一种多晶硅高温压力传感器

制作压力传感器时，在二氧化硅层上淀积多晶硅膜，既可利用优良的机械特性，又可保证压敏电阻与衬底间具有良好的绝缘性，由此可大大提高器件的温度特性。介绍了一种多晶硅压力传感器的原理和设计。实验结果表明，这类传感器具有灵敏度好，精度高等特点，电路工作范围为０－２５０℃，且具有良好的温度稳定性。     

Weight smoothing to improve network generalization

A weight smoothing algorithm is proposed in this paper to improve a neural network's generalization capability. The algorithm can be used when the data patterns to be classified are presented on an n-dimensional grid (n>/=1) and there exists some correlations among neighboring data points within a pattern. For a fully-interconnected feedforward net, no such correlation information is embedded into the architecture. Consequently, the correlations can only be extracted through sufficient amount of network training. With the proposed algorithm, a smoothing constraint is incorporated into the objective function of backpropagation to reflect the neighborhood correlations and to seek those solutions that have smooth connection weights. Experiments were performed on problems of waveform classification, multifont alphanumeric character recognition, and handwritten numeral recognition. The results indicate that (1) networks trained with the algorithm do have smooth connection weights, and (2) they generalize better.     

在经典极限下量子斯特林制冷机的优化

经济利润率是评价一个实际热力装置的主要指标之一。将有限时间热力学，非平衡量子统计理论和yong经济学相结合，导出了量子斯特林制冷机的最大利润率以及对应的性能界限，其结果与实际斯特林制冷机的优化设计和模型评估提供了一个最佳的预选方案。     

Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7

Human papillomavirus (HPV) infection has been causally associated with cervical cancer. We tested the effectiveness of an HLA-A*0201-restricted, HPV-16 E7 lipopeptide vaccine in eliciting cellular immune responses in vivo in women with refractory cervical cancer. In a nonrandomized Phase I clinical trial, 12 women expressing the HLA-A2 allele with refractory cervical or vaginal cancer were vaccinated with four E786-93 lipopeptide inoculations at 3-week intervals. HLA-A2 subtyping was also performed, and HPV typing was assessed on tumor specimens. Induction of epitope-specific CD8+ T-lymphocyte (CTL) responses was analyzed using peripheral blood leukapheresis specimens obtained before and after vaccination. CTL specificity was measured by IFN-gamma release assay using HLA-A*0201 matched target cells. Clinical responses were assessed by physical examination and radiographic images. All HLA-A*0201 patients were able to mount a cellular immune response to a control peptide. E786-93-specific CTLs were elicited in 4 of 10 evaluable HLA-A*0201 subjects before vaccination, 5 of 7 evaluable HLA-A*0201 patients after two vaccinations, and 2 of 3 evaluable HLA-A*0201 cultures after all four inoculations. Two of three evaluable patients' CTLs converted from unreactive to reactive after administration of all four inoculations. There were no clinical responses or treatment toxicities. The ability to generate specific cellular immune responses is retained in patients with advanced cervical cancer. Vaccination with a lipidated HPV peptide epitope appears capable of safely augmenting CTL reactivity. Although enhancements of cellular immune responses are needed to achieve therapeutic utility in advanced cervical cancer, this approach might prove useful in treating preinvasive disease.     

既有钢筋混凝土框架结构抗震加固若干问题探讨

针对钢筋混凝土框架结构抗震加固问题的复杂性 ,本文深入分析了抗震加固结构的受力特征 ,探讨了卸荷对加固构件承载力的影响 ,并针对抗震加固后的“隐含危险转移”问题提出了相应的对策。最后 ,提出了抗震加固的基本原则 ,可供结构抗震加固时参考     

Finite-difference time-domain simulation of scattering from objectsin continuous random media

A three-dimensional (3D) finite-difference time-domain (FDTD) scheme is introduced to model the scattering from objects in continuous random media. FDTD techniques have been previously applied to scattering from random rough surfaces and randomly placed objects in a homogeneous background, but little has been done to simulate continuous random media with embedded objects where volumetric scattering effects are important. In this work, Monte Carlo analysis is used in conjunction with FDTD to study the scattering from perfectly electrically conducting (PEC) objects embedded in continuous random media. The random medium models under consideration are chosen to be inhomogeneous soils with a spatially fluctuating random permittivities and prescribed correlation functions. The ability of frequency averaging techniques to discriminate objects in this scenarion is also briefly investigated. The simulation scheme described in this work can be adapted and used to help in interpreting the scattered field data from targets in random environments such as geophysical media, biological media, or atmospheric turbulence     

顶封封隔管柱的研制与应用

中原油田近年来注水压力不断升高，井况恶化严重，为此开发了顶封封隔管柱，主要阐述了管柱工况受力特点、结构、工作原理及现场使用效果。经现场较大面积的应用证明，各项性能、技术指标达到了现场要求。     

二过碘酸合银（Ⅲ）钾引发丙类酸甲酯在淀粉上接枝共聚合反应的研究

研究了由二过碘酸合银（Ⅲ）钾（简称Ag(Ⅲ））与可溶性淀粉组成的氧化还原体系，于碱性介质中引发淀粉的接枝共聚合反应，得到高接枝效率的接枝共聚物，测定了引发剂浓度、单体浓度、pH值和反应温度对接枝参数的影响，并探讨了引发机理。     

Overview of ship-design expert systems

Expert systems constitute a branch of artificial intelligence, and their unique characteristics enable computer systems to perform at the level of a human expert by the use of algorithms that can capture domain-specific knowledge. Through an extensive survey of research about ship-design expert systems, we conclude that although development and implementation of expert systems for ship design offer substantial barriers, the shipbuilding industry needs them nonetheless. We examine the major reasons that use of expert systems in this industry has lagged behind. These include the problems of integration with existing computer-aided design systems, problems of knowledge representation and sizable development costs. We discuss in detail some key factors that can lead to the solution of these problems.