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991.
992.
Often, in situations of uncertainty in portfolio management, it is difficult to apply the numerical methods based on the linearity principle. When this happens it is possible to use nonnumeric techniques to assess the situations with a nonlinear attitude. One of the concepts that can be used in these situations is the concept of grouping. In the last 30 years, several studies have tried to give good solutions to the problems of homogeneous groupings. For example, we could mention the Pichat algorithm, the affinities algorithms and several studies developed by the authors of this work. In this paper, we use some topological axioms in order to develop an algorithm that is able to reduce the number of elements of the power sets of the related sets by connecting them to the sets that form the topologies. We will apply this algorithm in the grouping of titles listed in the Stock Exchange or in its dual perspective.  相似文献   
993.
Abstract: Laser range sensors are playing an increased role in construction. These devices are used to collect a large number of points from different locations and then, those points are registered in a common framework. This article describes a new procedure for the registration of point clouds, especially suited to the fields of architecture and cultural heritage. Often, in these fields, the registration of point clouds is subject to errors due to the fact that an important number of points do not lie on particular geometric features. In this article, an accurate and efficient approach for 3D data registration based on Iterative Closest Point (ICP) algorithm is proposed, which takes advantage of the color data acquired along with range data. Points suitable for registration are selected according to their local geometry and/or color properties, thus a significant improvement on performance convergence and processing time is obtained. The algorithm performs an automatic, on‐the‐flight estimation of the overlapping region, taking into account possible color differences produced by lighting changes through the measurement process. The proposed approach has been tested on real scanned data from cultural heritage buildings and compared to other approaches, showing a better performance in terms of automation degree, accuracy, and speed.  相似文献   
994.
Over the last couple of years, self-organizing nanotubes based on the dipeptide diphenylalanine have received much attention, mainly as possible building blocks for the next generation of biosensors and as drug delivery systems. One of the main reasons for this large interest is that these peptide nanotubes are believed to be very stable both thermally and chemically. Previously, the chemical and thermal stability of self-organizing structures has been investigated after the evaporation of the solvent. However, it was recently discovered that the stability of the structures differed significantly when the tubes were in solution. It has been shown that, in solution, the peptide nanotubes can easily be dissolved in several solvents including water. It is therefore of critical importance that the stability of the nanotubes in solution and not after solvent evaporation be investigated prior to applications in which the nanotube will be submerged in liquid. The present article reports results demonstrating the instability and suggests a possible approach to a stabilization procedure, which drastically improves the stability of the formed structures. The results presented herein provide new information regarding the stability of self-organizing diphenylalanine nanotubes in solution.  相似文献   
995.
Inflammation, oxidative stress, and obesity   总被引:1,自引:0,他引:1  
Obesity is a chronic disease of multifactorial origin and can be defined as an increase in the accumulation of body fat. Adipose tissue is not only a triglyceride storage organ, but studies have shown the role of white adipose tissue as a producer of certain bioactive substances called adipokines. Among adipokines, we find some inflammatory functions, such as Interleukin-6 (IL-6); other adipokines entail the functions of regulating food intake, therefore exerting a direct effect on weight control. This is the case of leptin, which acts on the limbic system by stimulating dopamine uptake, creating a feeling of fullness. However, these adipokines induce the production of reactive oxygen species (ROS), generating a process known as oxidative stress (OS). Because adipose tissue is the organ that secretes adipokines and these in turn generate ROS, adipose tissue is considered an independent factor for the generation of systemic OS. There are several mechanisms by which obesity produces OS. The first of these is the mitochondrial and peroxisomal oxidation of fatty acids, which can produce ROS in oxidation reactions, while another mechanism is over-consumption of oxygen, which generates free radicals in the mitochondrial respiratory chain that is found coupled with oxidative phosphorylation in mitochondria. Lipid-rich diets are also capable of generating ROS because they can alter oxygen metabolism. Upon the increase of adipose tissue, the activity of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), was found to be significantly diminished. Finally, high ROS production and the decrease in antioxidant capacity leads to various abnormalities, among which we find endothelial dysfunction, which is characterized by a reduction in the bioavailability of vasodilators, particularly nitric oxide (NO), and an increase in endothelium-derived contractile factors, favoring atherosclerotic disease.  相似文献   
996.
