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991.
Larimer Mary E.; Lee Christine M.; Kilmer Jason R.; Fabiano Patricia M.; Stark Christopher B.; Geisner Irene M.; Mallett Kimberly A.; Lostutter Ty W.; Cronce Jessica M.; Feeney Maggie; Neighbors Clayton 《Canadian Metallurgical Quarterly》2007,75(2):285
The current study was designed to evaluate the efficacy of a mailed feedback and tips intervention as a universal prevention strategy for college drinking. Participants (N = 1,488) were randomly assigned to feedback or assessment-only control conditions. Results indicated that the mailed feedback intervention had a preventive effect on drinking rates overall, with participants in the feedback condition consuming less alcohol at follow-up in comparison with controls. In addition, abstainers in the feedback condition were twice as likely to remain abstinent from alcohol at follow-up in comparison with control participants (odds ratio = 2.02), and feedback participants were significantly more likely to refrain from heavy episodic drinking (odds ratio = 1.43). Neither gender nor severity of baseline drinking moderated the efficacy of the intervention in these analyses, but more conservative analyses utilizing last-observation carryforward suggested women and abstainers benefited more from this prevention approach. Protective behaviors mediated intervention efficacy, with participants who received the intervention being more likely to use strategies such as setting limits and alternating alcohol with nonalcoholic beverages. Implications of these findings for universal prevention of college drinking are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
992.
Irene G. Cano Sergi Dosta Joan Ramon Miguel Jose Maria Guilemany 《Journal of Materials Science》2007,42(22):9331-9335
Producing nanostructured materials through metastable phases is interesting in the field of ceramic materials. Metastable
phases can be obtained by the Atmospheric Plasma Spray (APS) technique which, is a well-known technique to produce coatings.
The initial powders are melted during the spraying obtaining a homogenized phase due to their solubility in the liquid state.
Afterwards, the molten droplets are quenched in a cooled medium, producing the sought metastable phases. Finally, during material
consolidation, the metastable structure evolves due to a dual structure. A suppression of the grain growth is produced as
a consequence of the immiscibility of both phases in the solid state. Due to their small grain size and uniform structure,
these nanostructured materials exhibit very interesting properties such as higher hardness and toughness. The aim of this
research has been to produce nanostructured Al2O3–TiO2 ceramic powders through APS + quenching route, starting from commercially available micron-sized powders. A complete characterization
of the obtained structures using XRD, SEM, FESEM and EDS has been carried out in the Thermal Spray Center (CPT) of the University
of Barcelona. 相似文献
993.
José A. Carrillo Irene M. Gamba Armando Majorana Chi-Wang Shu 《Journal of Computational Electronics》2002,1(3):365-370
In this work we present preliminary results of a high order WENO scheme applied to a new formulation of the Boltzmann equation (BTE) describing electron transport in semiconductor devices with a spherical coordinate system for the phase velocity space. The problem is two dimensional in the phase velocity space and one dimensional in the physical space, plus the time variable driving to steady states. The new formulation avoids the singularity due to the spherical coordinate system. 相似文献
994.
Evaluation of organochlorine pesticide residues in human serum from an urban and two rural populations in Portugal 总被引:1,自引:0,他引:1
Organochlorine pesticide residues were measured in human serum from an urban and two rural populations in Portugal, in an attempt to evaluate the contamination level of Portuguese population. Serum levels of 12 residues were determined using a validated methodology that included gas chromatography-electron-capture detection. It was made an attempt to point out the differences of contamination between rural and urban populations; and among these, if it could be established a relation with sex and with age of individuals. p,p'DDE, alpha-hexachlorocyclohexane (HCH), p,p'DDD, and beta-HCH were the most frequently identified residues. p,p'DDE concentrations ranged from undetected to 390.5 microg/l in urban samples, and from undetected to 43.5 microg/l and to 171.2 microg/l in both rural samples. Maximum alpha-HCH concentration level was 114.4 microg/l in urban samples, 261.3 and 45.5 microg/l in both rural samples. Mean total DDT levels were always higher than mean total HCH levels. About p,p'DDE, in all three populations, the majority of the results above the limit of quantification were found among female sex. The analysis of different aged groups showed that younger groups continue to reveal contamination. Comparing obtained results with others from Europe, Asia and America, it was observed that Portugal is between the highest levels of contamination. 相似文献
995.
