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排序方式: 共有452条查询结果,搜索用时 15 毫秒
81.
82.
Ida Cariati Roberto Bonanni Gabriele Pallone Cristian Romagnoli Anna Maria Rinaldi Giuseppe Annino Giovanna DArcangelo Virginia Tancredi 《International journal of molecular sciences》2022,23(18)
Whole body vibration (WBV) is well known to exert beneficial effects on multiple tissues, improving synaptic transmission, muscle mass, bone quality, and reducing anxiety and depressive behavior. However, the underlying molecular mechanisms are not yet fully understood, and organs and tissues may respond differently to the vibratory stimulus depending on multiple factors. Therefore, we investigated the WBV effects on the brain and musculoskeletal tissue of 4-month-old young mice, evaluating synaptic plasticity by electrophysiological recordings and tissue organization by histology and histomorphometric analysis. Specifically, WBV protocols were characterized by the same vibration frequency (45 Hz), but different in vibration exposure time (five series of 3 min for the B protocol and three series of 2 min and 30 s for the C protocol) and recovery time between two vibration sessions (1 min for the B protocol and 2 min and 30 s for the C protocol). In addition, immunohistochemistry was conducted to evaluate the expression of fibronectin type III domain-containing protein 5 (FNDC5), as well as that of tissue-specific markers, such as brain-derived neurotrophic factor (BDNF) in brain, myostatin in muscle and collagen I (COL-1) in bone. Our results suggest that the WBV effects depend closely on the type of protocol used and support the hypothesis that different organs or tissues have different susceptibility to vibration. Further studies will be needed to deepen our knowledge of physiological adaptations to vibration and develop customized WBV protocols to improve and preserve cognitive and motor functions. 相似文献
83.
Ida Löscher Anton Axelsson Johanna Vännström Anders Jansson 《Theoretical Issues in Ergonomics Science》2018,19(1):101-117
Introducing automation in a human-machine system changes the tasks performed by human operators. It is difficult to analyse systems for which there are no experienced operators. This issue emerged within a project with the aim to develop a human–machine interface for a highly automated long-haul vehicle. To handle the problem, a formative strategies analysis method with promises to enable desktop analyses through predefined strategy categories was adopted. The method was used to investigate strategies for controlling the future long haul vehicle by conducting workshops with today's drivers. The method was shown to be a valuable asset in eliciting strategies for revolutionary design. 相似文献
84.
Priscila F. de Melo Daneysa L. Kalschne Rosana A. da Silva-Buzanello Joana S. Amaral Alex S. Torquato Marinês P. Corso Heloisa G. Falcão Eliane Colla Elza I. Ida Cristiane Canan 《International Journal of Food Science & Technology》2020,55(1):397-405
The aim of this study was to produce cereal bars (CB) added with tempeh flour (TF) and evaluate the nutritional composition, fatty acids profile, isoflavone content and sensory acceptance. Tempeh was produced from organic soya beans cotyledons fermented by Rhizophus oligosporus followed by freeze-drying and milling in order to obtain the TF. The addition of 10%, 15% and 20% TF to CB resulted in both protein and lipid content increase and a higher polyunsaturated/saturated fatty acids ratio. The content of isoflavone aglycones, the forms considered to have higher biological activity, was higher in TF than in soya bean, which was also reflected in the CB chemical composition. An acceptance test showed that CB added with TF (up to 15%) were sensory accepted. Overall results suggest that the addition of TF as an ingredient in cereal bars allows improving the chemical and functional characteristics of this type of ready-to-eat foods. 相似文献
85.
Pawe Kowalczyk Mateusz Szymczak Magdalena Maciejewska ukasz Laskowski Magdalena Laskowska Ryszard Ostaszewski Grzegorz Skiba Ida Franiak-Pietryga 《International journal of molecular sciences》2021,22(2)
Silver and its nanoparticles (AgNPs) have different faces, providing different applications. In recent years, the number of positive nanosilver applications has increased substantially. It has been proven that AgNPs inhibit the growth and survival of bacteria, including human and animal pathogens, as well as fungi, protozoa and arthropods. Silver nanoparticles are known from their antiviral and anti-cancer properties; however, they are also very popular in medical and pharmaceutical nanoengineering as carriers for precise delivery of therapeutic compounds, in the diagnostics of different diseases and in optics and chemistry, where they act as sensors, conductors and substrates for various syntheses. The activity of AgNPs has not been fully discovered; therefore, we need interdisciplinary research to fulfil this knowledge. New forms of products with silver will certainly find application in the future treatment of many complicated and difficult to treat diseases. There is still a lack of appropriate and precise legal condition regarding the circulation of nanomaterials and the rules governing their safety use. The relatively low toxicity, relative biocompatibility and selectivity of nanoparticle interaction combined with the unusual biological properties allow their use in animal production as well as in bioengineering and medicine. Despite a quite big knowledge on this topic, there is still a need to organize the data on AgNPs in relation to specific microorganisms such as bacteria, viruses or fungi. We decided to put this knowledge together and try to show positive and negative effects on prokaryotic and eukaryotic cells. 相似文献
86.
