Exploring the diagnostic utility of facial composites: Beliefs of guilt can bias perceived similarity between composite and suspect.

Facial composite research has generally focused on the investigative utility of composites—using composites to find suspects. However, almost no work has examined the diagnostic utility of facial composites—the extent to which composites can be used as evidence against a suspect. For example, detectives and jurors may use the perceived similarity of a suspect to a composite as evidence to determine the likelihood of a suspect's guilt. However, research in social cognition and models of cognitive coherence suggest that these similarity judgments may be biased by evaluators' preexisting beliefs of guilt. Two studies examined how preexisting beliefs of guilt influence similarity ratings between a suspect and a facial composite. Study 1 (n = 93) demonstrated that mock-investigators' beliefs in a suspect's guilt inflated their subsequent similarity ratings. Study 2 (n = 49) demonstrated that mock-jurors' beliefs in a defendant's guilt predicted their similarity ratings. These findings highlight a problem of using facial composites as evidence against a suspect, and demonstrate the malleability of similarity judgments. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Adolescent psychopathology: I. Prevalence and incidence of depression and other DSM-III—R disorders in high school students": Correction.

Reports an error in the original article by P. M. Lewinsohn et al ( Journal of Abnormal Psychology, 1993[Feb], Vol 102[1], 133–244). On page 140, in the Total Incidence columns in Table 4, the data for the Attention Deficit row should be switched with that for the Conduct row. (The following abstract of this article originally appeared in record 1993-25780-001.) Data were collected on the point and lifetime prevalences, 1-yr incidence, and comorbidity of depression with other Diagnostic and Statistical Manual of Mental Disorders-III-Revised (DSM-III-R) disorders in a randomly selected sample (n?=?1,710) of high school students at point of entry and at 1-yr follow-up (n?=?1,508). The Schedule for Affective Disorders and Schizophrenia for School-Age Children was used to collect diagnostic information; 9.6% met criteria for a current disorder, more than 33% had experienced a disorder over their lifetimes, and 31.7% of the latter had experienced a 2nd disorder. High relapse rates were found for all disorders, especially for unipolar depression (18.4%) and substance use (15.0%). Female Ss had significantly higher rates at all age levels for unipolar depression, anxiety disorders, eating disorders, and adjustment disorders; male Ss had higher rates of disruptive behavior disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Couple therapy as a treatment for depression: II. The effects of relationship quality and therapy on depressive relapse.

Investigated the effects of behavioral couple therapy, cognitive–behavioral therapy, and their combination on female depression 6 and 12 mo after therapy ended. It was predicted that couples receiving a behavioral couple treatment would be less likely to relapse than those receiving a cognitive–behavioral treatment for the depressed spouse alone. Relapse rates, however, did not discriminate between treatments at any follow-up point. Reductions in husband and wife dysphoria and increases in wife facilitative behavior during therapy predicted recovery. Moreover, high rates of husbands' facilitative behavior at posttest were associated with wife recovery and predicted low levels of depression at the 1-yr follow-up. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding

CD44 is a cell surface receptor for the glycosaminoglycan hyaluronan (HA). Not all CD44-positive cells bind HA, and binding ability is strictly regulated. Three different HA binding states have been defined: inactive, inducible (by certain CD44-specific monoclonal antibodies), and constitutively active. The observation that sets of genetically related cell lines representing different HA binding states showed correlated differences in N-glycosylation of CD44, and that inhibition of N-glycosylation enhanced HA binding (Lesley et al., J. Exp. Med., 182: 431-437, 1995) led us to examine directly whether specific N-glycosylation site modifications were involved in regulating the HA binding function. CD44-negative, -active, and inducible cell lines were stably transfected with mutant constructs in which each of the five N-glycosylation sites of murine CD44 had been separately inactivated. Ability to bind soluble HA was examined over a range of CD44 expression levels. For the active cell line, AKR1, transfectants for all N-glycosylation mutants bound HA as well as did transfectants for wild type CD44. No inhibitory effects of inactivating specific N-glycosylation sites were observed. HA binding was activated when two of the mutant constructs were transfected into a novel CD44-negative inducible cell line. Inactivation of N-glycosylation sites at residues 25 or 120 converted the inducible cell line to constitutively active, whereas inactivation of other sites had little or no effect. Fusion proteins secreted from inactive, inducible, or active cell lines were purified, bound to beads, and assayed for HA binding activity by flow cytometric analysis. Fusion proteins derived from inactive, inducible, and constitutively active cells exhibited three distinguishable "threshold" densities required for HA binding ability. The results imply that the CD44 molecules produced in cells in these three activation states have intrinsic differences in HA binding function. Treatment of the fusion proteins with neuraminidase altered the HA binding state, and glycosylation mutations that affected the phenotype of the inducible cell line lowered the threshold required for HA binding of CD44-immunoglobulin fusion proteins derived from the inducible cell line. Thus, alterations of glycosylation of CD44 itself can affect HA binding ability as manifested by a change in HA binding state.     

