Chelating,antioxidant and antiproliferative activity of <Emphasis Type="Italic">Vicia sativa</Emphasis> polyphenol extracts

The metal chelating activity, antioxidant properties, and the effect on cell growth of a polyphenol extract from Vicia sativa have been investigated, and compared to those of soybean. The extracts from V. sativa seeds contained three and five times more polyphenols and flavonoids than soybean, respectively. The soybean polyphenol extracts showed higher copper and iron chelating activity than those from V. sativa, although polyphenols from V. sativa were more effective in preventing β-carotene oxidation and showed higher reducing power and scavenging activity than soybean polyphenols. In addition, V. sativa polyphenols were toxic to THP-1 leukemic cells, as opposed to polyphenols extracted from soybean that did not show any antiproliferative activity at similar concentrations. In conclusion, V. sativa polyphenol extracts show promising antioxidant and antiproliferative activities that may be of interest from a functional point of view and for the revalorization of this ancient crop.     

Fatty acid composition of seed oil triglycerides inCoincya (Brassicaceae)

Oil and triglyceride contents and fatty acid composition were determined for seeds in nine taxa belonging to the genusCoincya (Brassicaceae) on the Iberian Peninsula (Spain and Portugal). The oil content ranges from 11.1 to 24.6%, triglycerides from 68.7 to 88.5%. The major fatty acids were erucic (24.6–30.5%), linolenic (17.7–27.7%), linoleic (13.9–24.6%) and oleic acid (12.3–21.8%).     

Flavonoids as stabilizers of fish oil: An alternative to synthetic antioxidants

The antioxidant activities against fish oil oxidation of six commercially available flavonoids and of five flavonoids purified from two Chilean native plants were compared to those ofdl-α-tocopherol and of two synthetic antioxidants, butylated hydroxytoluene and butylated hydroxyanisole. Among the commercial flavonoids, catechin, morin and quercetin showed a higher activity when fish oil oxidation (either spontaneous or Fe²⁺-induced) was assessed from the formation of peroxides or thiobarbituric acid-reactive substances. Among the native flavonoids, the 5,3′,4′-trihydroxy-7-methoxy flavanone (designated as Pt-2) showed the highest antioxidant activity. Mixtures of quercetin or of Pt-2 withdl-α-tocopherol produced better inhibitory effects when compared to that of each substance assayed by itself. Also, when Pt-2 and quercetin were assayed in combination (0.3 g/kg oil and 0.7 g/kg oil, respectively), a synergistic antioxidant effect was observed. Results indicate that several flavonoids could be used as natural antioxidants as a means to replace those synthetic antioxidants, the use of which has been questioned.     

Characterization of cross-linked polyampholytic gelatin hydrogels through the rubber elasticity and thermodynamic swelling theories

A new approach is proposed to characterize polyampholytic gelatin hydrogels, cross-linked covalently with glutaraldehyde. An experimental methodology involving simple mechanical extension and compression and equilibrium swelling tests is developed to estimate relevant microstructural parameters and electrokinetic properties of this type of hydrogel, for different cross-linker to gelatin mass ratios. The polyampholytic cross-linked matrices are studied here in the framework of the rubber elasticity and thermodynamic swelling theories. The main purposes of this work are the estimations of average mesh size and toughness of the swollen hydrogels, and the determination of the feasibility of polyion complexation between cross-linked gelatin chains and bioactive macromolecules to be delivered through hydrogel biodegradation.     

Rapid physicochemical characterization of innovative fucoidan/fructan powders by ATR–FTIR

Functional food has been highly demanded lately because of its benefits in counteracting diseases. Fucoidan and agave fructan are ingredients that enhance the growth of beneficial bacteria in the gut (prebiotics). This mixture has great potential to develop innovative products but it has never been explored before. Because of fucoidan is more expensive than agave fructan, the innovative proposed mixture is vulnerable to adulteration. This research was aimed to assess the accuracy of Fourier transform infrared spectroscopy with attenuated total reflectance (ATR–FTIR) coupled with chemometrics to identify and predict concentration of both polysaccharides in powder mixtures (0–100%). Absorption bands at 1240–1255 and 836–840 cm^?1 were attributed to fucoidan and a strong peak at ~ 936 cm^?1 confirmed the fructan presence. Peak areas were best fitted into linear models (\({\text{R}}_{\text{adj}}^{2}\) ≥ 0.92, RMSE ≤ 3.54%). This achievement may be useful to certificate ingredients contained in fucoidan–fructan mixtures, preventing adulteration.     

