PIC16F877单片机在智能站用电源系统中的应用

本文简述了智能站用电源系统的工作原理、构成与功能,介绍了PIC16F877单片机在智能站用电源系统中的应用,并分析了其硬件组成和软件功能。     

中小电视台媒体资产管理系统研究与应用

广播电视行业经过几十年的发展,积累下许多珍贵的多媒体资料,如何充分利用这些资源,一直是广电行业所关注的重点.随着各级电视台非编网络的相继建成与完善,提出了媒体资产管理这一新概念和技术领域,它是对媒体资产进行其寿命期内全面管理的总体解决方案。由于媒体资产管理在构成、特点、需求等方面与常规产业资产管理有较大区别,本文特针对目前绝大多数中小电视台实际情况,研究并提出媒体资产管理的解决方案。     

一种基于序列译码的快速相关攻击算法

快速相关攻击是一种重要的序列密码分析方法。该文提出一种基于卷积码的序列译码的快速相关攻击算法,首先利用特殊的校验方程将线性分组码转化为低码率卷积码,然后用卷积码的序列译码算法恢复出密钥。当记忆长度较大时,该算法显著地降低了中算法的译码复杂度。     

遥测遥控技术及其在钢铁工业中的应用

对我国工业遥测、遥控技术及其在钢铁工业中的应用现状进行了述评。二遥技术作为信息技术的一个分支,在信息时代必将有一个大的发展,本文针对我国的现状指出了其发展方向。     

一类积分方程的近似解

对于一类带参数的积分方程，给出了用退化核逼近非退化核时的显式解，并分别给出了３种条件下的误差估计     

人体压力分布测量及其传感技术

体压分布测量系统是测试病人坐卧时,人体与接触面之间压力的可视化工具.介绍了人体压力分布测量系统的一般结构,对其关键点--传感器技术作了较为详细的叙述.它们分别是电容式压力传感器;用电阻油墨制成的电阻式压力传感器阵列;压电电阻传感器等.有针对的介绍了国外三种典型的人体压力测试产品,Xsensor、Tekscan和FSA;论述了它们的主要特点及优缺点,并对其主要性能作了对比.最后介绍了自行设计的体压分布测量系统,并给出了实测结果.     

氨基二硫代羧酸酯功能化聚氯乙烯树脂的合成及对Au3+的吸附性能

以聚氯乙烯为原料,依次与三乙烯四胺、CS2和C lCH2COONa反应制得氨基二硫代羧酸酯功能化聚氯乙烯树脂;研究了该树脂对Au3 的吸附性能及Au3 浓度、温度和时间对树脂吸附金量的影响。结果表明,25℃时,树脂对Au3 的饱和吸附量达229.3mg/g,树脂对Au3 的吸附过程符合Langmuir和Freundlich等温方程;吸附后的树脂用1mol/L HCl-5%硫脲洗脱时,金脱附率达87.2%。     

Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD+/Sirt3 Pathway in Mesenchymal Stem Cells

In vitro expansion-mediated replicative senescence has severely limited the clinical applications of mesenchymal stem cells (MSCs). Accumulating studies manifested that nicotinamide adenine dinucleotide (NAD⁺) depletion is closely related to stem cell senescence and mitochondrial metabolism disorder. Promoting NAD⁺ level is considered as an effective way to delay aging. Previously, we have confirmed that nicotinamide mononucleotide (NMN), a precursor of NAD⁺, can alleviate NAD⁺ deficiency-induced MSC senescence. However, whether NMN can attenuate MSC senescence and its underlying mechanisms are still incompletely clear. The present study herein showed that late passage (LP) MSCs displayed lower NAD⁺ content, reduced Sirt3 expression and mitochondrial dysfunction. NMN supplementation leads to significant increase in intracellular NAD⁺ level, NAD⁺/ NADH ratio, Sirt3 expression, as well as ameliorated mitochondrial function and rescued senescent MSCs. Additionally, Sirt3 over-expression relieved mitochondrial dysfunction, and retrieved senescence-associated phenotypic features in LP MSCs. Conversely, inhibition of Sirt3 activity via a selective Sirt3 inhibitor 3-TYP in early passage (EP) MSCs resulted in aggravated cellular senescence and abnormal mitochondrial function. Furthermore, NMN administration also improves 3-TYP-induced disordered mitochondrial function and cellular senescence in EP MSCs. Collectively, NMN replenishment alleviates mitochondrial dysfunction and rescues MSC senescence through mediating NAD⁺/Sirt3 pathway, possibly providing a novel mechanism for MSC senescence and a promising strategy for anti-aging pharmaceuticals.     

The Importance of Immunological Disorders in the Pathogenesis of Lichen Sclerosus in Pediatric Patients: A Systematic Review

Lichen sclerosus (LS) is defined as a chronic mucocutaneous inflammatory disease with a localization predominantly to the anus and genitals (vulvar sclerosus (VLS)). Pediatric lichen sclerosus (LS) is a chronic inflammatory skin condition with predilection for the anogenital area that if untreated can lead to scarring. Vulvar LS is characterized by two peaks in incidence: it occurs in prepubertal girls and in postmenopausal women. To date, several mechanisms and risk factors have been proposed in the pathogenesis of pediatric vulvar LS; however, the etiology of this condition is still not fully understood and constitutes a challenge for scientists and clinicians. The presented research aimed to systematically review the existing literature on the pathogenesis of pediatric LS and to identify possible underlying autoimmune mechanisms and molecular networks. The clinical presentation of pediatric lichen sclerosus and available treatment modalities are also presented to acquaint a broader audience with this underdiagnosed and undertreated condition. As a result of our review, we discuss several potential mechanisms, molecules, and pathways that have been recognized in this disease. The purpose of our review was also to summarize what we can induce in further studies, which will ultimately help to identify the mechanism responsible for the disease and aid in the development of new, more effective treatment strategies for diagnosis and treatment by clinicians and researchers.     

Current Knowledge on Interactions of Plant Materials Traditionally Used in Skin Diseases in Poland and Ukraine with Human Skin Microbiota

Skin disorders of different etiology, such as dermatitis, atopic dermatitis, eczema, psoriasis, wounds, burns, and others, are widely spread in the population. In severe cases, they require the topical application of drugs, such as antibiotics, steroids, and calcineurin inhibitors. With milder symptoms, which do not require acute pharmacological interventions, medications, dietary supplements, and cosmetic products of plant material origin are gaining greater popularity among professionals and patients. They are applied in various pharmaceutical forms, such as raw infusions, tinctures, creams, and ointments. Although plant-based formulations have been used by humankind since ancient times, it is often unclear what the mechanisms of the observed beneficial effects are. Recent advances in the contribution of the skin microbiota in maintaining skin homeostasis can shed new light on understanding the activity of topically applied plant-based products. Although the influence of various plants on skin-related ailments are well documented in vivo and in vitro, little is known about the interaction with the network of the skin microbial ecosystem. The review aims to summarize the hitherto scientific data on plant-based topical preparations used in Poland and Ukraine and indicate future directions of the studies respecting recent developments in understanding the etiology of skin diseases. The current knowledge on investigations of interactions of plant materials/extracts with skin microbiome was reviewed for the first time.