Glycerol,glucose and 2-acetoacetoxyethyl methacrylate: Effect on methyl linolenate oxidation and yellowing

The effect of glycerol, glucose and acetoacetoxyethyl methacrylate (AAEM) on autoxidation and yellowing of methyl linolenate has been investigated by nuclear magnetic resonance (NMR) and ultraviolet (UV)-Visible spectroscopies. The extent of autoxidation was determined by measuring the NMR integration of vinylic protons with respect to methoxy protons, an internal standard, as a function of time. The extent of yellowing was determined by measuring the difference in absorbance at 400 nm and 450 nm as a function of time. Glycerol and AAEM showed inhibition of autoxidation, but the most significant effect was observed with AAEM. Glucose enhanced the autoxidation of methyl linolenate. Inhibition of yellowing was observed with all these compounds, especially with glycerol and AAEM.     

Effect of thioanisole and trimethylene sulfide on the oxidation and yellowing of methyl linolenate

The effect of thioanisole and trimethylene sulfide on the autoxidation and yellowing of methyl linolenate has been investigated by nuclear magnetic resonance (NMR) and ultraviolet visible spectroscopy, respectively. The progress of autoxidation was followed by measuring the NMR integration of vinylic protons with respect to methoxy protons, which served as the internal standard, as a function of time. The degree of yellowing was determined by measuring the difference in absorbance at 400 nm and 450 nm as a function of time. Both thioanisole and trimethylene sulfide enhanced the autoxidation of methyl linolenate. Inhibition of yellowing was observed only with trimethylene sulfide.     

Adolescent modeling of parent substance use: The moderating effect of the relationship with the parent.

This study examined a hypothesis derived from social learning theory, that adolescents would be more likely to model the substance use of each parent if they had a relatively good relationship with the parent than if their relationship with that parent was relatively poor. Data from 657 adolescents (51% female; 11 to 15 years of age at the 1st assessment), 357 fathers, and 633 mothers across a 6-year assessment period were used for these analyses. As hypothesized, all adolescents modeled mother's cigarette use and father's marijuana use, older adolescents modeled mother's marijuana use and younger girls and older boys modeled father's alcohol use if they had a relatively good or moderate relationship with that parent but did not model their parent's use if the relationship with that parent was relatively poor. Caution is noted in assuming that relatively good relationships with a parent are always protective. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Impact of distressed and aggressive behavior.

Two studies examined the hypothesis that distressed behavior induces negative emotions in others but also prompts solicitousness and deters aggression. In Study 1, 48 marital dyads rated various behaviors in terms of their feelings and reactions toward a spouse engaging in each behavior. Distressed behavior prompted both negative and solicitous emotions, but deterred hostile reactions. Aggressive behavior prompted negative feelings and hostile and argumentative reactions. In Study 2, 41 couples rated videotaped examples of a woman engaging in distressed, aggressive, or neutral behavior, with variations in verbal content and nonverbal affect. Examples of distressed behavior prompted more negative feelings and more solicitous feelings than neutral behavior. Aggressive examples prompted more negative feelings and hostile reactions. The studies indicate the importance of distinguishing between distressed and aggressive behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)