Siti Hajar Saharudin Jun Haslinda Shariffuddin Noor Ida Amalina Ahamad Nordin 《化学工程与技术》2019,42(9):1757-1763
Bone scaffold is a three‐dimensional structure composed of materials that could enhance bone regeneration. Bone scaffolds were prepared using freeze‐drying by varying the cockle shell powder concentration where sodium alginate acted as matrix. The scaffolds were then characterized by X‐ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, texture analyzer, and liquid displacement method. The bioactivity of the scaffolds was evaluated by immersion into a simulated body fluid solution. Cockle shell powder concentrations affected the bone scaffold characteristics. The increment of the powder concentrations improved the physicochemical properties and bioactivity of the scaffolds. 相似文献
87.
Examined the influence of spatial attention on the retrieval of items from short term memory. 48 participants (aged 18–40 yrs) responded to probe letters after sets of 2, 4, and 6 letters were memorized (S. Sternberg, 1966, 1969). Spatial attention was controlled by central arrow cues and stimuli were presented in a clear or a visually degraded form. Overall RT was shorter for attended than for unattended locations, and shorter for clear than for degraded stimuli. Even though the function relating RT to memory-set size for stimuli in attended locations had a significantly smaller zero-intercept than the function for unattended locations, the slope was unchanged, which suggests that attention did not influence the memory-scanning stage. Visual quality interacted with attention, which suggests that they influenced the same stage of processing, presumably the early visual-encoding stage of processing. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
88.
A new simple technique for aligning the polarisation of a laser diode with the principal axis of a birefringent fibre is described. The angular error of alignment is restricted by the crosstalk of the fibre and the extinction ratio of the polariser, analyser used. 相似文献
89.
K Kusano T Seko S Tanaka Y Shikata T Ando S Ida M Hosokawa T Satoh T Yuzuriha T Horie 《Canadian Metallurgical Quarterly》1996,24(11):1186-1191
We previously showed that a polymorphism for E6123 [(S)-(+)-6- (2-chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5- tetrahydro-8H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a] [1,4]diazepine] metabolism exists only in rhesus monkeys. In the present study, we purified, from rhesus monkey hepatic microsomes, three amido hydrolases that are involved in the metabolic polymorphism. Two forms of amido hydrolase from an extensive metabolizer and one from a poor metabolizer were purified by Q-Sepharose Fast Flow, Red A-agarose, octylamino-Sepharose 4B, and hydroxyapatite-Ultrogel chromatography, after solubilization with Lubrol. The three purified enzymes had the same molecular mass (47 kDa), and their amino-terminal amino acid sequences were identical. The enzymes were different from various known carboxylesterases in terms of substrate specificity, molecular mass, and amino-terminal amino acid sequence. They resembled arylacetamide deacetylase from human hepatic microsomes with respect to molecular mass and amino-terminal amino acid sequence. The KM values of the high and low affinity enzymes in the extensive metabolizer and the sole enzyme in the poor metabolizer were 37.6, 73.0, and 76.5 microM, respectively. The Vmax values were 3312.4, 504.8, and 427.9 pmol/min/mg of protein, respectively. The high affinity enzyme in extensive metabolizer appears to be quite distinct, whereas the low affinity enzyme in extensive metabolizer in similar or identical to the sole enzyme in poor metabolizer. Thus, the metabolic polymorphism in rhesus monkey may depend upon the existence of the high affinity enzyme in extensive metabolizer. 相似文献
90.
Ida De Michelis Agostino Olivieri Stefano Ubaldini Francesco Ferella Francesca Beolchini Francesco Vegliò 《矿业科学技术学报(英文版)》2013,23(5):709-715
This paper deals with gold extraction from a refractory concentrate by chlorine leaching. The process considers a pre-treatment of refractory materials by low temperature oxidation carried out with low oxygen concentration. The oxidized material is treated by leaching with brine. After gold adsorption/reduction onto activated carbon, iron and base metals can be precipitated by NaOH. Roasting tests show the necessity to carry out a thermal pre-treatment at least at 550 °C to obtain a reduction of sulfur and mercury in the material (50% and 90%, respectively). Highest gold extraction yield (around 93%) is obtained in the leaching test performed with material sample treated at 650 °C. This result confirms the necessity to optimize the thermal pre-treatment to improve Au recovery and to reduce chlorine consumption. A comparison with conventional cyanidation confirms that chlorination could be an useful alternative: in fact, gold extraction yield is quite low: 57% in non-pre-treated material and 25% in pre-treatment material. 相似文献