Effect of Surface Profile Length on the Backscattering Coefficients of Bare Surfaces

The root mean square (rms) height s and autocorrelation length l are commonly used as the surface roughness input parameters to surface scattering models. Whereas it is well known that the surface roughness parameters of a natural soil surface are underestimated with a short surface profile, it is not clear how much the underestimated surface parameters affect the backscattering coefficients of the surface for various incidence angles and polarizations. In this paper, the backscattering coefficients of simulated and measured surface profiles are computed using the integral equation method and analyzed to answer this question. A 4000lmacr-long rough surface is generated numerically, where lmacr is the true correlation length of the surface, and the backscattering coefficients of the surface are computed and analyzed for various conditions. The rms error of the backscattering coefficient at a medium range of incidence angles is less than 1.5 dB for vv-polarization and 0.5 dB for hh-polarization if the profile length is larger than 5lmacr for a surface with ks=1.0, kl=10.0, and epsiv _r=(10.0,2.0). Similar results are obtained from numerous simulations with various roughness conditions and various wavelengths. It is also shown that the rms error of the backscattering coefficients between 5- and 1-m-long measured surface profiles is 1.7 dB for vv-polarization and 0.5 dB for hh-polarization at a medium range of incidence angle (15deglesthetasles70deg), whereas the surface roughness parameters are significantly reduced from 2.4 to 1.5 cm for the rms height s and from 35.1 to 10.0 cm for the autocorrelation length l     

Study of pyrolysis kinetics of Alberta oil sand by thermogravimetric analysis

The kinetics of the thermal decomposition of Alberta oil sand has been investigated by thermogravimetric analysis (TGA) for the study of oil sand pyrolysis characteristics. The TGA experiments were carried out at four different heating rates of 10, 20, 30, 40 °C/min up to 900 °C to verify weight variation and reaction temperature. The activation energy of the thermal decomposition of Alberta oil sand obtained from the kinetic analysis was similar to that of the previous researches. Also, bitumen was extracted by solvent (toluene, THF (tetrahydrofuran)) and analyzed. Extracted bitumen was analyzed by using proximate analysis, ultimate analysis, heavy metal analysis, heating value, asphaltenes, API, SIMDIS, density, TLC, and molecular weight. The analyses of the extracted bitumen were similar to those of heavy residue.     

A study of fluid dynamics parameters for prediction of obstructive sleep apnea

Obstructive sleep apnea (OSA) is a syndrome characterized by the repetitive episodic collapse of the upper airway. The purpose of this study is to investigate the fluid dynamic parameters for the prediction of obstructive sleep apnea in the upper airway before and after setback surgery. Here, we analyzed the flow phenomena of inspiration and expiration in obstructive sleep apnea patients. The modeling of the upper airway was performed with facial 3 dimensional facial computed tomography images (3D facial CT). We used timedependent value for boundary conditions. The changes of pressure were studied with 3D facial CT taken both before and after the setback surgery. Further, it was found that the correlation between PSG data and non-dimensional pressure drop can be used to predict the severity of OSA. In all 6 patients except for patient 1, the average values of the non-dimensional pressure drops and PSG clinical data are inversely related. For each patient, the lower the pressure drop is, the higher the PSG values will be.     

A thyristor-only input ESD protection scheme for CMOS RF ICs

We propose an input protection scheme composed of thyristor devices only avoiding usage of a clamp NMOS device to minimize the area consumed by an input pad structure in CMOS RF ICs. For this purpose, we suggest low-voltage triggering thyristor protection device structures assuming usage of standard CMOS processes, and attempt an in-depth comparison study with a conventional thyristor protection scheme incorporating a clamp NMOS device in the input pad. The comparison study mainly focuses on robustness against the human body model electrostatic discharge (HBM ESD) in terms of peak voltages applied to gate oxides in an input buffer and lattice heating inside protection devices based on DC and mixed-mode transient analyses utilizing a 2-dimensional device simulator. We constructed an equivalent circuit for the input HBM test environment of the CMOS chip equipped with the input ESD protection devices, and by executing mixed-mode simulations including up to four protection devices and analyzing the results for five different test modes, we attempt a detailed analysis on the problems which can occur in real HBM tests. We figure out strength of the proposed thyristor-only protection scheme, and suggest guidelines relating the design of the protection devices and circuits.     

Interleukin-34-CSF1R Signaling Axis Promotes Epithelial Cell Transformation and Breast Tumorigenesis

IL-34 has been recently identified as a ligand for CSF1R that regulates various cellular processes including cell proliferation, survival, and differentiation. Although the binding of IL-34 to CSF1R modulates several cancer-driving signaling pathways, little is known about the role of IL-34/CSF1R signaling in breast cancer. Herein, we report that IL-34 induces epithelial cell transformation and breast tumorigenesis through activation of MEK/ERK and JNK/c-Jun pathways. IL-34 increased the phosphorylation of MEK1/2, ERK1/2, JNK1/2, and c-Jun through CSF1R in mouse skin epidermal JB6 C141 cells and human breast cancer MCF7 cells. IL-34 enhanced c-Fos and c-Jun promoter activity, resulting in increased AP-1 transactivation activity in JB6 Cl41 and MCF7 cells. Moreover, PIN1 enhanced IL-34-induced phosphorylation of MEK1/2, ERK1/2, JNK1/2, and c-Jun in JB6 Cl41 and MCF7 cells. Inhibition of PIN1 using juglone prevented the IL-34-induced transformation of JB6 C141 cells. Similarly, silencing of PIN1 reduced the IL-34-induced tumorigenicity of MCF7 cells. Consistent with these results, the synergistic model showed that treatment with juglone suppressed the IL-34-induced growth of tumors formed by 4T1 cells in BALB/c mice. Our study demonstrates the role of IL-34-induced MEK/ERK and JNK/c-Jun cascades in breast cancer and highlights the regulatory role of PIN1 in IL-34-induced breast tumorigenesis.     

