A case report of angiomyolipoma arising from the renal capsule

A case of angiomyolipoma arising from the renal capsule is reported. A 49-year-old female was admitted to our hospital with a complaint of abdominal mass pointed out by ultrasonography during her yearly health check. The tumor was 10 cm in size. On abdominal enhanced CT, the tumor was existed behind the left kidney. The capsule of the tumor was enhanced and the septums were seen inside of the tumor. MRI revealed a hemorrhage in the tumor and selective renal angiography showed the tumor was fed by the renal capsular artery. A tumor of the renal capsule was suspected and a laparotomy was done. Pathological results by the frozen section suggested malignancy and radical nephrectomy was performed. Angiomyolipoma was diagnosed histologically. Tumors of the renal capsule are uncommon and angiomyolipoma of the renal capsule is extremely rare. We have found only two cases in Japanese medical literature.     

High peak power and high repetition rate characteristics in acurrent-pulsed Q-switched CO2 laser with a mechanical shutter

An electro-mechanical Q-switched (EMQ) CO₂ laser is Q-switched by a mechanical beam chopper in combination with a pulsed discharge current. Such a system can produce pulses with high peak powers (>10 kW) and high repetition rates (>1 kpps). In order to analyze the output characteristics, the peak power and the duration of the output pulses have been measured experimentally in detail over a wide range of Q-switching times up to 250 ns. For a low-pressure (<4 kPa) CO₂ gas system, the standard rate equations adequately explain the experimental results by introducing a new switching function for the form of the cavity loss for the mechanical chopper. In an EMQ-laser with a high initial inversion density (4.5·10¹⁵ /cm³ at 150 mA peak current), multiple peak pulses or pulse distortion have been observed. This is due to the plasma screening effect induced by the burning of the metal shutter blades placed inside the cavity. It is found that tungsten metal shutter blades can be used up to a power density of 259 MW/cm² for a focused beam without this effect occurring, The solutions of the rate equations show that optimum coupling can prevent the plasma screening effect even for a Q-switching time longer than the pulse buildup time. The EMQ-laser configured for optimum coupling has produced a peak output power of 30 kW for the 9P20 transition branch in the CO₂ spectrum without any pulse distortion. This value has been obtained even though the discharge length was only 1.3 meters     

Studies on social learning in Japan.

An increasing concern in contemporary psychology in Japan is the study of observational learning and imitation in the social learning, personality, and clinical fields. The literature in these fields from 1964 to 1975 is reviewed, including learning-by-observing vs learning-by-performing, observer learning, the process of observational learning, mediational processes, effects of motivation on observational learning, effects of various reinforcement factors underlying modeling, the relationship between model and observer, observational learning studies unique to Japan, application of modeling to clinical fields, and self-reinforcement. (1? p ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Solubility and susceptibility of carbonaceous quinoline-insoluble substances including mesophase material in the co-carbonization process

The solubility and susceptibility of carbonaceous quinoline-insoluble substances (QI) including mesophase material were studied in co-carbonizations with pitch-based materials by evaluating the homogeneity and the size of the anisotropic optical texture in resultant cokes. The efficacy of co-carbonization is attributed to the nature of both the Ql substance and pitch-based materials. The order of the modifying ability of the partner is CP-BSfa values and Rnus (number of naphthenic rings per structural unit)/Rtus (number of total rings per structural unit). The hydrogen donating ability of the pitch material may be the most important property able to modify the non-fusible QI. The order of ability to be modified of the QI substances (susceptibilty) is KPQI-EtBS>soft mesophase>hard mesophase>KPQI. These abilities appear to be related to their fusibility and dependent upon their chemical structure defined by their origin and heat-treatment history. The molecular weight (extent of condensation) and the hydrogen content (favourably naphthenic hydrogen) of the components may be the most important factors. This approval is relevant to the preparation of suitable carbon fiber precursors from Ql material including mesophase.     

Time course of ethylene thiourea in maternal plasma, amniotic fluid and embryos in rats following single oral dosing

Ethylene thiourea (ETU) was administered once orally to pregnant rats on gestation day 12 at a dose of 200 mg/kg, and its concentration-time courses in the maternal plasma, amniotic fluid and embryos were investigated. The ETU concentrations in the maternal plasma and amniotic fluid reached the peak level about 2 hr after dosing, then declined gradually and had disappeared by 48 hr. In embryos, the concentration of ETU peaked at 30 min after dosing and disappeared at 48 hr. The prolonged exposure of the embryos to the high concentration of ETU in the amniotic fluid could be partially responsible for the teratogenic effect of ETU.     

