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61.
Ilse Y. Smets Ephraim N. Banadda Jeroen Deurinck Nele Renders Rika Jenn Jan F. Van Impe 《Journal of Process Control》2006,16(3):313-319
For years now, biological wastewater treatment plants rely on activated sludge systems in which a complex ecosystem, constituted mainly of bacteria and protozoa, (bio)degrade the incoming pollutants. Filamentous bulking, a phenomenon in which the filamentous organisms dominate the activated sludge is still a widespread problem in the operation of activated sludge processes with often severe economic and environmental consequences. Image analysis offers promising perspectives for early detection of filamentous bulking because the morphology parameters of the activated sludge respond rather fast to changing process conditions. This paper aims at exploiting this information in black box models to predict the evolution of the sludge volume index (SVI), a laboratory measurement currently exploited to quantify the sludge settleability. More specifically, dynamic ARX models are investigated as a function of organic loading and digital image analysis information (such as the total filament length per image and some representative mean floc shape parameters). The model’s performances are compared on the basis of a squared errors like quality criterion. While the identification results are very promising, the validation of the models on other independently generated data sets, depends on which data set is used for identification. The best performing models have (a combination of) the total filament length, one of the floc elongation parameters and the fractal dimension as inputs. 相似文献
62.
Victoria Ilse Rebekka Scholz Michael Wermann Marcel Naumann Martin S. Staege Steffen Roßner Holger Cynis 《International journal of molecular sciences》2022,23(15)
The triggers for the development of multiple sclerosis (MS) have not been fully understood to date. One hypothesis proposes a viral etiology. Interestingly, viral proteins from human endogenous retroviruses (HERVs) may play a role in the pathogenesis of MS. Allelic variants of the HERV-K18 env gene represent a genetic risk factor for MS, and the envelope protein is considered to be an Epstein–Barr virus-trans-activated superantigen. To further specify a possible role for HERV-K18 in MS, the present study examined the immunogenicity of the purified surface unit (SU). HERV-K18(SU) induced envelope-specific plasma IgG in immunized mice and triggered proliferation of T cells isolated from these mice. It did not trigger phenotypic changes in a mouse model of experimental autoimmune encephalomyelitis. Further studies are needed to investigate the underlying mechanisms of HERV-K18 interaction with immune system regulators in more detail. 相似文献
63.
Hannelore De Maere Sylvie Chollet Erik Claeys Chris Michiels Marlies Govaert Eveline De Mey Hubert Paelinck Ilse Fraeye 《Food and Bioprocess Technology》2017,10(1):131-142
For several years, researchers have studied the formation of zinc protoporphyrin IX in meat, as it is considered to be an important natural colouring agent in dry cured or fermented meat products in the absence of nitrite and/ or nitrate. Until now, however, mainly pork meat is used for these investigations. The goal of this research was to relate in vitro zinc protoporphyrin IX and protoporphyrin IX formation in eight meat sources (chicken, turkey, pork, lamb, beef, veal, horse and porcine liver) to eight intrinsic parameters using partial least squares regression (PLS) analysis. Significant differences in pH, initial metmyoglobin formation, metmyoglobin reduction ability, total heme, zinc chelatase activity, and total iron and zinc concentration between meat sources were found. Water activity, however, was not significantly different between meat sources. Liver tissue and horse meat showed the best ability to form zinc protoporphyrin IX. Formation of protoporphyrin IX was limited in all meat sources. PLS analysis revealed that mainly zinc chelatase activity, followed by total heme, total iron and zinc content, were predominant intrinsic parameters to explain variations in zinc protoporphyrin IX formation. These findings could be important for meat industry in order to establish the production of red coloured nitrite-free meat products. 相似文献
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Reinhard Siegmund-Schultze Volker Remmert Martin Guntau Ilse Jahn Erich Donnert 《NTM》2002,10(1-3):53-64
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NTM is publishing this article with the best wishes on occasion of Dr. Ilse Jahn’s 80th birthday. As biology historian and long-term member of the NTM-Board, she will be celebrating her birthday on February 2nd 2002. This article is a lecture which she held on November 16th, 2000, in Berlin and which was published as Preprint 175 of the Max-Planck-Institute of Historical Sciences: Dörries, Matthias; Daston, Lorraine; Hagner, Michael (Hrsg.):Wissenschaft zwischen Geld und Geist, Berlin 2001, S. 47–55. We would like to express our gratitude for the reprint authorization of this article. 相似文献
68.
