Transient and steady states of Gd2Zr2O7 and 2ZrO2∙Y2O3 (ss) interactions with calcium magnesium aluminium silicates

Reactions between calcium magnesium aluminium silicates (CMAS) and Gd₂Zr₂O₇ or 2ZrO₂?Y₂O₃ (ss) are investigated within a temperature range of 1200–1300 °C and for durations of 1 h–100 h. The evolution of CMAS penetration depth in Gd₂Zr₂O₇ and 2ZrO₂?Y₂O₃ (ss) pellets varies considerably depending on the interaction time. A quantitative analysis of the nature and composition of phases observed in stationary conditions (powder/powder interaction) is performed by SEM-FEG coupled with WDS analyses using micro-agglomerated nanoparticles of Gd₂Zr₂O₇ and 2ZrO₂?Y₂O₃. Faster kinetics of the gadolinium-based system are illustrated through an analysis of the morphology of the reaction area and of the resulting CMAS tightness of reaction products. The compositions and quantities of reaction products observed at equilibrium are very similar for the two systems, but transient states are significantly different.     

Searching for potential biomarkers of cisplatin resistance in human ovarian cancer using a label-free LC/MS-based protein quantification method

Platinum-based chemotherapy, such as cisplatin, is the primary treatment for ovarian cancer. However, drug resistance has become a major impediment to the successful treatment of ovarian cancer. To date, the molecular mechanisms of resistance to platinum-based chemotherapy remain unclear. In this study, we applied an LC/MS-based protein quantification method to examine the global protein expression of two pairs of ovarian cancer cell lines, A2780/A2780-CP (cisplatin-sensitive/cisplatin-resistant) and 2008/2008-C13*5.25 (cisplatin-sensitive/cisplatin-resistant). We identified and quantified over 2000 proteins from these cell lines and 760 proteins showed significant expression changes with a false discovery rate of less than 5% between paired groups. Based on the results we obtained, we suggest several potential pathways that may be involved in cisplatin resistance in human ovarian cancer. This study provides not only a new proteomic platform for large-scale quantitative protein analysis, but also important information for discovery of potential biomarkers of cisplatin resistance in ovarian cancer. Furthermore, these results may be clinically relevant for diagnostics, prognostics, and therapeutic improvement for ovarian cancer treatment.     

MCT technology challenges for mass production

Second generation infrared (IR) detectors are now mature at the production level. These detectors are mostly based on HgCdTe (MCT) materials technology. The main second generation detectors at the mass production level are the 288 4 long wave length for most of the European forward-looking infrared (FLIR) and the 480 6 long wave length for the U.S. Army SADA applications. As far as the 288 4 is concerned, SOFRADIR has delivered more than 3000 units already and the market is estimated to be 15,000 units at least! The market is also very large for SADA II units and SOFRADIR has produced them since the end of 1999. Thus, SOFRADIR produces large quantities of mercury cadmium telluride (MCT) detectors and has a unique experience for MCT detectors in mass production. MCT materials technology challenges for mass production concern the main following issues: Quality and reproducibility, MCT wafer size increase, array yield level increase, and the collective manufacturing approach. These issues are discussed in detail in this paper as well as future trends.     

Transferring the calibration of direct solar irradiance to diffuse-sky radiance measurements for CIMEL Sun-sky radiometers

Two types of sunphotometric measurement are considered in this study: direct-Sun irradiance and diffuse-sky radiance. Based on CIMEL CE318 Sun-sky radiometer characteristics, we introduce a gain-corrected solid angle that allows interconverting calibration coefficients of these two types of measurement, thus realizing a "vicarious" radiance calibration. The accuracy of the gain-corrected solid angle depends on the number of available historical calibration records. The method is easy to use, provided that at least one laboratory calibration has been made previously. Examples coming from three distinct CE318 versions belonging to the AERONET/PHOTONS network are presented to provide details on the vicarious calibration method and protocols. From the error propagation analysis and the comparison with laboratory results, the uncertainty of the vicarious radiance calibration is shown to be comparable with the laboratory one, e.g., 3%-5%.     

