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931.
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933.
Douglas V. Porpora Alexander Nikolaev Julia Hagemann 《The Journal of communication》2010,60(2):254-270
W. Bennett, R. Lawrence, and S. Livingston (2006, 2007) argue that the press—and the Washington Post in particular—acquiesced to Bush administration framing of the mistreatment of prisoners at Abu Ghraib. The administration, they say, framed the events as the isolated abuse of prisoners by “a few bad apples” unreflective of higher responsibility or administration policy. Absent—or near absent, Bennett et al. maintain, was a Post counterframe of the mistreatment as a systematic effect of high level policy, better captured by the word torture. Such pattern of framing, Bennett et al. conclude, supports the Indexing model of U.S. press behavior. This article shows that Bennett et al. understate the strength and consistency of Post counterframing. When articles in the Post are searched not for individual words but for more extended frames, it becomes clear that the Post did in fact engage in considerable counterframing even in the absence of elite political opposition. This case, it is therefore concluded, does not in fact support the Indexing model as Bennett et al. maintain but is rather the kind of case described by R. M. Entman (2004) in which the press exercises greater independence of elite political opinion than the Indexing model admits. 相似文献
934.
In this work a one-dimensional mathematical model of a direct ethanol fuel cell (DEFC) is presented. The electrochemical oxidation of ethanol in the catalyst layers is described by several reaction steps leading to surface coverage with adsorbed intermediates (CH3CO, CO, CH3 and OH) and to the final products acetaldehyde, acetic acid and CO2. A bifunctional reaction mechanism is assumed for the activation of water on a binary catalyst favouring the further oxidation of adsorbates blocking active catalyst sites. The chemical reactions are highly coupled with the charge and reactant transport. The model accounts for crossover of the reactants through the membrane leading to the phenomenon of cathode and anode mixed potentials due to the parasitic oxidation and reduction of ethanol and oxygen, respectively. Polarisation curves of a DEFC were recorded for various ethanol feed concentrations and were used as reference data for the simulation. Based on one set of model parameters the characteristic of electronic and protonic potential, the relative surface coverage and the parasitic current densities in the catalyst layers were studied. 相似文献
935.
Charlotte Olagnon Dr. Julia Monjaras Feria Clemens Grünwald-Gruber Dr. Markus Blaukopf Prof. Dr. Miguel A. Valvano Prof. Dr. Paul Kosma 《Chembiochem : a European journal of chemical biology》2019,20(23):2936-2948
4-Amino-4-deoxy-l -arabinopyranose (Ara4N) residues have been linked to antibiotic resistance due to reduction of the negative charge in the lipid A and core regions of the bacterial lipopolysaccharide (LPS). To study the enzymatic transfer of Ara4N onto lipid A, which is catalysed by the ArnT transferase, we chemically synthesised a series of anomeric phosphodiester-linked lipid Ara4N derivatives containing linear aliphatic chains as well as E- and Z-configured monoterpene units. Coupling reactions were based on sugar-derived H-phosphonates, followed by oxidation and global deprotection. The enzymatic Ara4N transfer was performed in vitro with crude membranes from a deep-rough mutant from Escherichia coli as acceptor. Product formation was detected by TLC and LC-ESI-QTOF mass spectrometry. Out of seven analogues tested, only the α-neryl derivative was accepted by the Burkholderia cenocepacia ArnT protein, leading to substitution of the Kdo2-lipid A acceptor and thus affording evidence that ArnT is an inverting glycosyl transferase that requires the Z-configured double bond next to the anomeric phosphate moiety. This approach provides an easily accessible donor substrate for biochemical studies relating to modifications of bacterial LPS that modulate antibiotic resistance and immune recognition. 相似文献
936.
