An overall model for maintenance optimization

This paper presents an approach for identifying the optimal maintenance schedule for the components of a production system. Safety, health and environment objectives, maintenance costs and costs of lost production are all taken into consideration, and maintenance is thus optimized with respect to multiple objectives. Such a global approach to maintenance optimization requires expertise from various fields, e.g., decision theory, risk analysis and reliability and maintenance modelling. Further, a close co-operation between management, maintenance personnel and analysts is required to achieve a successful result. In the past this has been a major obstacle to the extensive use of proper maintenance optimization methods in practice, and techniques to promote the communication between the involved parties of the optimization process is an essential element in the suggested approach. A simple step by step presentation of the required modelling is provided. Contrary to most current methods of RCM (Reliability Centered Maintenance), the approach is based on an analytic model, and therefore gives a sound framework for carrying out a proper maintenance optimization. The approach is also flexible as it can be carried out at various levels of detail, e.g., adopted to available resources and to the managements willingness to give detailed priorities with respect to objectives on safety vs production loss.     

Design and Characterization of the CLIMPAQ,Chamber for Laboratory Investigations of Materials,Pollution and Air Quality*

A test chamber has been developed in order to provide a small and simple emission testing facility capable of testing construction products in a climate where the important climatic parameters such as temperature, ventilation rate and air velocity can be varied independently around typical indoor values. The test chamber CLIMPAQ is made of panes of window glass. Other main surface materials are stainless steel and eloxated aluminium. The chamber has a volume of 50.9 litres and is designed to meet the requirements for quantifying air pollution. In this investigation human subjects acted as air pollution judges, and chemical characterization of the air pollution was carried out. Carpet, linoleum, wall paint and seal- ant were tested simultaneously in the CLIMPAQ and in four other chambers ranging from a full-scale chamber of 28 m³ to a field and laboratory emission cell of 3.5· 10^?5m³. Product ranking is the same in all chambers for the sensory measurements. Emission rates based on sensory measurements differ for all products less than 100 % except for tests in a 3-litre chamber where emission rates were higher. Chemical measurements differ up to approximately 10 times for the same product in different chambers. Deviations appear to be the result of different environmental parameters in the various chambers. Low air concentrations or high specific ventilation rates seem to increase emissions, while differences in air velocities and sink properties may also be the cause of differences in emission rates.     

Evidence for Remote Effects of Dreissenid Mussels on the Amphipod Diporeia: Analysis of Lake Ontario Benthic Surveys, 1972–2003

The status of invasive dreissenid mussels (Dreissena polymorpha and D. bugensis) and native amphipods (Diporeia spp.) in Lake Ontario was assessed in 2003 and compared with historical data. D. polymorpha (zebra mussels) were rarely observed in 2003, having been displaced by D. bugensis (quagga mussels). D. bugensis expanded its depth range from 38 m depth in 1995 to 174 m in 2003 and this dreissenid reached densities averaging 8,000/m² at all sites < 90 m. During the same time period, Diporeia populations almost completely disappeared from 0–90 m depth, continuing a declining trend from 1994–1997 reported in previous studies. The average density of Diporeia in the 30–90 m depth interval decreased from 1,380/m² to 63/m² between 1997 and 2003. Prior to 2003, areas deeper than 90 m represented a refuge for Diporeia, but even these deep populations decreased, with densities declining from 2,181/m2 in 1999 to 545/m2 in 2003. Two common hypotheses for the decline of Diporeia in the Great Lakes are food limitation and a toxin/pathogen associated with dreissenid pseudofeces. The Diporeia decline in deep waters preceded the expansion of D. bugensis to these depths, and suggests that shallow dreissenid populations remotely influence profundal habitats. This pattern of decline is consistent with mechanisms that act from some distance including nearshore dreissenid grazing and downslope transport of pseudofeces.     

External-Memory Algorithms for Processing Line Segments in Geographic Information Systems

In the design of algorithms for large-scale applications it is essential to consider the problem of minimizing I/O communication. Geographical information systems (GIS) are good examples of such large-scale applications as they frequently handle huge amounts of spatial data. In this paper we develop efficient external-memory algorithms for a number of important problems involving line segments in the plane, including trapezoid decomposition, batched planar point location, triangulation, red--blue line segment intersection reporting, and general line segment intersection reporting. In GIS systems the first three problems are useful for rendering and modeling, and the latter two are frequently used for overlaying maps and extracting information from them.     

