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91.
In this paper, we sketch some of the challenges that should be addressed in future research efforts for model-based decision support in manufacturing and service networks. This includes integration issues, taking into account the autonomy of the decision-making entities in face of information asymmetry, the modeling of preferences of the decision-makers, efficiently determining robust solutions, i.e. solutions that are insensitive with respect to changes in the problem data, and a reduction of the time needed for model building and usage. The problem solution cycle includes problem analysis, the design of appropriate algorithms and their performance assessment. We are interested in a prototypical integration of the proposed methods within application systems, which can be followed up with field tests of the extended application systems. We argue that the described research agenda requires the interdisciplinary collaboration of business and information systems engineering researchers with colleagues from management science, computer science, and operations research. In addition, we present some exemplifying, illustrative examples of relevant research results.  相似文献   
92.
An integral equation method for solving the eddy-current nondestructive evaluation problem of a flat, rectangular, near surface crack inside of a cylindrical hole in a conducting material is presented. The method involves expanding the Green’s tensor, the incoming field, and the jump in electric potential over the crack in suitable basis functions. Here, plane waves, cylindrical waves, and basis functions related to the Chebyshev polynomials, are used. The way of discretization in this method leads to a formulation where the scattering is defined by a scattering matrix, independent of the incoming field. This presents an advantage, when conducting numerical simulations, since the scattering matrix does not have to be recalculated for every probe position. The numerical calculations are straightforward to perform and model predictions are compared with finite element results.  相似文献   
93.
Mammalian cells are the preferred host for the manufacture of a wide range of biopharmaceuticals, but production costs are high owing to low productivity. A range of rational engineering strategies have been pursued in order to increase volumetric product titres from mammalian cells, such as delaying apoptosis, manipulation of the cell cycle, and improving metabolism and protein processing. Unfortunately, outcomes from these strategies have been mixed, with few instances where significant improvements in product yield have been achieved. This article reviews and contrasts many of the engineering strategies attempted to date, highlighting the variability and context specificity in outcome. The paper argues that this is a reflection of the complexity of mammalian cells, and that a deeper understanding of the biology underpinning protein production for biotechnological purposes is required. Copyright © 2011 Society of Chemical Industry  相似文献   
94.
Flow measurements often take place under difficult conditions. Optical flow measurement techniques are affected by variations of the refractive index, caused e.g., by temperature, concentration, or pressure gradients. This will give rise to an increased measurement uncertainty or cause the measurement to fail. To overcome these limitations, we propose the employment of adaptive optics. In this contribution we present interferometric flow velocity measurements through a fluctuating air-water interface by the use of adaptive optics. Using the adaptive optics, the rate of valid measurement signals can be improved from 28% to 83%. The results are promising to enable measurements in difficult environments affected by refractive index variations which were not accessible so far.  相似文献   
95.
Thermobaric stratification was investigated in very deep lakes of elongated shape. We considered the spring time configuration when large freshwater lakes may have their deepest recirculation. In five very deep freshwater lakes in Norway, profiles were measured in spring 2006 with multiparameter probes. Temperature profiles confirmed thermobaric stratification in all of these lakes, i.e. the temperature profiles crossed the 4 °C line and thus were affected by pressure effects on the temperature of maximum density. Electrical conductance was low in all of the investigated lakes, and vertical gradients were too small to play a role in the density stratification. In all lakes, deep water was well supplied with oxygen. Three out of five lakes showed a temperature gradient close to Eklund's stability theorem. However, the remaining two lakes clearly opposed the theorem. Bottom temperatures were more closely related to lake length than their maximum depths. Oxygen saturation profiles documented recent intensive gas exchange with the atmosphere. They agree well with the possible formation of deep water from density driven flows at horizontal temperature gradients close to 4 °C.  相似文献   
96.
As a service to readers, Wind Energy regularly conducts literature surveys and publishes lists of relevant articles drawn from recent issues of a large number of periodicals including the following: Journal of Wind Engineering and Industrial Aerodynamics, International Journal of Energy Research, Renewable Energy, Energy Sources, Journal of Solar Energy Engineering, American Institute of Aeronautics and Astronautics Journal and Electric Power Components and Systems along with a number of periodicals published by the Institute of Electrical and Electronics Engineers, etc. The list is limited exclusively to journals not specifically devoted to wind energy and its applications. To assist the reader, the list is separated into broad categories. Although many papers fit several categories, each paper is listed only once under the category thought most appropriate. Please note that the inclusion in the list is not an endorsement of a paper's quality. Please e‐mail any suggestions to corresponding author. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献   
97.