Use of hydroxytelechelic cis-1,4-polyisoprene (HTPI) in the synthesis of polyurethanes (PUs). Part 1. Influence of molecular weight and chemical modification of HTPI on the mechanical and thermal properties of PUs

New telechelic cis-1,4-polyisoprene oligomers bearing an hydroxyl group at the end of the polyisoprene backbone and possessing controlled molecular weights were used as soft segments in the elaboration of polyurethane elastomers. Besides, the well defined hydroxytelechelic cis-1,4-polyisoprene (HTPI) structure obtained through a controlled methodology, was chemically modified leading to hydrogenated and epoxidized oligomers based polyurethanes. The influence of the structural changes of these precursors on the polyurethanes properties have been studied. Thus, mechanical parameters as well as glass transition and mechanical transition temperature measurements indicated an increase in PUs hardness when the length of soft segment decreases and when the degree of epoxidized and hydrogenated isoprenic moieties increases. Moreover, based on thermogravimetric analysis (TGA), a linear relationship was established between the weight loss in the urethane stage degradation and the amount of hard segments in the PUs. Otherwise, the hydrogenated soft segments were found more thermally stable than the epoxidized and the non modified ones. By comparison with similar investigations developed from commercial oligodienes (PBHT R20 LM^® and EPOL^®), this study mainly showed that the PUs based on hydrogenated hydroxytelechelic cis-1,4-polyisoprenes were more thermally stable and softer than the EPOL^® based analogues.     

Extension of the FDTD Huygens subgridding to frequency dependent media

A wide range of wireless system developments require knowledge of the distribution of electromagnetic fields from various sources in humans. As experimental assessment is ethically unacceptable, high-resolution numerical dosimetry is needed. The finite-difference time-domain method is the most appropriate due to its simplicity and versatility. Reduction in demands on computational resources can be achieved using subgridding techniques. This paper rigorously introduces frequency dependency to one of the most promising subgridding techniques, Huygens subgridding. The validity of the Huygens surface in lossy media, as well as on the physical interface, is intensively studied.     

Photodétecteurs en intégration monolithique sur guides optiques : modélisation et vérifications expérimentales

The authors developed a model on optical guided structures with complex refractive indices, on 9 desktop-computer. This model allows to predict the coupling efficiency of photodetectors monolithically integrated with optical waveguides. An oscillatory behaviour of the absorption coefficient versus the absorbing layer thinkness has been pointed out. Comparisons with experimental resuylts obtained with device made in different laboratories show a good agrement     

Effect of primary amine hydrocarbon chain length for the selective catalytic reduction of NOx from diesel engine exhaust

The effect of increasing primary amine hydrocarbon chain length on the SCR of NO_x from diesel engine exhaust was investigated and compared to ammonia. Methylamine (CH₃NH₂), ethylamine (CH₃CH₂NH₂), propylamine (CH₃CH₂CH₂NH₂) and butylamine (CH₃CH₂CH₂CH₂NH₂) were tested using a 12 cell mini core NH₃ - SCR catalyst cut from a 400 cpsi block. There is a steady decrease in NO_x conversion as the length of the hydrocarbon chain increases (from 50% for methylamine to 26% for butylamine). For the same number of carbons in the amine, primary amines are more active reductants than methyl substituted secondary or tertiary amines. For example, ethylamine (NO_x conversion of 45%) is more active than dimethylamine (NO_x conversion of 34%).Since the amines are reactive in the gas phase in the temperature range of diesel engine exhaust, gas phase conversions were estimated by replacing the mini core SCR catalyst with an equivalent length of quartz beads. There was no smooth transition in gas phase NO and NO_x conversions with increasing hydrocarbon chain length. The results suggest a different mechanism for gas phase reactions depending on the nature of the amine.     

In-situ fabrication of polyacrylate-silver nanocomposite through photoinduced tandem reactions involving eosin dye

A silver-acrylate nanocomposite was prepared using a novel one-pot strategy involving eosin dye as visible sensitizer and an amine derivative as radicals' source. The mechanism highlighted by steady state photolysis and time-resolved absorption spectroscopy lies on the initial formation of a strong ion-pair complex between eosin and Ag⁺. Upon visible irradiation, the excited triplet state of the metal complex efficiently abstracts a hydrogen atom from the amine and produces an α-aminoalkyl radical. In acrylate monomer matrix, such a strong reactive species initiates a free radical photopolymerization and also provides the reduction of the silver cation. Through this ‘in-situ’ fabrication method, the kinetics formation of the nanocomposite and its detailed structural analysis are characterized by UV-visible, real-time FTIR absorption spectroscopy and by transmission electron microscopy.     

Performance characteristics of a new structured packing

A new structured packing using carbon fibres, called Sepcarb^® 4D, is presented. This packing has several attractive properties, such as high voidage (ε=94%) and high effective area (a=420 m² m^?3). These properties are advantageous for packing used as a gas–liquid contactor for separation units. To determine the internal characteristics of this packing, we performed several experiments using a 150-mm-internal-diameter column. Firstly, hydrodynamics experiments were conducted using an air–water counter current flow to determine the pressure drop (for both dry and wet packing) and flooding point. Secondly, the mass transfer efficiency was determined in terms of HETP (height equivalent to theoretical plate) by total reflux experiments with an n-heptane/cyclohexane mixture at atmospheric pressure. Hydrodynamic performance and mass transfer efficiency were compared with those of packings generally used in distillation and absorption.