Gómez-Pinto I Marchán V Gago F Grandas A González C 《Chembiochem : a European journal of chemical biology》2003,4(1):40-49
Covalently linked peptide-oligonucleotide hybrids were used as models for studying tryptophan-DNA interactions. The structure and stability of several hybrids in which peptides and oligonucleotides are linked through a phosphodiester bond between the hydroxy group of a homoserine (Hse) side chain and the 3'-end of the oligonucleotide, have been studied by both NMR and CD spectroscopy and by restrained molecular dynamics methods. The three-dimensional solution structure of the complex between Ac-Lys-Trp-Lys-Hse(p3'dGCATCG)-Ala-OH (p=phosphate, Ac=acetyl) and its complementary strand 5'dCGTAGC has been determined from a set of 276 experimental NOE distances and 33 dihedral angle constraints. The oligonucleotide structure is a well-defined duplex that belongs to the B-form family of DNA structures. The covalently linked peptide adopts a folded structure in which the tryptophan side chain stacks against the 3'-terminal guanine moiety, which forms a cap at the end of the duplex. This stacking interaction, which resembles other tryptophan-nucleobase interactions observed in some protein-DNA complexes, is not observed in the single-stranded form of Ac-Lys-Trp-Lys-Hse(p3'dGCATCG)-Ala-OH, where the peptide chain is completely disordered. A comparison with the pure DNA duplex, d(5'GCTACG3')-(5'CGTAGC3'), indicates that the interaction between the peptide and the DNA contributes to the stability of the nucleopeptide duplex. The different contributions that stabilize this complex have been evaluated by studying other nucleopeptide compounds with related sequences. 相似文献
996.
Front Cover: Design of Highly Potent,Dual‐Acting and Central‐Nervous‐System‐Penetrating HIV‐1 Protease Inhibitors with Excellent Potency against Multidrug‐Resistant HIV‐1 Variants (ChemMedChem 8/2018) 下载免费PDF全文
Prof. Dr. Arun K. Ghosh Dr. Kalapala Venkateswara Rao Dr. Prasanth R. Nyalapatla Dr. Satish Kovela Dr. Margherita Brindisi Dr. Heather L. Osswald Dr. Bhavanam Sekhara Reddy Dr. Johnson Agniswamy Yuan‐Fang Wang Dr. Manabu Aoki Shin‐ichiro Hattori Prof. Dr. Irene T. Weber Prof. Dr. Hiroaki Mitsuya 《ChemMedChem》2018,13(8):762-762
997.
998.
Jon González-SánchezMichael Harrison Irene Polo-BlancoJosef Schicho 《Journal of Symbolic Computation》2012,47(3):342-353
It is well known that every Del Pezzo surface of degree 5 defined over a field k is parametrizable over k. In this paper, we give an algorithm for parametrizing, as well as algorithms for constructing examples in every isomorphism class and for deciding equivalence. 相似文献
999.
Irene Lia Schlacht 《Personal and Ubiquitous Computing》2011,15(5):487-489
This paper is an introduction to the following five articles, that have been conceived together as one chapter on habitability
consideration for outer space habitations. Those contributions are made from authors in different fields, cultures and countries
working with the Extreme-Design.eu research group. Projects, theories and requirements are referred to the context of outer
space habitats, where for the love of knowledge, human beings are living under extreme condition. The group purpose is to
apply holistic approach (using both scientific and humanity discipines) towards space habitat design to support human cultural
experience and improve technical reliability. Space Anthropology, Space Design, Space Art and Space Psychology are the established
disciplines here considered to have a bearing on astronaut reliability. With multidisciplinary contributions, natural design
philosophy- and human-centred design, these papers aim of collecting a range of solutions and innovative ideas on how to increase
habitability in space. 相似文献
1000.
The present study focuses on the design and development of an instructional approach to develop oral presentation skills. The theoretical base builds on the social cognitive perspective, and self-regulated learning. The aim of the study is to investigate whether the design of a multimedia-based instructional format - comprising of a standardised multimedia instruction, practical activities and feedback - will enhance oral presentation skills. In the study, the differential effect of three ‘modes of feedback’ on performance has been researched. The results reveal that oral presentation skills did improve significantly after the instruction. The multimedia nature of the design was favoured by all participants. In contrast, no significant impact of feedback was found. Nevertheless, feedback proved to be a useful process that was highly welcomed by participants. 相似文献