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排序方式: 共有2691条查询结果,搜索用时 15 毫秒
61.
Edin Alagic Kristine Spildo Arne Skauge Jonas Solbakken 《Journal of Petroleum Science and Engineering》2011,78(2):220-227
Injection of brine with lower salinity than the connate brine has proven to give a moderate increase in oil recovery in sandstones. Recent research has shown that this process will significantly benefit from introducing surfactant optimised for low salinity environment.The mechanisms underlying increased recovery by low salinity brine injection are not yet fully understood. However, research to date suggests that they are related to complex crude oil/brine/rock interactions. With this in mind, the present paper investigates primarily how the extent of oil recovery from Berea sandstones subjected to long term exposure of crude oil is influenced by (1) low salinity water injection and (2) combined process low salinity water injection with surfactant flooding.Core displacement tests were conducted on four Berea cores (30 cm), two in a natural state and two that had been subject to extensive crude oil ageing at high temperature. Results obtained from different flooding steps are discussed in terms of oil recovery and effluent properties including turbidity, pH- and ion analysis (Na+, Mg2+, Ca2+). The results effectively illustrate that oil recoveries from the aged cores are higher during both low salinity water injection and low salinity water injection combined with surfactant flooding. An assessment of how tertiary oil recovery in aged and unaged cores varies with surfactant concentration is also presented.Effluent ion analysis from low salinity water floods showed that Mg2+ ions were strongly retained in the aged core while Ca2+ ions were being produced from both aged and unaged cores. The latter was attributed mainly to calcite dissolution. Results obtained from pressure profiles, effluent ion analysis and turbidity tests suggest higher production and elution of fine particles from the unaged core. 相似文献
62.
Jonas Baumann Christian Krnig Theresa Staufer Christopher Schlesiger Oliver Schmutzler Florian Grüner Wolfgang Malzer Birgit Kanngießer 《International journal of molecular sciences》2022,23(9)
Trace elements, functionalized nanoparticles and labeled entities can be localized with sub-mm spatial resolution by X-ray fluorescence imaging (XFI). Here, small animals are raster scanned with a pencil-like synchrotron beam of high energy and low divergence and the X-ray fluorescence is recorded with an energy-dispersive detector. The ability to first perform coarse scans to identify regions of interest, followed by a close-up with a sub-mm X-ray beam is desirable, because overall measurement time and X-ray dose absorbed by the (biological) specimen can thus be minimized. However, the size of X-ray beams at synchrotron beamlines is usually strongly dependent on the actual beamline setup and can only be adapted within specific pre-defined limits. Especially, large synchrotron beams are non-trivial to generate. Here, we present the concept of graphite-based, convex reflection optics for the one-dimensional enlargement of a 1 mm wide synchrotron beam by a factor of 5 to 10 within a 1 m distance. Four different optics are tested and characterized and their reflection properties compared to ray tracing simulations. The general shape and size of the measured reflection profiles agree with expectations. Enhancements with respect to homogeneity and efficiency can be expected with improved optics manufacturing. A mouse phantom is used for a proof-of-principle XFI experiment demonstrating the applicability of coarse and fine scans with the suggested optics design. 相似文献
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64.