B. Maheswaran Mary G. Williams J. Z. Zhang S. Q. Wang C. A. Bonetto Ilse Heyvaert C. Testelin R. S. Markiewicz Bill C. Giessen 《Journal of Superconductivity》1996,9(1):135-141
An SEM and STM study was made of terrace formation in partial melt-regrown EuBa2Cu3O7–. Terraces form above 920°C, well below the bulk melting temperature (1075±10°C). The terrace formation is accompanied by significant grain growth, possibly triggered by a surface-melting transition. Melting occurs in a layer a few monolayers thick, and the highly mobile layers reconstruct into terraced form due to a faceting transition. The terrace growth can be reproduced by a theoretical faceting model. The STM also reveals a finer-scale sinusoidal modulation of the surface, of unknown origin.We thank Dr. J. Krim for permitting us to use the STM and helpful discussions, and Tim Hussey for technical assistance. This work was supported by the NSF under Grant No. DMR-9203258, and one of us (C.T.) was supported by a Lavoisier grant. 相似文献
69.
基于动态贝叶斯网络的听视觉融合情感识别 总被引:1,自引:0,他引:1
在多媒体领域的研究中,对听视觉情感识别,如何融合听视觉情感信息是关键问题.传统的融合方法采用状态同步多流隐马尔可夫模型(Syn_AVHMM),但忽略了音视频情感信息之间的异步关系,从而影响识别结果.为了对听视觉情感信息之间的关联和异步关系进行更准确的描述,提出了一种听视觉状态可以异步,加入异步程度可控的多流动态贝叶斯网络情感识别模型(Asy_DBN),并在 eNERFACE'05 听视觉情感数据库上进行了情感识别实验.实验结果表明,通过调整听视觉状态流之间的异步约束,Asy-DBN 模型可以得到最好的识别结果,六种情感的平均识别率比马尔可夫模型高出 9.88%,为实际应用提供了依据. 相似文献
70.
Merchant ML Powell DW Wilkey DW Cummins TD Deegens JK Rood IM McAfee KJ Fleischer C Klein E Klein JB 《Proteomics. Clinical applications》2010,4(1):84-96
Purpose: The purpose of this study was to address the hypothesis that small vesicular urinary particles known as exosomes could be selectively microfiltered using low protein‐binding size exclusion filters, thereby simplifying their use in clinical biomarker discovery studies. Experimental design: We characterized a microfiltration approach using a low protein binding, hydrophilized polyvinylidene difluoride membrane to easily and efficiently isolate urinary exosomes from fresh, room temperature or 4°C urine, with a simultaneous depletion of abundant urinary proteins. Using LC‐MS, immunoblot analysis, and electron microscopy methods, we demonstrate this method to isolate intact exosomes and thereby enrich for a low abundant urinary proteome. Results: In comparison to other standard methods of exosome isolation including ultracentrifugation and nanofiltration, we demonstrate equivalent enrichment of the exosome proteome with reduced co‐purification of abundant urinary proteins. Conclusion and clinical relevance: In conclusion, we demonstrate a microfiltration isolation method that preserves the exosome structure, reduces contamination from higher abundant urinary proteins, and can be easily implemented into mass spectrometry analysis for biomarker discovery efforts or incorporation into routine clinical laboratory applications to yield higher sample throughput. 相似文献