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31.
Karina J. Lagos Hilde H. Buzz Vanderlei S. Bagnato María Paulina Romero 《International journal of molecular sciences》2022,23(1)
Within phototherapy, a grand challenge in clinical cancer treatments is to develop a simple, cost-effective, and biocompatible approach to treat this disease using ultra-low doses of light. Carbon-based materials (CBM), such as graphene oxide (GO), reduced GO (r-GO), graphene quantum dots (GQDs), and carbon dots (C-DOTs), are rapidly emerging as a new class of therapeutic materials against cancer. This review summarizes the progress made in recent years regarding the applications of CBM in photodynamic (PDT) and photothermal (PTT) therapies for tumor destruction. The current understanding of the performance of modified CBM, hybrids and composites, is also addressed. This approach seeks to achieve an enhanced antitumor action by improving and modulating the properties of CBM to treat various types of cancer. Metal oxides, organic molecules, biopolymers, therapeutic drugs, among others, have been combined with CBM to treat cancer by PDT, PTT, or synergistic therapies. 相似文献
32.
Alicia Torres Beatriz Fuentes Karina E. Rodríguez Andrea Brito Laura Díaz 《Journal of the American Oil Chemists' Society》2020,97(6):651-661
The increasing importance of sustainability in energy production has led to a global commitment to the use of fuels derived from renewable biological sources, such as biodiesel produced from plant crops or biomass residues, that do not compete with human food for their production. For a biofuel to be considered biodiesel, it must satisfy the specifications described in the UNE 14214, with the UNE-EN 14103 referring to the determination of fatty acid methyl ester content. This standard applies gas chromatography as an analytical technique. Gas chromatography is a widely used technique in the analysis of methyl ester although it has a number of drawbacks such as: long analysis times, a high consumption of high-quality gases and internal standards, does not allow the analysis of different compounds with the same column, etc. From an industrial production point of view, is necessary to know the fatty acid methyl ester content in biodiesel samples quickly. This paper studies the development of an analytical method using Fourier transform infrared spectroscopy (FTIR) as alternative to gas chromatography (GC), since it is a simple, rapid, and precise analytical technique to quantify fatty acid methyl ester content in biofuel samples. 相似文献
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Nina Hammer Karina Mathisen Tina Zscherpe De Chen Magnus R?nning 《Topics in Catalysis》2011,54(13-15):922-930
The impact of thermal treatment at various preparation stages of carbon supported Au/TiO2 catalysts prior to oxidation of CO in the presence and absence of hydrogen was studied. An increase in catalytic activity for thermally treated samples due to a more ordered structure of TiO2 was observed. A reversible deactivation of the catalysts occurred in the absence of hydrogen. However, the activity was restored at preferential CO oxidation conditions in presence of hydrogen. 相似文献
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Karina Van Herck 《The Journal of Architecture》2013,18(3):297-301
The essay presents an alternative idea of what Islamic architecture could be from what is termed as a ‘value-centred’ approach. To date, the theory of Islamic architecture has been mainly derived either from a formalistic analysis of historically selected buildings from the past, or from the works of Sufism which claim to be the form generator of the Islamic spirit. There are also the works of regionalist architects that maintain the idea of Islamic architecture as being a product of cultural and environmental as well as geographical forces. The essay instead presents the argument that since modernist architecture was the product of a value-centred discourse ranging across political, religious and environmental issues, then Islamic architecture could also be derived from an examination of the values inherent in the hadith or traditions of the Prophet Muhammad. The body of hadiths contains many accounts of the Prophet's values concerning life practices of which some can be used in order to derive a framework of architectural design. With this framework, a re-evaluation of past historical works can be carried out and new building designs can be made from the interpretation of hadiths within the context of the cultural, geographical, economic and political settings of each project. 相似文献
38.
Bernaerts K Servaes RD Kooyman S Versyck KJ Van Impe JF 《International journal of food microbiology》2002,73(2-3):145-157
As part of the model building process, parameter estimation is of great importance in view of accurate prediction making. Confidence limits on the predicted model output are largely determined by the parameter estimation accuracy that is reflected by its parameter estimation covariance matrix. In view of the accurate estimation of the Square Root model parameters, Bernaerts et al. have successfully applied the techniques of optimal experiment design for parameter estimation [Int. J. Food Microbiol. 54 (1-2) (2000) 27]. Simulation-based results have proved that dynamic (i.e., time-varying) temperature conditions characterised by a large abrupt temperature increase yield highly informative cell density data enabling precise estimation of the Square Root model parameters. In this study, it is shown by bioreactor experiments with detailed and precise sampling that extreme temperature shifts disturb the exponential growth of Escherichia coli K12. A too large shift results in an intermediate lag phase. Because common growth models lack the ability to model this intermediate lag phase, temperature conditions should be designed such that exponential growth persist even though the temperature may be changing. The current publication presents (i) the design of an optimal temperature input guaranteeing model validity yet yielding accurate Square Root model parameters, and (ii) the experimental implementation of the optimal input in a computer-controlled bioreactor. Starting values for the experiment design are generated by a traditional two-step procedure based on static experiments. Opposed to the single step temperature profile, the novel temperature input comprises a sequence of smaller temperature increments. The structural development of the temperature input is extensively explained. High quality data of E. coli K12 under optimally varying temperature conditions realised in a computer-controlled bioreactor yield accurate estimates for the Square Root model parameters. The latter is illustrated by means of the individual confidence intervals and the joint confidence region. 相似文献
39.
A survey was conducted in a sample of 894 students entering a private university in S?o Paulo to examine the vitamin beliefs and to verify the relation between vitamin beliefs and vitamin supplements consumption. Nineteen statements about the relation between vitamins and health were developed to assess the beliefs; the respondents answered by means of a 5-point agreement scale. Cronbach's alpha coefficient of internal consistency was determined for the total scale. 94.5% of students believe that vitamin C prevents and cures the common cold and 72.5% consider vitamins as an energy source. Many students recognize the possibility of health risks associated to excessive vitamin consumption. Vitamin supplement users had a belief score higher than non-users (p < 0.001). The results indicate that several misconceptions about vitamin benefits are common among the students and suggest a relation between vitamin beliefs and supplements consumption. 相似文献
40.
Ma R Golberg D Bando Y Sasaki T 《Philosophical transactions. Series A, Mathematical, physical, and engineering sciences》2004,362(1823):2161-2186
The current status of research on boron-carbon-nitrogen (B-C-N) and boron nitride (BN) nanotubes is presented. The latest achievements in syntheses, analyses and property measurements of these nanoscale tubular architectures are reviewed. The characteristic features of B-C-N and BN nanotubes, compared with conventional C nanotubes, are paid special attention. In particular, the latest breakthroughs in the chemical vapour deposition synthesis of BN nanotubes and an insight into their unique structures are highlighted. A wide range of potential applications is also envisaged, based on the recent progress, which includes pioneering results in BN nanocable fabrication, gas adsorption, electron transport and field emission measurements. 相似文献