Synthesis,structural characterization,and antiproliferative/cytotoxic effects of a novel modified poly(maleic anhydride-co-vinyl acetate)/doxorubicin conjugate

Polymer Bulletin - Drug carrier, poly(maleic anhydride-co-vinyl acetate) (MAVA or poly[MA-co-VA]) copolymer, was traditionally synthesized by free radical chain polymerization reaction, in methyl...     

Dyeing,fastness, and cytotoxic properties,and phenolic constituents of Anthemis tinctoria var. tinctoria (Asteraceae)

The present study focused on dyeing, fastness, cytotoxic properties, and phenolic constituents of various types of fabrics including viscose, cotton, wool, and polyester-viscose blended fabrics with different parts of Anthemis tinctoria var. tinctoria. Comparative study was carried out between ethanol and aqueous extracts of stem, flower, and root of the plant in terms of phenolic constituents, cytotoxic activity, and dyeing properties. It was found that the quantity of phenolic constituents of ethanol and aqueous extracts was quite different. All parts of the plant extract show 0% cytotoxicity except ethanol extract of the root. All the extracts exhibit better cytotoxic activity than the standard cancer drug 5-Florouracil. Ethanol and water extracts of A. tinctoria var. tinctoria plant were used to dye fabrics, but only the water extract displayed dyeing properties. Best color strength value (K/S = 9.19) was obtained with aqueous extract of the stem in the presence of alum mordant for cotton fabrics.     

Very fast H2 production from the methanolysis of NaBH4 by metal‐free poly(ethylene imine) microgel catalysts

The polyethyleneimine (PEI) microgels prepared via microemulsion polymerization are protonated by hydrochloric acid treatment (p‐PEI) and quaternized (q‐PEI) via modification reaction with methyl iodide and with bromo alkanes of different alkyl chain lengths such as 1‐bromoethane, 1‐bromobutane, 1‐bromohexane, and 1‐bromooctane. The bare p‐PEI and q‐PEI microgels are used as catalysts directly without any metal nanoparticles for the methanolysis reaction of sodium borohydride (NaBH₄). Various parameters such as the protonation/quaternization reaction on PEI microgels, the amount of catalyst, the amount of NaBH₄, and temperature are investigated for their effects on the hydrogen (H₂) production rate. The reaction of self‐methanolysis of NaBH₄ finishes in about 32.5 min, whereas the bare PEI microgel as catalyst finishes the methanolysis of NaBH₄ in 22 min. Surprisingly, it is found that when the protonated PEI microgels are used as catalyst, the same methanolysis of NaBH₄ is finished in 1.5 min. The highest H₂ generation rate value is observed for protonated PEI microgels (10 mg) with 8013 mL of H₂/(g of catalyst.min) for the methanolysis of NaBH₄. Moreover, activation parameters are also calculated with activation energy value of 23.7 kJ/mol, enthalpy 20.9 kJ/mol, and entropy ?158 J/K.mol. Copyright © 2016 John Wiley & Sons, Ltd.     

A literature review on MHE selection problem: levels,contexts, and approaches

This paper presents a review on selection problem of material handling equipment (MHE) and general equipment used in industry area. The issue on MHE is widely paid attention since MHE has contribution on material, good and product accomplishment. Few methods and softwares have been proposed and developed to select the most appropriate MHE for a complex selection problem. Today’s high diverisity of MHE categories and types influence the generation of many possible choices which leads to the complexity. In this paper, a further discussion in terms of MHE and equipment including three major points namely level of selection, the context of selection problem and the approaches are served to highlight the complex MHE selection according to the number of possible choices provided, to analyse the consideration for the problem context, and to reveal the superior method for complex MHE selection. Forty-two papers collected from the past study are presented asscociating each point of the discussion.     