A Vehicular Ad hoc Network is a type of wireless ad hoc network that facilitates ubiquitous connectivity between vehicles in the absence of fixed infrastructure. Source based geographical routing has been proven to perform well in unstable vehicular networks. However, these routing protocols leverage beacon messages to update the positional information of all direct neighbour nodes. As a result, high channel congestion or problems with outdated neighbour lists may occur. To this end, we propose a street-aware, Intelligent Beaconless (IB) geographical forwarding protocol based on modified 802.11 Request To Send (RTS)/ Clear To Send frames, for urban vehicular networks. That is, at the intersection, each candidate junction node leverage digital road maps as well as distance to destination, power signal strength of the RTS frame and direction routing metrics to determine if it should elect itself as a next relay node. For packet forwarding between Intersections, on the other hand, the candidate node considers the relative direction to the packet carrier node and power signal strength of the RTS frame as routing metrics to elect itself based on intelligently combined metrics. After designing the IB protocol, we implemented it and compared it with standard protocols. The simulation results show that the proposed protocol can improve average delay and successful packet delivery ratio in realistic wireless channel conditions and urban vehicular scenarios.  相似文献   
997.
A systematic design approach to achieve micropower class AB CMOS transconductors is presented. It includes techniques to get rail-to-rail operation and continuous transconductance tuning, based on floating and Quasi-Floating Gate transistors. Application of the proposed design approach leads to a new family of high-performance power-efficient class AB CMOS transconductors. To illustrate the feasibility of this approach, 12 transconductors derived from this common framework have been designed and fabricated in a 0.5 μm CMOS technology. Measurement results show THD values for 2 V inputs of −56 dB for a static power of 300 μW and silicon area <0.07 mm2.  相似文献   
998.
Through billions of years of evolution and natural selection, biological systems have developed strategies to achieve advantageous unification between structure and bulk properties. The discovery of these fascinating properties and phenomena has triggered increasing interest in identifying characteristics of biological materials, through modern characterization and modeling techniques. In an effort to produce better engineered materials, scientists and engineers have developed new methods and approaches to construct artificial advanced materials that resemble natural architecture and function. A brief review of typical naturally occurring materials is presented here, with a focus on chemical composition, nano‐structure, and architecture. The critical mechanisms underlying their properties are summarized, with a particular emphasis on the role of material architecture. A review of recent progress on the nano/micro‐manufacturing of bio‐inspired hybrid materials is then presented in detail. In this case, the focus is on nacre and bone‐inspired structural materials, petals and gecko foot‐inspired adhesive films, lotus and mosquito eye inspired superhydrophobic materials, brittlestar and Morpho butterfly‐inspired photonic structured coatings. Finally, some applications, current challenges and future directions with regard to manufacturing bio‐inspired hybrid materials are provided.  相似文献   
999.
Abstract

High reliability organizations (HROs) operate in hazardous, fast-paced, and complex environments yet avoid catastrophic accidents. Since the genesis of HRO theory in 1989, interest in HROs has grown beyond hazardous operations to many industries, including health care. This article reviews the literature to determine the extent to which changes made in health care organizations are aligned with HRO theory, and more specifically, with Roberts’ Six Actions, which are based on HRO theory. The results suggest that HRO theory remains of interest to health care organizations. Implications for engineering managers and opportunities for future research are suggested.  相似文献   
1000.
The present work deals with the use of a constraint-handling differential evolution algorithm to solve a nonlinear dynamic optimization problem (NLDOP) with 51 decision variables. A novel mechatronic design approach is proposed as an NLDOP, where both the structural parameters of a non-redundant parallel robot and the control parameters are simultaneously designed with respect to a performance criterion. Additionally, the dynamic model of the parallel robot is included in the NLDOP as an equality constraint. The obtained solution will be a set of optimal geometric parameters and optimal PID control gains. The optimal geometric parameters adjust the dynamic and the kinematic parameters, optimizing then, the link shapes of the robot. The proposed mechatronic design approach is applied to design simultaneously both the mechanical structure of a five-bar parallel robot and the PID controller.  相似文献   
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