Jonas Feldheim Almuth F. Kessler Julia J. Feldheim Ellina Schulz David Wend Lazaros Lazaridis Christoph Kleinschnitz Martin Glas Ralf-Ingo Ernestus Sebastian Brandner Camelia M. Monoranu Mario Lhr Carsten Hagemann 《International journal of molecular sciences》2022,23(9)
Glioblastoma leads to a fatal course within two years in more than two thirds of patients. An essential cornerstone of therapy is chemotherapy with temozolomide (TMZ). The effect of TMZ is counteracted by the cellular repair enzyme O6-methylguanine-DNA methyltransferase (MGMT). The MGMT promoter methylation, the main regulator of MGMT expression, can change from primary tumor to recurrence, and TMZ may play a significant role in this process. To identify the potential mechanisms involved, three primary stem-like cell lines (one astrocytoma with the mutation of the isocitrate dehydrogenase (IDH), CNS WHO grade 4 (HGA)), and two glioblastoma (IDH-wildtype, CNS WHO grade 4) were treated with TMZ. The MGMT promoter methylation, migration, proliferation, and TMZ-response of the tumor cells were examined at different time points. The strong effects of TMZ treatment on the MGMT methylated cells were observed. Furthermore, TMZ led to a loss of the MGMT promoter hypermethylation and induced migratory rather than proliferative behavior. Cells with the unmethylated MGMT promoter showed more aggressive behavior after treatment, while HGA cells reacted heterogenously. Our study provides further evidence to consider the potential adverse effects of TMZ chemotherapy and a rationale for investigating potential relationships between TMZ treatment and change in the MGMT promoter methylation during relapse. 相似文献
65.
66.
Volker Maier Christian Huber 《Journal für Verbraucherschutz und Lebensmittelsicherheit》2010,22(6):217-223
Eine Besonderheit der natürlichen Sü?stoffe aus Stevia rebaudiana soll ihre vorteilhafte pharmakologische Wirkung sein. In der wissenschaftlichen Literatur wird immer wieder ein Einfluss
auf den menschlichen Blutzuckergehalt und den Blutdruck genannt. Dies w?re ein Novum: Ein Sü?ungsmittel mit Heilwirkung. 相似文献
67.
Soran Shwan Louise Olsson Magnus Skoglundh Jonas Jansson 《American Institute of Chemical Engineers》2015,61(1):215-223
The focus of this work is to investigate whether a previously developed microkinetic deactivation model for hydrothermally treated Fe‐BEA as NH3‐SCR catalyst can be applied to describe chemical deactivation of Fe‐BEA due to phosphorous exposure. The model describes the experiments well for Fe‐BEA before and after phosphorous exposure by decreasing the site density, representing deactivation of sites due to formation of metaphosphates blocking the active iron sites, while the kinetic parameters are kept constant. Furthermore, the results show that the activity for low‐temperature selective catalytic reduction (SCR) is very sensitive to loss of active monomeric iron species due to phosphorous poisoning compared to high‐temperature SCR. Finally, the ammonia inhibition simulations show that exposure to phosphorous may affect the internal transport of ammonia between ammonia storage sites buffering the active iron sites, which results in a lower SCR performance during transient conditions. © 2014 American Institute of Chemical Engineers AIChE J, 61: 215–223, 2015 相似文献
68.
69.
Behavior of internal stakeholders in project portfolio management and its impact on success 总被引:1,自引:0,他引:1
Stakeholder behavior and stakeholder management are key success factors within project portfolio management (PPM). This empirical study of 197 project portfolios investigates the effect of the intensity of engagement (IoE) of portfolio-internal stakeholders on project portfolio success. We show that the effect of stakeholders is phase-specific and that role clarity as a measure of PPM maturity affects the nature of the relationship between the IoE of stakeholders and portfolio success. The effects of the IoE of senior managers on success are not clearly positive with regard to strategic portfolio structuring and are even negative in operative portfolio steering in established PPM systems. In immature PPM systems, line managers tend to take advantage of their position in resource management. Surprisingly, the influence of portfolio managers in portfolio steering is insignificant. Altogether, this paper shows the diverse effect of the IoE of stakeholders on portfolio success. This study enriches project research by applying stakeholder theory to the project portfolio context and offers practical guidance for further professionalizing PPM. 相似文献
70.
Engineering systems often exhibit cyclic symmetry (or rotational periodicity) of geometrical and physical properties. This paper deals with the use of this feature in the context of the direct boundary element method, and shows how to decompose an elastostatic and steady state b.v. problem with general (not cyclically symmetric) boundary conditions into a number of much smaller problems over a single segment. There is no need to discretize the interfaces between adjacent segments. The decomposition is achieved by rotational transformations of physical into cyclic components 相似文献