Does green tea affect postprandial glucose,insulin and satiety in healthy subjects: a randomized controlled trial

Background  

Results of epidemiological studies have suggested that consumption of green tea could lower the risk of type 2 diabetes. Intervention studies show that green tea may decrease blood glucose levels, and also increase satiety. This study was conducted to examine the postprandial effects of green tea on glucose levels, glycemic index, insulin levels and satiety in healthy individuals after the consumption of a meal including green tea.     

The Influence of Strontium on Bone Tissue Metabolism and Its Application in Osteoporosis Treatment

Osteoporosis is a chronic disease characterized by low bone mass caused by increased bone turnover and impaired bone microarchitecture. In treatment, we use antiresorptive or anabolic drugs, which usually have a unidirectional effect, i.e., they inhibit the activity of osteoclasts or stimulate the effect of osteoblasts. Strontium ranelate is an anti-osteoporosis drug with a unique mechanism of action (used primarily in postmenopausal women). Unlike other medicines, it has a multidirectional effect on bone tissue, intensifying osteoblastogenesis while inhibiting osteoclastogenesis. It turns out that this effect is demonstrated by strontium ions, an element showing physical and chemical similarity to calcium, the basic element that builds the mineral fraction of bone. As a result, strontium acts through the calcium-sensing receptor (CaSR) receptor in bone tissue cells. In recent years, there has been a significant increase in interest in the introduction of strontium ions in place of calcium ions in ceramics used as bone replacement materials for the treatment of bone fractures and defects caused by osteoporosis. The aim of this study was to summarize current knowledge about the role of strontium in the treatment of osteoporosis, its effects (in various forms), and the ways in which it is administered.     

Involving domain experts in assistive technology research

Teams engaging in assistive technology research should include expertise in the domain of disability itself, in addition to other areas of expertise that are more typical in human–computer interaction (HCI) research, such as computer science and psychology. However, unexpected problems can arise when HCI researchers do not adequately plan the involvement of domain experts in a research project. Although many research teams have included domain experts when designing assistive technologies, there has been little work published on how to best involve these experts in the research process. This paper is a first step towards filling that void. Based on the authors’ own experiences involving domain experts in research, as well as those documented in the literature, five types of domain experts and three broad roles that domain experts can play are identified, and five guidelines for their involvement are presented. This analysis will be useful to anyone in the assistive technology and universal accessibility communities, especially those who are in the early stages of conducting research in this area. It is intended to lay the foundation of best practices for involving domain experts in assistive technology research.     

Initial Stages of Sintering of Alumina by Thermo-Optical Measurements

The behavior of nanostructured and submicrometer α-Al₂O₃ powders during the initial stages of field-assisted sintering technique (FAST), conventional, and microwave sintering was investigated using the laser-flash technique for thermo-optical measurements (TOM). An enhanced neck formation due to surface diffusion at very early stages of sintering was found in FAST samples. No significant difference due to heating rate has been found in these various samples.     

Adsorption on charcoal sorbents of the nucleic acids from the blood plasma of leukemia patients and from the ascitic fluid of mice with lymphoma NK/Ly

Using 3H-thymidine, 14C-orotic acid and ethidium bromide identification of the nucleic acid double-stranded structures from biological fluids and the method of hemocarboperfusion the data are obtained on the active and irreversible adsorption of nucleic acids and nucleoproteins from plasma of leukaemic patients and ascitic fluid of mice with lymphoma NK/Ly.     

Magnetic resonance studies of cement based materials in inhomogeneous magnetic fields

Single-sided magnets give hope that Nuclear Magnetic Resonance (NMR) might in future be used for in situ characterisation of hydration and water transport in the surface layers of concrete slabs. Towards that end, a portable NMR-MOUSE (MObile Universal Surface Explorer) has been used to follow the hydration of gypsum based plaster, a Portland cement paste and concrete mortar. The results compare favourably to those obtained using a standard laboratory bench-top spectrometer. Further, stray field imaging (STRAFI) based methods have been used with embedded NMR detector coils to study water transport across a mortar/topping interface. The measured signal amplitudes are found to correlate with varying sample conditions.     

Characterization and Quantification of Selenoprotein P: Challenges to Mass Spectrometry

Selenoprotein P (SELENOP) is an emerging marker of the nutritional status of selenium and of various diseases, however, its chemical characteristics still need to be investigated and methods for its accurate quantitation improved. SELENOP is unique among selenoproteins, as it contains multiple genetically encoded SeCys residues, whereas all the other characterized selenoproteins contain just one. SELENOP occurs in the form of multiple isoforms, truncated species and post-translationally modified variants which are relatively poorly characterized. The accurate quantification of SELENOP is contingent on the availability of specific primary standards and reference methods. Before recombinant SELENOP becomes available to be used as a primary standard, careful investigation of the characteristics of the SELENOP measured by electrospray MS and strict control of the recoveries at the various steps of the analytical procedures are strongly recommended. This review critically discusses the state-of-the-art of analytical approaches to the characterization and quantification of SELENOP. While immunoassays remain the standard for the determination of human and animal health status, because of their speed and simplicity, mass spectrometry techniques offer many attractive and complementary features that are highlighted and critically evaluated.