Clinical analysis of elderly patients with malignant lymphoma

An epidemiological study on 173 consecutive elderly malignant lymphoma patients age 65 years or over was performed and the clinical outcome of chemotherapy is reported. Of there, 131 patients (75.7%) had non-Hodgkin's lymphoma (NHL) and 21 patients had Hodgkin's disease (HD). As for clinical staging, 58.9% of patients were in stage 3 or 4. The initial sites were nodal in 61.8% of the patients the most common sites of involvement in superficial lymph nodes being cervical, inguinal and axillar. The most frequent site of extranodal involvement was the gastrointestinal tract. The cases were treated with CHOP/COPP, BACOP or COP-BLAM combination chemotherapy. The clinical efficacy of these modalities was similar, with complete remission rates being about 50%. However, the total response rate (CR+partial remission) by the COP-BLAM regimen were 88.1%. The median survival time of cases achieving CR, was longer than 47 months. The most frequent cause of death was infection, especially pneumonia and septicemia. Many elderly ML patients were found and diagnosed when the disease developed to an advanced stage. Therefore it is necessary to make efforts to find early ML patients by screening apparently healthy elderly people. Improvement of the complete remission rate should be obtained if vigorous and intensive chemotherapy is carried out with careful supportive therapy concerning the general condition and complications in patients.     

Production of a yogurt-like product from plant foodstuffs and whey. Substrate preparation and fermentation

A mixed substrate composed of soya milk, oat flour and dried cheese whey (82, 11 and 7% respectively) had a content of lactose and protein similar to that of milk used for yogurt manufacture. Heat treatment for 20 min at 80°C resulted in a viscosity similar to that of yogurt whilst removing coliform and mesophilic aerobic bacteria, moulds and yeasts. Fermentation with traditional yogurt bacteria did not increase viscosity further, and the final product had similar acidity and texture to yogurt. Acid development, carbohydrate consumption, proteolysis and starters counts were followed during fermentation. The fermentation profile of the mixed substrate was very similar to that of milk.     

Effect of nonenzymatic glycosylation on the titers of circulating autoantibodies in pemphigus and pemphigoid

Hyperglycemia is observed in some patients with autoimmune bullous diseases complicated by diabetes mellitus or treated with systemic corticosteroids. High concentrations of glucose can react with various proteins and change their structural and functional properties. We previously reported that nonenzymatic glycosylation of antibody can impair antigen-antibody binding. We ascertained whether glycosylation of autoantibody decreases the autoantibody titer by examining 30 sera from patients with pemphigus and pemphigoid. Nonenzymatic glycosylation in the physiological range was induced by incubation of sera with 1650 mM D-glucose at 4 degrees C for 7 days. The titers of sera were determined by indirect immunofluorescence (IIF). In all cases, the immunofluorescence intensity of glycosylated sera was weaker than that of nonglycosylated sera. Glycosylated sera showed a lower antibody titer by 1 doubling dilution in 18 out of 30 cases, compared with nonglycosylated sera. The ten BP patients' sera were also analyzed by immunoblotting for reactivity with the BP180-GST fusion proteins, S delta 1 and 4575. All BP sera reacted with S delta 1, and 5 out of 10 BP sera reacted with both S delta 1 and 4575. In all the sera that reacted only with S delta 1, the glycosylated sera showed a 1 doubling dilution decrease in autoantibody titer. Interestingly, in 4 out of 5 sera that reacted with both S delta 1 and 4575, there were no differences in the antibody titer between glycosylated and nonglycosylated sera. These results indicate the possibility of a false decrease in autoantibody titers of sera from patients with autoimmune bullous diseases complicated with hyperglycemia. Although the false decrease in titers of autoantibodies induced by nonenzymatic glycosylation is not dramatic, it must be considered in order not to underestimate the disease activity of pemphigus in such cases.     

Three-dimensional spiral computed tomography angiography as an alternative imaging modality for a silent dissecting aortic aneurysm--a case report

The authors report a patient with silent dissecting aortic aneurysm in whom three-dimensional spiral computed tomography (CT) angiography (3D-CTA) provided important imaging data. Images obtained by 3D-CTA were compared with the results of both conventional angiography and CT. They conclude that 3D-CTA was a powerful diagnostic modality for this patient, in addition to conventional CT and angiography.