Synthesis of LiNi1/3Co1/3Mn1/3O2 cathode materials by using a supercritical water method in a batch reactor

LiNi_1/3Co_1/3Mn_1/3O₂ and LiCoO₂ cathode materials were synthesized by using a supercritical water (SCW) method with a metal salt solution in a batch reactor. Stoichiometric LiNi_1/3Co_1/3Mn_1/3O₂ was successfully synthesized in a 10-min reaction without calcination, while overlithiated LiCoO₂ (Li_1.15CoO₂) was synthesized using the batch SCW method. The physical properties and electrochemical performances of LiNi_1/3Co_1/3Mn_1/3O₂ were compared to those of Li_1.15CoO₂ by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and charge/discharge cycling tests. The XRD pattern of LiNi_1/3Co_1/3Mn_1/3O₂ was found to be similar to that of Li_1.15CoO₂, showing clear splitting of the (0 0 6)/(1 0 2) and (1 0 8)/(1 1 0) peak pairs as particular characteristics of the layered structure. In addition, both cathode powders showed good crystallinity and phase purity, even though a short reaction time without calcination was applied to the SCW method. The initial specific discharge capacities of the Li_1.15CoO₂ and LiNi_1/3Co_1/3Mn_1/3O₂ powders at a current density of 0.24 mA/cm² in 2.5-4.5 V were 149 and 180 mAh/g, and their irreversible capacity loss was 20 and 17 mAh/g, respectively. The discharge capacities of the Li_1.15CoO₂ and LiNi_1/3Co_1/3Mn_1/3O₂ powders decreased with cycling and remained at 108 and 154 mAh/g after 30 cycles, which are 79% and 89% of the initial capacities. Compared to the overlithiated LiCoO₂ cathode powders, the LiNi_1/3Co_1/3Mn_1/3O₂ cathode powders synthesized by SCW method had better electrochemical performances.     

Molecular structure of bent-shaped liquid crystal dimers

Liquid crystalline behavior of dimesogenic compounds opens a new area of research in liquid crystals science. The term ‘dimesogenic compounds’ describes thermotropic compounds consisting of two mesogenic units linked through a central spacer such as polymethylene and oligosiloxyl groups. The two mesogenic units may or may not be identical. When they are identical, they are occasionally called twin or siamese compounds.     

Development of spatial water resources vulnerability index considering climate change impacts

This study developed a new framework to quantify spatial vulnerability for sustainable water resources management. Four hydrologic vulnerability indices - potential flood damage (PFDC), potential drought damage (PDDC), potential water quality deterioration (PWQDC), and watershed evaluation index (WEIC) - were modified to quantify flood damage, drought damage, water quality deterioration, and overall watershed risk considering the impact of climate change, respectively. The concept of sustainability in the Driver-Pressure-State-Impact-Response (DPSIR) framework was applied in selecting all appropriate indicators (criteria) of climate change impacts. In the examination of climate change, future meteorological data was obtained using CGCM3 (Canadian Global Coupled Model) and SDSM (Statistical Downscaling Model), and future stream run-off and water quality were simulated using HSPF (Hydrological Simulation Program — Fortran). The four modified indices were then calculated using TOPSIS, a multi-attribute method of decision analysis. As a result, the ranking obtained can be changed in consideration of climate change impacts. This study represents a new attempt to quantify hydrologic vulnerability in a manner that takes into account both climate change impacts and the concept of sustainability.     

Protease Inhibitors from Plants with Antimicrobial Activity

Antimicrobial proteins (peptides) are known to play important roles in the innate host defense mechanisms of most living organisms, including plants, insects, amphibians and mammals. They are also known to possess potent antibiotic activity against bacteria, fungi, and even certain viruses. Recently, the rapid emergence of microbial pathogens that are resistant to currently available antibiotics has triggered considerable interest in the isolation and investigation of the mode of action of antimicrobial proteins (peptides). Plants produce a variety of proteins (peptides) that are involved in the defense against pathogens and invading organisms, including ribosome-inactivating proteins, lectins, protease inhibitors and antifungal peptides (proteins). Specially, the protease inhibitors can inhibit aspartic, serine and cysteine proteinases. Increased levels of trypsin and chymotrypsin inhibitors correlated with the plants resistance to the pathogen. Usually, the purification of antimicrobial proteins (peptides) with protease inhibitor activity was accomplished by salt-extraction, ultrafiltration and C₁₈ reverse phase chromatography, successfully. We discuss the relation between antimicrobial and anti-protease activity in this review. Protease inhibitors from plants potently inhibited the growth of a variety of pathogenic bacterial and fungal strains and are therefore excellent candidates for use as the lead compounds for the development of novel antimicrobial agents.