Plastic Deformation of Single-Crystal Diamond Nanopillars

Diamond is known to possess a range of extraordinary properties that include exceptional mechanical stability. In this work, it is demonstrated that nanoscale diamond pillars can undergo not only elastic deformation (and brittle fracture), but also a new form of plastic deformation that depends critically on the nanopillar dimensions and crystallographic orientation of the diamond. The plastic deformation can be explained by the emergence of an ordered allotrope of carbon that is termed O8-carbon. The new phase is predicted by simulations of the deformation dynamics, which show how the sp³ bonds of (001)-oriented diamond restructure into O8-carbon in localized regions of deforming diamond nanopillars. The results demonstrate unprecedented mechanical behavior of diamond, and provide important insights into deformation dynamics of nanostructured materials.     

Molecular mechanics analysis of drug-resistant mutants of HIV protease

Drug-resistant mutants of HIV-1 protease limit the long-termeffectiveness of current anti-viral therapy. In order to studydrug resistance, the wild-type HIV-1 protease and the mutantsR8Q, V32I, M46I, V82A, V82I, V82F, I84V, V32I/I84V and M46I/I84Vwere modeled with the inhibitors saquinavir and indinavir usingthe program AMMP. A new screen term was introduced to reproducemore correctly the electron distribution of atoms. The atomicpartial charge was represented as a delocalized charge distributioninstead of a point charge. The calculated protease–saquinavirinteraction energies showed the highly significant correlationof 0.79 with free energy differences derived from the measuredinhibition constants for all 10 models. Three different protonationstates of indinavir were evaluated. The best indinavir modelincluded a sulfate and gave a correlation coefficient of 0.68between the calculated interaction energies and free energiesfrom inhibition constants for nine models. The exception wasR8Q with indinavir, probably due to differences in the solvationenergy. No significant correlation was found using the standardmolecular mechanics terms. The incorporation of the new screencorrection resulted in better prediction of the effects of inhibitorson resistant protease variants and has potential for selectingmore effective inhibitors for resistant virus.     

Gender and ergonomics: a case study on the 'non-formal' work of women nurses

Women's work activities are often characterised by 'non-formal actions' (such as giving support). Gender differences in ergonomics may be due to this peculiarity. We applied the method of organisational congruencies (MOC) to ascertain the 'non-formal' work portion of nurses employed in three hospital units (haematology, emergency room and general medicine) during the three work shifts in a major University Hospital in Rome, Italy. We recorded a total of 802 technical actions performed by nine nurses in 72 h of work. Twenty-six percent of the actions in direct patient's care were communicative actions (mainly giving psychological support) while providing physical care. These 'double actions' are often not considered to be a formal part of the job by hospital management. In our case study, the 'non-formal' work of nurses (psychological support) is mainly represented by double actions while taking physical care of the patients. The dual task paradigm in gender oriented research is discussed in terms of its implications in prevention in occupational health. PRACTITIONER SUMMARY: The main purpose of the study was to assess all the formal and non-formal activities of women in the nursing work setting. Offering psychological support to patients is often not considered to be a formal part of the job. Our case study found that nurses receive no explicit guidelines on this activity and no time is assigned to perform it. In measuring the burden of providing psychological support to patients, we found that this is often done while nurses are performing tasks of physical care for the patients (double actions). The article discusses the significance of non-formal psychological work load of women nurses through double actions from the ergonomic point view.     

Algorithms for Del Pezzo surfaces of degree 5 (construction, parametrization)

It is well known that every Del Pezzo surface of degree 5 defined over a field k is parametrizable over k. In this paper, we give an algorithm for parametrizing, as well as algorithms for constructing examples in every isomorphism class and for deciding equivalence.     

Layered Ceramic Phosphors Based on CaAlSiN3:Eu and YAG:Ce for White Light‐Emitting Diodes

To develop warm‐white light‐emitting diodes via conversion phosphors, blue light‐emitting diodes are generally combined with mixtures of green and red‐emitting phosphor powders. Generally, the phosphors are provided by resin embedded particle dispersions. Such resin‐based solutions cause several drawbacks with respect to LED lifetime and quality. Therefore, it has been investigated whether the red‐emitting nitride phosphor CaAlSiN₃:Eu and the green‐emitting oxidic phosphor YAG:Ce can be cofired to layered ceramic composites. The shrinkage behavior and the composition of the interface in dependence of sintering temperature and the effect of interdiffusion processes at the interface on the luminescence properties were investigated. The formation of secondary phases at the interface in the cofired structures was found to limit the phosphor functionality for the nitride‐based CaAlSiN₃:Eu in such composite ceramics. To counteract this, sacrificial interlayers were introduced to produce multilayered ceramics comprising CaAlSiN₃:Eu and YAG:Ce for LED lighting applications. It is shown for the first time, that it is possible to sinter layered CaAlSiN₃:Eu and YAG:Ce composite ceramics in a pressureless process at moderate sintering temperatures if one uses thin‐film passivated interfaces to reduce luminescence‐disturbing diffusion phenomena. These results demonstrate that diffusion barriers can be suitable means to obtain layered ceramic composites comprising CaAlSiN₃:Eu and YAG:Ce in a pressureless sintering process with good optical properties.     

Space extreme design

This paper is an introduction to the following five articles, that have been conceived together as one chapter on habitability consideration for outer space habitations. Those contributions are made from authors in different fields, cultures and countries working with the Extreme-Design.eu research group. Projects, theories and requirements are referred to the context of outer space habitats, where for the love of knowledge, human beings are living under extreme condition. The group purpose is to apply holistic approach (using both scientific and humanity discipines) towards space habitat design to support human cultural experience and improve technical reliability. Space Anthropology, Space Design, Space Art and Space Psychology are the established disciplines here considered to have a bearing on astronaut reliability. With multidisciplinary contributions, natural design philosophy- and human-centred design, these papers aim of collecting a range of solutions and innovative ideas on how to increase habitability in space.     

A NFC-based pervasive solution for city touristic surfing

Context-aware and pervasive computing applications have increased their number during the last decade, thanks to the development of new communication and mobile technologies. These applications cover a wide spectrum of problems, sectors, scenarios, and environments that aim to build smart environments supporting many kinds of human interactions. Tourism is an important economic sector for many cities and countries and therefore a research area where the development of ubiquitous applications is having a great interest. In this paper, we propose a solution oriented to help the user to find the location of interest points within the city and navigate through them. In this work, we propose the use of mobile phones with the near-field communication technology incorporated and Smart Posters disseminated along the city. Indoor and outdoor locations and navigation are allowed, “where is it?”, “what is it?”, “where am I?”, “what is there around me?” and the remaining hits of locations and navigation paradigms are supported by an easy, cheap, and context-awareness system without the need of hard tasks to the user related to system installation or tailoring.