Integration of multiple national markets for electricity: The case of Norway and Sweden

During the second part of the 1990s the Nordic (Denmark, Finland, Norway and Sweden) countries have created a unique multinational market for electricity. This paper aims to analyse the degree of integration of the different national markets that constitute the Nordic electricity market. In particular the Norwegian and Swedish wholesale and retail electricity markets are analysed. The results suggest that the wholesale markets are well integrated. Thus prices differ significantly only during periods with unusually high or low supply of hydropower. However, the retail markets are not integrated to the same degree. Thus retail prices and trade margins differ significantly. Differences in the national electricity market legislation seem to be a key factor behind these differences.     

Agile distributed software development: enacting control through media and context

While face‐to‐face interaction is fundamental in agile software development, distributed environments must rely extensively on mediated interactions. Practicing agile principles in distributed environments therefore poses particular control challenges related to balancing fixed vs. evolving quality requirements and people vs. process‐based collaboration. To investigate these challenges, we conducted an in‐depth case study of a successful agile distributed software project with participants from a Russian firm and a Danish firm. Applying Kirsch's elements of control framework, we offer an analysis of how control was enacted through the project context and in the participants' mediated communication. The analysis reveals that formal measurement and evaluation control were persistently enacted through mediated communication. These formal control practices were, however, predominantly carried out in conjunction with informal roles and relationships such as clan‐like control inherent in agile development. Overall, the study demonstrates that, if appropriately applied, communication technologies can significantly support distributed, agile practices by allowing concurrent enactment of both formal and informal controls. The paper discusses these findings as they relate to previous research and concludes with their implications for future research.     

MS Binding Assays for Glycine Transporter 2 (GlyT2) Employing Org25543 as Reporter Ligand

This study describes the first binding assay for glycine transporter 2 (GlyT2) following the concept of MS Binding Assays. The selective GlyT2 inhibitor Org25543 was employed as a reporter ligand and it was quantified with a highly sensitive and rapid LC-ESI-MS/MS method. Binding of Org25543 at GlyT2 was characterized in kinetic and saturation experiments with an off-rate of 7.07×10⁻³ s⁻¹, an on-rate of 1.01×10⁶ M⁻¹ s⁻¹, and an equilibrium dissociation constant of 7.45 nM. Furthermore, the inhibitory constants of 19 GlyT ligands were determined in competition experiments. The validity of the GlyT2 affinities determined with the binding assay was examined by a comparison with published inhibitory potencies from various functional assays. With the capability for affinity determination towards GlyT2 the developed MS Binding Assays provide the first tool for affinity profiling of potential ligands and it represents a valuable new alternative to functional assays addressing GlyT2.     

Effect of Density and Processing Conditions on Oxide Transformations and Mechanical Properties in Cr–Mo-Alloyed PM steels

To improve the mechanical properties and performances of water-atomized powder metallurgy steels, it is necessary to enhance the density. Consolidating water-atomized steel powders via conventional pressing and sintering to a relative density level > 95 pct involves processing challenges. Consolidation of gas-atomized powders to full density by hot isostatic pressing (HIP) is an established process route but utilizing water-atomized powders in HIP involves challenges that result in the formation of prior particle boundaries due to higher oxygen content. In this study, the effect of density and processing conditions on the oxide transformations and mechanical properties from conventional press and sintering, and HIP are evaluated. Hence, water-atomized Cr–Mo-alloyed powder is used and consolidated into different density levels between 6.8 and 7.3 g cm⁻³ by conventional die pressing and sintering. Fully dense material produced through HIP is evaluated not only of mechanical properties but also for microstructural and fractographic analysis. An empirical model based on power law is fitted to the sintered material properties to estimate and predict the properties up to full density at different sintering conditions. A model describing the mechanism of oxide transformation during sintering and HIP is proposed. The challenges when it comes to the HIP of water-atomized powder are addressed and the requirements for successful HIP processing are discussed.