Image retrieval based on histogram of fractal parameters

Image indexing and retrieval techniques are important for efficient management of visual databases. These techniques are generally developed based on the associated compression techniques. In the fractal domain, luminance offset and contrast scaling parameter are typically used as the fractal indices. However, luminance offset and contrast scaling parameter are strongly correlated. In this paper, we prove that range block mean and contrast scaling parameters are independent. Based on this independence, we propose four statistical indices for efficient image retrieval. In addition, we propose an efficient hierarchical indexing strategy based on the de and ac component analysis. Experimental results on a database of 416 texture images, created by decomposing 26 images, indicate that the proposed indices significantly improve the retrieval rate, compared to other retrieval methods.     

A spatially curved‐beam element with warping and Wagner effects

This paper presents a new spatially curved‐beam element with warping and Wagner effects that can be used for the non‐linear large displacement analysis of members that are curved in space. The non‐linear behaviour of members curved in space shows that the Wagner effects are substantial in the large twist rotation analysis. Most existing finite beam element models, such as ABAQUS and ANSYS cannot predict the non‐linear large displacement response of members curved in space correctly because the Wagner effects, viz. the Wagner moment and the corresponding finite strain terms, have not been considered in these finite beam elements. As a consequence, these finite beam elements do not provide correct predictions for the out‐of‐plane buckling and postbuckling behaviour of arches as well. In this paper, the symmetric tangent stiffness matrix has been derived based on the finite rotations parameterized by the conventional displacements. The warping and Wagner effects: both the Wagner moment and the corresponding finite strain terms and their constitutive relationship, are included in the spatially curved‐beam element. Two components of the initial curvature, the initial twist and their interactions with the displacements are also considered in the spatially curved‐beam element. This ensures that the large twist rotation analysis for the members curved in space is accurate. Comparisons with existing experimental, analytical and numerical results show that the spatially curved‐beam element is accurate and efficient for the non‐linear elastic analysis of curved members, buckling and postbuckling analysis of arches, and in its ability to predict large deflections and twist rotations in more arbitrarily curved members. Copyright © 2005 John Wiley & Sons, Ltd.     

通信网需要优质的电力供给

近十年来,通信行业一直是我国发展最迅猛、技术更新最快的行业之一。随着基础技术和系统技术的发展,通信网本身正走向更高的层次,相应的对通信电源的性能、可靠性要求也不断提高。为此,1996年1月原邮电部发布了《通信局(站)电源系统总技术要求》(暂行规定)及(1996)105号文件,明确指出通信局(站)电源系统应实现集中监控,逐步实现少人或无人值守,把集中监控列为通信电源系统的一个必不可少的部分。这里所指的集中监控系统是利用先进的信息技术、控制技术及计算机应用技术成果,对分布在不同通信局(站)的电源、油机、蓄电池、UPS、逆变器、高…     

Thermodynamic Studies of Interactions between Sertraline Hydrochloride and Randomly Methylated β-Cyclodextrin Molecules Supported by Circular Dichroism Spectroscopy and Molecular Docking Results

The interaction between sertraline hydrochloride (SRT) and randomly methylated β-cyclodextrin (RMβCD) molecules have been investigated at 298.15 K under atmospheric pressure. The method used—Isothermal Titration Calorimetry (ITC) enabled to determine values of the thermodynamic functions like the enthalpy (ΔH), the entropy (ΔS) and the Gibbs free energy (ΔG) of binding for the examined system. Moreover, the stoichiometry coefficient of binding (n) and binding/association constant (K) value have been calculated from the experimental results. The obtained outcome was compared with the data from the literature for other non-ionic βCD derivatives interacting with SRT and the enthalpy-entropy compensation were observed and interpreted. Furthermore, the connection of RMβCD with SRT was characterized by circular dichroism spectroscopy (CD) and complexes of βCD derivatives with SRT were characterized through the computational studies with the use of molecular docking (MD).     

Dehydrogenation of Betacyanins in Heated Betalain-Rich Extracts of Red Beet (Beta vulgaris L.)

Betacyanins are a group of water-soluble red-violet compounds containing nitrogen in their structure. These are biosynthesized in red beetroot (Beta vulgaris L.), a widely consumed vegetable that contains significant amounts of nutritious and bioactive compounds which are also found in dietary supplements. This contribution presents results of betacyanin thermal oxidation (resulting in dehydrogenation) interrelated with decarboxylation in selected acetate/phosphate buffers at pH 3–8 and at 85 °C, which may be of particular significance for formulation and performance of foods. Most of the reaction products were detected at the highest concentrations in the acidic solutions (pH 3–4). The main dehydrogenation reaction pathways were monitored by LC-DAD-MS/MS and were associated with decarboxylation of the principal extract pigments, betanin/isobetanin and neobetanin, at carbon positions C-2 and C-17. Additional reactions are accompanied by the 2,15-decarboxylation processes at different dehydrogenation levels with 15-decarboxy-betanin and 2,15-bidecarboxy-betanin, structurally elucidated by NMR analysis, as the distinct indicators of this route type. For other novel pigments detected, 2,15-bidecarboxy-xanbetanin, 2,15-bidecarboxy-xanneobetanin and 2,15,17-tridecarboxy-neobetanin, additional high resolution mass spectrometric analyses were performed and confirmed their molecular formulas.     

