network implementation. In most control plane designs, besides the topology information, the entities of the routing protocol only record the number of available wavelengths on each link. However, the status of each wavelength is maintained by the entities of the signalling protocol. Without recovery ability of the signalling protocol CR‐LDP, a failure in the control plane will result in the permanent loss of the status information of wavelengths. A mechanism to recover the status information of the wavelengths is proposed. A downstream node maintains a label information database (LID) about assignable (free) labels in each incoming link. A copy of LID is redundantly stored in the upstream node as a label information mirror (LIM). A systematic procedure is proposed to synchronize the contents of a LIM and the corresponding LID. The initialization of a new LDP session with the enhanced recovery mechanism will guarantee the revival of the status information of wavelengths. It can recover multiple control channel failures, but it only applies to single node failure among any pair of adjacent nodes. © Crown copyright 2002. Reproduced with the permission of Her Majesty's Stationery Office. Published by John Wiley & Sons, Ltd.  相似文献   
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An analytical solution for diffusion with homogenous n the order nonlinear chemical reaction in laminar flow of a Newtonian fluid through tubular reactor with unknown boundary conditions is presented. The results of the new solution have been compared with previously published numerical solutions and shown to be accurate.  相似文献   
99.
Controlled release formulation of an herbicide, 2,4-dichlorophenoxyacetate (24D) was developed by the virtue of the formation of organic–inorganic nanohybrid material and its ion exchange property. The inorganic Zn–Al layered double hydroxide (ZAL) was used as a matrix, hosting an active agent or a guest, 24D by self-assembly technique. The resulting material (ZAD) was subsequently used to study the release property of 24D into aqueous solutions containing chloride, carbonate as well as distilled water. The release of the guest 24D was found to be rapid initially followed by a more sustained release thereafter and this behavior was dependent on the type of anions and their concentrations in the release medium, the aqueous solution. The mechanism of release has been interpreted on the basis of the ion exchange process between the 24D anion intercalated into the interlamellae host and carbonate or chloride and/or hydroxyl anions in the aqueous solution.  相似文献   
100.
This paper summarizes comprehensive experimental studies on scaled models of squat bridge columns repaired and retrofitted with advanced composite-material jackets. In the experimental program, a total of 14 half-scale squat circular and rectangular reinforced concrete columns were tested under fully reversed cyclic shear in a double bending configuration. In order to provide a basis for comparison, a total of three as-built columns were tested. Another 10 column samples were tested after being retrofitted with different composite jacket systems. One circular as-built column was repaired after failure. The repair process involved both crack injection as well as addition of carbon/epoxy composite jacket. The repaired column was then retested and evaluated. Experimental results showed that all as-built columns developed an unstable behavior and failed in brittle shear mode. The common failure mode for all retrofitted samples was due to flexure with significant improvement in the column ductility. The repaired column demonstrated ductility enhancement over the as-built sample.  相似文献   
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