On debonding of graded thermal barrier coatings

Thermal barrier coatings generally consist of a metallic substrate which is the primary structural component, a metallic bond coat which serves as oxygen diffusion barrier, a very thin layer of thermally grown oxide and a ceramic top coat that provides the main thermal shielding. Homogeneous ceramic coatings as top coats appear to have certain undesirable features such as high residual and thermal stresses, generally low toughness and relatively poor bonding strength. The new concept of compositional grading of the top coat may help to overcome some of these shortcomings by eliminating the material property discontinuities. A common mode of failure in thermal barrier coatings seems to be the debonding of the top coat. In this study the related interface crack problem for a graded ceramic/metal top coat is considered. It is assumed that the thermophysical properties of the top coat continuously vary between that of the bond coat at the top coat-bond coat interface and that of the ceramic at and near the free surface. The main objective of the study is to examine the influence of the material nonhomogeneity parameters and relative dimensions on the stress intensity factors and the crack opening displacements.     

Artificial Neural Networks for Prediction of COVID-19 in Saudi Arabia

In this study, we have proposed an artificial neural network (ANN) model to estimate and forecast the number of confirmed and recovered cases of COVID-19 in the upcoming days until September 17, 2020. The proposed model is based on the existing data (training data) published in the Saudi Arabia Coronavirus disease (COVID-19) situation—Demographics. The Prey-Predator algorithm is employed for the training. Multilayer perceptron neural network (MLPNN) is used in this study. To improve the performance of MLPNN, we determined the parameters of MLPNN using the prey-predator algorithm (PPA). The proposed model is called the MLPNN–PPA. The performance of the proposed model has been analyzed by the root mean squared error (RMSE) function, and correlation coefficient (R). Furthermore, we tested the proposed model using other existing data recorded in Saudi Arabia (testing data). It is demonstrated that the MLPNN-PPA model has the highest performance in predicting the number of infected and recovering in Saudi Arabia. The results reveal that the number of infected persons will increase in the coming days and become a minimum of 9789. The number of recoveries will be 2000 to 4000 per day.     

Microstructure and densification of ZrB2–SiC composites prepared by spark plasma sintering

ZrB₂–SiC composites were prepared by spark plasma sintering (SPS) at temperatures of 1800–2100 °C for 180–300 s under a pressure of 20 MPa and at higher temperatures of above 2100 °C without a holding time under 10 MPa. Densification, microstructure and mechanical properties of ZrB₂–SiC composites were investigated. Fully dense ZrB₂–SiC composites containing 20–60 mass% SiC with a relative density of more than 99% were obtained at 2000 and 2100 °C for 180 s. Below 2120 °C, microstructures consisted of equiaxed ZrB₂ grains with a size of 2–5 μm and α-SiC grains with a size of 2–4 μm. Morphological change from equiaxed to elongated α-SiC grains was observed at higher temperatures. Vickers hardness of ZrB₂–SiC composites increased with increasing sintering temperature and SiC content up to 60 mass%, and ZrB₂–SiC composite containing 60 mass% SiC sintered at 2100 °C for 180 s had the highest value of 26.8 GPa. The highest fracture toughness was observed for ZrB₂–SiC composites containing 50 mass% SiC independent of sintering temperatures.     

Ureteroscopic management of lower ureteral stones: two years'' experience

1. This study was to determine the effects of heat load early in life on thermoregulatory responses and whole blood viscosity of broilers during a subsequent exposure to high environmental temperature later in life. 2. The birds, which had been subjected to exposure to 38 degrees C for 24 h at 5-d-old, served as prior exposure group (group A). Both group A and control group B were exposed to 33 degrees C for 3 h when near marketable weight. 3. On exposure to 33 degrees C, although there were no significant differences in the increases in heat production (HP) between the two groups, abdominal temperature (Ta), temperature of external ear tract (Tee), shank skin temperature (Tss), standing-lying frequency and lying time were lower in group A than in group B. Heart rate (HR) and comb surface temperature (Tcs) did not differ but increased in both groups during exposure to 33 degrees C. Respiration rate (RR) was greater in group A. 4. Blood viscosity decreased markedly in both groups after exposure to 33 degrees C; the decrease was greater in group A. 5. These results suggest that early exposure may promote broilers' ability to cope with the subsequent heat load by altering thermoregulatory physiological responses and behavioural patterns, resulting in an alleviation of heat stress.