The resulting surface quality after 5-axis ball end milling is of superior importance because finish milling is often the last process step determining the functional performance of a component. However, the prediction of surface topography is still a challenging task. Especially in ball end milling with the characteristic sickle shaped chip cross section, ploughing effects in the area of low chip thickness result in plastic deformation and surface defects (also known as burr). This paper provides a new approach to predict those surface defects by considering the minimum chip thickness for complex milling engagement conditions within a virtual process design. This allows the choice of suitable process parameters without extensive experimental efforts.  相似文献   
98.
In many technical processes gas, multicomponent diffusion takes place in confinements that are rarely uniform in direction of their long axis (e.g., catalysts pores). Here, we show that in conical tubes multicomponent diffusion is hindered. This effect increases with ratio of inlet to outlet cone radius Λ, indifferent of the orientation of the tube. Based on the Maxwell–Stefan equations, predictive analytical solution for ideal multicomponent diffusion in slightly tapered ducts is developed. In two‐bulb diffusion experiments on a uniform tube, the results of Duncan and Toor (1962) were reproduced. Comparison of model and experiment shows that the solution presented here provides a reliable quantitative prediction of the temporal change of H2, N2, and CO2‐concentration for both tube geometries, uniform and slightly conical. In the demonstrated case (Λ = 3.16), mass diffusion is 68% delayed. Thus, for gaseous diffusion in “real,” typically tapered pores the transport limitation is more serious than considered so far. © 2014 American Institute of Chemical Engineers AIChE J, 61: 1404–1412, 2015  相似文献   
99.
The use of bio‐based nanoscaled cellulose for the construction of novel functional materials has progressed rapidly over the past years. In comparison to most of studies starting with the hydrophilic nanoscaled cellulose, surface‐stearoylated cellulose nanoparticles (SS‐CNPs) are used in this report for the construction of multifunctional, responsive films. SS‐CNPs with an average size of 115 ± 0.5 nm are obtained after the surface‐modification of cellulose under heterogeneous conditions. Crystalline cellulose core is present within SS‐CNPs according to solid‐state 13C nuclear magnetic resonance (NMR) spectroscopy. SS‐CNPs show excellent dispersibility in nonpolar solvents and form temperature‐responsive organogels in tetrahydrofuran (THF) at low temperature or after long time storage at room temperature. Moreover, transparent and self‐standing films of SS‐CNPs from their THF‐suspension show solvent‐responsive surface wettability and responsive shape‐memory property. SS‐CNPs can also be used for the fabrication of nanocomposite films together with nonpolar compounds, such as (2‐stearoylaminoethyl) rhodamine B. Thus, these novel SS‐CNPs derived from sustainable cellulose fibers are promising candidates for the construction of novel functional materials.  相似文献   
100.
Herein, we report—for the first time—on the additive‐free bulk synthesis of Ti3SnC2. A detailed experimental study of the structure of the latter together with a secondary phase, Ti2SnC, is presented through the use of X‐ray diffraction (XRD), and high‐resolution transmission microscopy (HRTEM). A previous sample of Ti3SnC2, made using Fe as an additive and Ti2SnC as a secondary phase, was studied by high‐temperature neutron diffraction (HTND) and XRD. The room‐temperature crystallographic parameters of the two MAX phases in the two samples are quite similar. Based on Rietveld analysis of the HTND data, the average linear thermal expansion coefficients of Ti3SnC2 in the a and c directions were found to be 8.5 (2)·10?6 K?1 and 8.9 (1)·10?6 K?1, respectively. The respective values for the Ti2SnC phase are 10.1 (3)·10?6 K?1 and 10.8 (6)·10?6 K?1. Unlike other MAX phases, the atomic displacement parameters of the Sn atoms in Ti3SnC2 are comparable to those of the Ti and C atoms. When the predictions of the atomic displacement parameters obtained from density functional theory are compared to the experimental results, good quantitative agreement is found for the Sn atoms. In the case of the Ti and C atoms, the agreement is more qualitative. We also used first principles to calculate the elastic properties of both Ti2SnC and Ti3SnC2 and their Raman active modes. The latter are compared to experiment and the agreement was found to be good.  相似文献   
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