Kaczorowski Jessica A.; Williams Ann Shah; Smith Taylor F.; Fallah Niloofar; Mendez Julia L.; Nelson–Gray Rosemery 《Canadian Metallurgical Quarterly》2011,42(5):361
The diversity of the refugee population in the United States requires practicing psychologists to respond by adapting clinical services to meet their mental health needs. However, the available literature on culturally adapted treatments is only a first step in guiding the process for adapting clinical services. This paper describes our experiences with designing and adapting a variety of clinical services for youth and families with refugee status. Guided by Sue's (2006) tenets for culturally competent service delivery, we discuss a therapeutic model of tiered service delivery used to deliver preventative services and treatment to refugee youth and adults. We discuss how we adapted treatments to help overcome access barriers to mental health treatment, and we provide specific examples of how existing treatments were used with refugee populations. In addition, we discuss information and approaches for how practicing psychologists can develop additional skills for working with refugee populations. We conclude by focusing on the need for our field to work toward improving access to mental health treatment for refugee youth and families and developing evidence-based treatments for this population. (PsycINFO Database Record (c) 2011 APA, all rights reserved) 相似文献
937.
Work on thematic thinking, an individual's preference for basing decisions and cognitive processes on thematic similarity, has been developed recently. These preferences also build the basis for idea generation (thematic ideation) and evaluation processes. Research results indicate that there are inter‐individual differences in these preferences. We apply these findings from the field of cognition to the business context and theoretically develop and empirically test a set of antecedents and consequences of thematic thinking. Results indicate that experience and positive affect are positively related to thematic thinking. The consequences that were examined, adaptation and creativity, showed relations which were reverse to the ones hypothesized based on related prior literature. Counter‐intuitively, adaptation is positively related to thematic thinking, while creativity is negatively related. We discuss theoretical and managerial implications and highlight avenues for future research on thematic thinking. 相似文献
938.
939.
Jian Wang Kaspars Berzins Diana Hicks Julia Melkers Fang Xiao Diogo Pinheiro 《Scientometrics》2012,93(2):391-411
This paper proposes a method for classifying true papers of a set of focal scientists and false papers of homonymous authors in bibliometric research processes. It directly addresses the issue of identifying papers that are not associated (??false??) with a given author. The proposed method has four steps: name and affiliation filtering, similarity score construction, author screening, and boosted trees classification. In this methodological paper we calculate error rates for our technique. Therefore, we needed to ascertain the correct attribution of each paper. To do this we constructed a small dataset of 4,253 papers allegedly belonging to a random sample of 100 authors. We apply the boosted trees algorithm to classify papers of authors with total false rate no higher than 30% (i.e. 3,862 papers of 91 authors). A one-run experiment achieves a testing misclassification error 0.55%, testing recall 99.84%, and testing precision 99.60%. A 50-run experiment shows that the median of testing classification error is 0.78% and mean 0.75%. Among the 90 authors in the testing set (one author only appeared in the training set), the algorithm successfully reduces the false rate to zero for 86 authors and misclassifies just one or two papers for each of the remaining four authors. 相似文献
940.
Docosahexanoic acid (DHA) and eicosapentanoic acid (EPA) have been shown to possess anti-carcinogenic properties in mammary cancers, both in vitro and in vivo. The objective of this study was to investigate the effect of treating three different breast cancer cell lines with DHA or EPA on cellular growth, chemotherapy efficacy, and CD95 expression and localization in the cell. MDA-MB-231, MCF-7 and SKBr-3 cells were incubated with EPA or DHA with or without chemotherapy agents [doxorubicin (dox), Herceptin]. Cell growth was assessed by WST-1 assay and CD95 expression was investigated using flow cytometry, Western blotting and confocal microscopy. DHA and EPA inhibited the growth of all three breast cancer cell lines in a dose-dependent fashion (P?<?0.05). DHA, and to a lesser extent EPA, induced the movement and raft clustering of CD95 in the cell membrane (via confocal microscopy) and the surface expression (via flow cytometry) in MDA-MB-231 cells. Neither fatty acid altered the growth/metabolic activity of the non-transformed MCF-12A breast cell line. Pre-treatment with DHA, but not EPA, improved the efficacy of dox in estrogen receptor negative MDA-MB-231 cells (P?<?0.05), but not in the other two cell lines. Pre-treating cells with DHA increased CD95 surface expression (threefold) and the plasma membrane raft content of CD95 (2fold) and FADD (>4-fold) after dox treatment, compared to dox treatment alone (P?<?0.05). This study demonstrated that pre-treatment of estrogen receptor negative MDA-MB-231 cells with DHA increased the anti-cancer effects of dox and presents evidence to suggest that this may be mediated in part by CD95-induced apoptosis. 相似文献