Colon Expression of Chemokines and Their Receptors Depending on the Stage of Colitis and Oat Beta-Glucan Dietary Intervention—Crohn’s Disease Model Study

Crohn’s disease (CD), a condition characterized by chronic inflammation of the gastrointestinal tract with alternating periods of exacerbation and remission, is becoming common around the world. This study aimed to analyze the molecular mechanisms underlying the anti-inflammatory properties of oat beta-glucans of varying molar masses by modulating the expression of chemokines and their receptors as well as other proteins related to both stages of TNBS (2,4,6-trinitrobenzosulfonic acid)-induced colitis, which is an animal model of CD. The experiment involved 96 Sprague–Dawley rats, which were divided into two main groups: control and TNBS-induced colitis. Both groups of rats were further divided into three dietary subgroups, which were fed with standard feed or feed supplemented with low- or high-molar-mass oat beta-glucans for 3 (reflecting acute inflammation) or 7 days (reflecting pre-remission). The gene expression of chemokines and their receptors in the colon wall was determined by RT-PCR, and the expression of selected proteins in the mucosa was determined by immunohistochemical analysis. The results showed that acute and pre-remission stages of colitis were characterized by the increased gene expression of seven chemokines and four chemokine receptors in the colon wall as well as disrupted protein expression of CXCL1, CCL5, CXCR2, CCR5, and OPN in the mucosa. The consumption of oat beta-glucans resulted in decreased expression of most of these genes and modulated the expression of all proteins, with a stronger effect observed with the use of high-molar-mass beta-glucan. To summarize, dietary oat beta-glucans, particularly those of high molar mass, can reduce colitis by modulating the expression of chemokines and their receptors and certain proteins associated with CD.     

Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer

Colorectal cancer (CRC) is the third most frequently diagnosed malignancy worldwide. Only 5% of all CRC cases are due to germline mutations in known predisposition genes, and the remaining genetic burden still has to be discovered. In this study, we performed whole-exome sequencing on six members of a Polish family diagnosed with CRC and identified a novel germline variant in the protein tyrosine kinase 7 (inactive) gene (PTK7, ENST00000230419, V354M). Targeted screening of the variant in 1705 familial CRC cases and 1674 healthy elderly individuals identified the variant in an additional familial CRC case. Introduction of this variant in HT-29 cells resulted in increased cell proliferation, migration, and invasion; it also caused down-regulation of CREB, p21 and p53 mRNA and protein levels, and increased AKT phosphorylation. These changes indicated inhibition of apoptosis pathways and activation of AKT signaling. Our study confirmed the oncogenic function of PTK7 and supported its role in genetic predisposition of familial CRC.     

Composites Based on Gellan Gum,Alginate and Nisin-Enriched Lipid Nanoparticles for the Treatment of Infected Wounds

Due to growing antimicrobial resistance to antibiotics, novel methods of treatment of infected wounds are being searched for. The aim of this research was to develop a composite wound dressing based on natural polysaccharides, i.e., gellan gum (GG) and a mixture of GG and alginate (GG/Alg), containing lipid nanoparticles loaded with antibacterial peptide—nisin (NSN). NSN-loaded stearic acid-based nanoparticles (NP_NSN) were spherical with an average particle size of around 300 nm and were cytocompatible with L929 fibroblasts for up to 500 µg/mL. GG and GG/Alg sponges containing either free NSN (GG + NSN and GG/Alg + NSN) or NP_NSN (GG + NP_NSN and GG/Alg + NP_NSN) were highly porous with a high swelling capacity (swelling ratio above 2000%). Encapsulation of NSN within lipid nanoparticles significantly slowed down NSN release from GG-based samples for up to 24 h (as compared to GG + NSN). The most effective antimicrobial activity against Gram-positive Streptococcus pyogenes was observed for GG + NP_NSN, while in GG/Alg it was decreased by interactions between NSN and Alg, leading to NSN retention within the hydrogel matrix. All materials, except GG/Alg + NP_NSN, were cytocompatible with L929 fibroblasts and did not cause an observable delay in wound healing. We believe that the developed materials are promising for wound healing application and the treatment of bacterial infections in wounds.     

自控数-模式节流控制及应用的研究

从数模的转换角度出发,把数模转换引入液压控制中,通过数元（即节流孔）对节流控制口大小实行数－模转换控制,从而探求一种更简单、更精确的控制形式。     

Synthesis and luminescence of Eu3+ doped nanocrystalline TiO2 spheres

Eu~(3+) doped TiO_2 anatase spheres were obtained by modified sol-gel approach.Spheres(110—250 nm) are composed of smaller(5-15 nm) nanocrystals and exhibit red emission under UV light excitation.Materials were synthesized by multi-step method from glycolated titania alkoxides.Europium doped(1.0 mol%) and non-doped spheres were synthesized.Their optical and structural properties were compared by materials characterization methods,such as X-ray powder diffraction,transmission electron microscopy and PL spectroscopy.Doped TiO_2 spheres are crystalline phase pure and exhibit high luminescence intensity.