Assessing heterogeneity in meta-analysis: Q statistic or I2 index?

In meta-analysis, the usual way of assessing whether a set of single studies is homogeneous is by means of the Q test. However, the Q test only informs meta-analysts about the presence versus the absence of heterogeneity, but it does not report on the extent of such heterogeneity. Recently, the I2 index has been proposed to quantify the degree of heterogeneity in a meta-analysis. In this article, the performances of the Q test and the confidence interval around the I2 index are compared by means of a Monte Carlo simulation. The results show the utility of the I2 index as a complement to the Q test, although it has the same problems of power with a small number of studies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The use of preconditioned conjugate gradient and Newton-like methods for a two-dimensional,nonlinear, steady-state,diffusion/reaction problem

A combination of the Newton-like S-method of Bank and Rose[1] and the conjugate gradient method for nonsymmetric matrices described by Axelsson[7] with appropriate pre-conditioning is used in the numerical solution of a system of nonlinear elliptic partial differential equations. The S-method is used to linearize the equations and provides quadratic convergence. The preconditioned conjugate gradient algorithm is used to solve the system of N² linear equations in far fewer than N² iterations without destroying the sparsity of the matrix. The methods can be applied to a large class of problems. A two-dimensional, nonlinear, steady-state diffusion/reaction problem is solved to illustrate the use of the methods. The problem describes diffusion and reaction in a catalyst slab applicable to a two-phase, cross-flow reactor. Results for extreme problems are presented to demonstrate the usefulness and efficiency of the methods.     

Vegetation responses to precipitation and temperature: a spatiotemporal analysis of ecoregions in the Colorado River Basin

Predicting vegetation response to precipitation and temperature anomalies, particularly during droughts, is of great importance in semi-arid regions, because ecosystem and hydrologic processes depend on vegetation conditions. This article studies vegetation responses to precipitation and temperature in 10 ecological regions within the semi-arid Colorado River Basin (CRB). The Normalized Difference Vegetation Index (NDVI) from Global Inventory Modeling and Mapping Studies (GIMMS) database and the Standardized Precipitation Index (SPI) and temperature series from Parameter-Elevation Regressions on Independent Slope Models (PRISM) database were jointly evaluated for the period 1986–2006, using Multichannel Singular Spectrum Analysis (MSSA) to determine common oscillations and significant lags in vegetation response to seasonal and annual precipitation and temperature. Results show high correlations between lagged SPI series and standardized NDVI: from 1-month lag in the warm deserts (Sonora, Chihuahua and Mojave) to two months in the Temperate Sierras and Semi-Arid Highlands and three months in the Colorado and Arizona/New Mexico Plateaus and the Western Cordillera. Temperature anomalies are negatively correlated to NDVI in the lower CRB and positively correlated in the upper CRB. Notably, we see a basin-wide response to SPI anomalies, and consequently, the identified latitudinal and altitudinal lags between SPI and NDVI will allow an early, basin-wide assessment of lagged vegetation responses to precipitation along the CRB ecoregions.     

A traceability information model for CNC manufacturing

This paper proposes an information model for tracing CNC manufacturing operations. The objective of the model is to assure that traceability data is comprehensive and available for every CNC machined product, independent of the relationship between the subcontractor and the contractor. The prominent feature of the model is a link between CNC report data for a product instance, the CAD design and the CAM data. This link enables users to browse the traceability data and understand the relationships between the manufacturing process, the CAD design and the CAM data. The link is independent of the systems used to build the CAD and CAM data, and allows the users to be sure the manufactured product contains the required characteristics. Then if a product instance fails, this linkage will make possible to analyze the trace data and identify any exceptions or unusual conditions in the manufacturing process.