Muss sich das Wirtschaftsinformatik-Curriculum unter dem Gesichtspunkt „Lebenslanges Lernen“ weiterentwickeln?

Ohne Zusammenfassung     

Protein and Metabolite Analysis Reveals Permanent Induction of Stress Defense and Cell Regeneration Processes in a Tobacco Cell Suspension Culture

The secretome of a tobacco cell suspension culture was investigated by a combined proteomic and metabolomic approach. Protein analysis from 2-DE gels led to identification of 32 out of 60 spots from culture medium. Identified proteins were mainly involved in stress defence and cell regeneration processes. Among them three putative new isoforms, e.g. for chitinase, peroxidase and β-1,4-xylosidase were identified, not yet present in available protein databases for the genus Nicotiana. GC-MS analysis of time course experiments revealed significant changes for metabolites involved in energy transport, signalling and cell development. Among them, the most significant increase was found for putrescine in the medium of cultures entering the exponential phase. Results showed strong abundance of stress associated proteins and metabolites in the absence of elicitors or additional stress treatments.     

Topological design,routing and capacity dimensioning for ISL networks in broadband LEO satellite systems

This paper considers the network design of intersatellite link (ISL) networks in broadband LEO satellite systems, where the major challenge is the topology dynamics. First, a general method to design convenient ISL topologies for connection‐oriented operation is presented, and a reference topology for numerical studies is derived. A permanent virtual topology is then defined on top of the orbiting physical one, thus forming a framework for discrete‐time dynamic traffic routing. On this basis, heuristic and optimization approaches for the combined routing and dimensioning task, operating on discrete time steps, are presented and their performance is numerically compared. It is shown that minimizing the worst‐case link capacity is an appropriate target function, which can be formulated as linear optimization problem with linear constraints. Using linear programming (LP) techniques, the dimensioning results are clearly better than with simple heuristic approaches. Copyright © 2001 John Wiley & Sons, Ltd.     

Properties of high-temperature PEFC Celtec-P 1000 MEAs in start/stop operation mode

This paper aims at the comparison of two differently operated Celtec^®-P 1000 MEAs: one MEA is operated in a start/stop cycling mode (12 h operation at 160 °C followed by 12 h shutdown), the other MEA is continuously operated at 160 °C. We demonstrate more than 6000 h total operation time with more than 240 start/stop cycles, while the test is still ongoing. The degradation rate is 0.2 mV cycle⁻¹ or 11 μV h⁻¹ on a time basis. The continuously operated MEA is operated more than 6000 h with a degradation rate of approximately 5 μV h⁻¹. Through separation of the individual cathodic loss terms, a detailed insight into the doubled time-based degradation rate under start/stop cycling conditions could be given. Both Ohmic resistances and oxygen reduction overpotentials are basically identical in MEAs under continuous and start/stop cycling operation. In the start/stop cycled MEA, however, significantly increased cathodic mass transport overpotentials are observed as a result of enhanced corrosion of the cathode catalyst support, which confirms the generally discussed reverse-current mechanism under start/stop cycling conditions. Results from a newly developed MEA demonstrate that this mechanism can successfully be mitigated through improvement of the materials used in the MEA.     

Higher accumulation of polybrominated diphenyl ethers in infants than in adults

Pooled serum samples collected from 8132 residents in 2002/ 03 and 2004/05 were analyzed to assess human polybrominated diphenyl ether (PBDE) concentrations from specified strata of the Australian population. The strata were defined by age (0-4 years, 5-15 years, < 16 years, 16-30 years, 31-45 years, 46-60 years, and > 60 years); region; and gender. For both time periods, infants and older children had substantially higher PBDE concentrations than adults. For samples collected in 2004/ 05, the mean +/- standard deviation sigmaPBDE (sum of the homologue groups for the mono-, di-, tri-, tetra-, penta-, hexa-, hepta-, octa-, nona-, and deca-BDEs) concentrations for 0-4 and 5-15 years were 73 +/- 7 and 29 +/- 7 ng g(-1) lipid, respectively, while for all adults > 16 years, the mean concentration was lower at 18 +/- 5 ng g(-1) lipid. A similar trend was observed for the samples collected in 2002/03, with the mean sigmaPBDE concentration for children < 16 years being 28 +/- 8 ng g(-1) lipid and for the adults >16 years, 15 +/- 5 ng g(-1) lipid. No regional or gender specific differences were observed. Measured data were compared with a model that we developed to incorporate the primary known exposure pathways (food, air, dust, breast milk) and clearance (half-life) data. The model was used to predict PBDE concentration trends and indicated that the elevated concentrations in infants were primarily due to maternal transfer and breast milk consumption with inhalation and ingestion of dust making a comparatively lower contribution.     

Ab initio and in situ comparison of caffeine, triclosan, and triclocarban as indicators of sewage-derived microbes in surface waters

Three organic wastewater compounds (OWCs) were evaluated in theory and practice for their potential to trace sewage-derived microbial contaminants in surface waters. The underlying hypothesis was that hydrophobic OWCs outperform caffeine as a chemical tracer, due to their sorptive association with suspended microorganisms representing particulate organic carbon (POC). Modeling from first principles (ab initio) of OWC sorption to POC under environmental conditions suggested an increasing predictive power: caffeine (0.2% sorbed) < triclosan (9-60%; pH 6-9) < triclocarban (76%). Empirical evidence was obtained via analysis of surface water from three watersheds in a rural-to-urban gradient in Baltimore, MD. Mass spectrometric OWC detections were correlated to microbial plate counts for 40 monitoring sites along 14 streams, including multiple chronic sewage release sites and the local wastewater treatment plant. Consistent with ab initio calculations, correlation analyses of 104 observations for fecal coliforms, enterococci, and Escherichia coli in natural surface waters showed that the particle-active antimicrobials triclosan and triclocarban (R2 range, 0.45-0.55) were indeed superior to caffeine (0.16-0.37) for tracking of microbial indicators. It is concluded that chemical monitoring of microbial risks is more effective when using hydrophobic OWCs such as triclosan and triclocarban in place of, or in conjunction with, the traditional marker caffeine.     

The development and evaluation of microstructured reactors for the water gas shift and preferential oxidation reactions in the 5 kW range

5 kW_el One-Stage Water Gas Shift (WGS) and Preferential Oxidation (PROx) reactors were designed and evaluated for the clean-up of surrogate diesel reformate. For the WGS reactor, CO conversions of up to 95% were attained using typical surrogate synthetic diesel reformate. The PROx reactor was capable of converting a feed concentration of 1.0 mol% CO to 20 ppm. Load changes for both reactors could be carried out without significant overshoots of carbon monoxide.