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41.
Laura Peters 《集成电路应用》2007,(11):31-31
成品率预测是可制造性设计(DFM)的基础之,但它还远不止于此。IBM系统和技术群300mm半导体运营副总裁DanArmbrust说:“我们精确预测成品率的能力就是我们的经济模式。”Armbrust是SEMICON West 2007成品率论坛讨论DFM现状的三位参与者之一。与他共同参加讨论的是Synopsys公司DFM解决方案副总裁Anantha Sethuraman和Photronics公司的CTO Chris Progler。 相似文献
42.
Schulz Laura E.; Bonawitz Elizabeth Baraff; Griffiths Thomas L. 《Canadian Metallurgical Quarterly》2007,43(5):1124
Causal learning requires integrating constraints provided by domain-specific theories with domain-general statistical learning. In order to investigate the interaction between these factors, the authors presented preschoolers with stories pitting their existing theories against statistical evidence. Each child heard 2 stories in which 2 candidate causes co-occurred with an effect. Evidence was presented in the form: AB→E; CA→E; AD→E; and so forth. In 1 story, all variables came from the same domain; in the other, the recurring candidate cause, A, came from a different domain (A was a psychological cause of a biological effect). After receiving this statistical evidence, children were asked to identify the cause of the effect on a new trial. Consistent with the predictions of a Bayesian model, all children were more likely to identify A as the cause within domains than across domains. Whereas 3.5-year-olds learned only from the within-domain evidence, 4- and 5-year-olds learned from the cross-domain evidence and were able to transfer their new expectations about psychosomatic causality to a novel task. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
43.
Joseph L. Keddie Laura J. Norton Edward J. Kramer Emmanuel P. Giannelis 《Journal of the American Ceramic Society》1993,76(10):2534-2538
Neutron reflectometry (NR) was used to directly measure the interface width between a titanium dioxide and a silicon dioxide film deposited by sol-gel processing. In a bilayer heated to 450°C, NR measurements showed that the interface width is 0.8 nm. This width is the same as the roughness of a sol-gel silicon dioxide surface after the same heat treatment, suggesting no interdiffusion or mixing at the bilayer interface. 相似文献
44.
Laura M. Russell Kimberly Y. Donaldson D. P. H. Hasselman Robert Ruh † Jane W. Adams ‡ 《Journal of the American Ceramic Society》1996,79(10):2767-2770
The thermal diffusivity of mullite-ZrO2 -SiCw materials was determined from 25° to 1000°C for composites in which the ZrO2 had different amounts of monoclinic and tetragonal phase, and varying SiC w content. At 25°C the thermal diffusivity of the matrix materials increased with increasing amounts of monoclinic phase, and little or no anisotropy was seen. Composites with SiC w additions showed significant increases in thermal diffusivity and anisotropy as compared with the matrix materials. With increasing temperature, thermal diffusivities of the matrices and their respective composites decreased, and at 1000°C differences were small. Specific heat was determined from 25° to 700°C and thermal conductivity values calculated. Specific heat increased with temperature and was not composition dependent, except for one sample. Thermal conductivity values as a function of temperature followed the same trends as the thermal diffusivity values. 相似文献
45.
46.
Coping with a serious and chronic illness poses unique challenges for individuals in helping professions. What techniques and resources can be used to help the helpers? A narrative framework using the process of externalizing the problem is presented as a potentially useful approach for psychotherapists experiencing a serious illness. The author describes her own experience with lupus and offers recommendations for therapists struggling to balance their professional responsibilities with their own personal needs. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
47.
Kehoe Priscilla; Shoemaker William J.; Triano Laura; Callahan Megan; Rappolt Gabrielle 《Canadian Metallurgical Quarterly》1998,112(1):116
Adult rats that were isolated from the mother and nest for 1 hr per day from Postnatal Day 2 to 9 were studied. Controls consisted of handled littermates as well as separate litters that were never handled. As adults, animals were given either a pharmacological challenge (1.0 or 2.0 mg/kg amphetamine) or an environmental challenge (restraint). Previously isolated animals demonstrated increased activity compared to controls at both drug doses. Similarly, isolated animals manifested exaggerated inhibition of activity after restraint. Previously isolated animals usually did not show differences compared to controls under baseline conditions (saline injection or no restraint). The neuroplastic changes that result from the neonatal experience are long lasting and appear when the system is challenged. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
48.
Laura Menabò Alessandra Sansavini Antonella Brighi Grace Skrzypiec Annalisa Guarini 《Journal of Computer Assisted Learning》2021,37(6):1566-1577
Background: The rapid spread of COVID-19 forced many countries to adopt severe containment measures, transferring all didactic activities into virtual environments. However, the integration of technology in teaching may present difficulties, especially in some countries, such as Italy. Objectives: The present study analyzed how the two main factors of the Technology Acceptance Model (TAM), namely perceived usefulness and perceived ease of use, combined with online teaching self-efficacy, were associated with the intention to use technology to teach. We posited a moderated moderation model in which perceived usefulness represented the main predictor, with self-efficacy and perceived ease of use as moderators of intention to use technology to teach. Method: The model was tested through multiple regressions, using the PROCESS macro on SPSS 26 with a sample of 178 upper secondary school teachers in Italy. Results and conclusions: Regressions showed that each variable significantly predicted the intention to use technology. In addition, a moderation effect of self-efficacy on the perceived usefulness of using technology was found for medium and high-level of perceived ease of use of technology. Implications: The present study provides targeted implications for distance education policy and practice to promote its adoption (or the blended modality) in Italian upper schools. 相似文献
49.
Giuseppina Emanuela Grieco Noemi Brusco Giada Licata Daniela Fignani Caterina Formichi Laura Nigi Guido Sebastiani Francesco Dotta 《International journal of molecular sciences》2021,22(2)
Diabetes mellitus is a group of heterogeneous metabolic disorders characterized by chronic hyperglycaemia mainly due to pancreatic β cell death and/or dysfunction, caused by several types of stress such as glucotoxicity, lipotoxicity and inflammation. Different patho-physiological mechanisms driving β cell response to these stresses are tightly regulated by microRNAs (miRNAs), a class of negative regulators of gene expression, involved in pathogenic mechanisms occurring in diabetes and in its complications. In this review, we aim to shed light on the most important miRNAs regulating the maintenance and the robustness of β cell identity, as well as on those miRNAs involved in the pathogenesis of the two main forms of diabetes mellitus, i.e., type 1 and type 2 diabetes. Additionally, we acknowledge that the understanding of miRNAs-regulated molecular mechanisms is fundamental in order to develop specific and effective strategies based on miRNAs as therapeutic targets, employing innovative molecules. 相似文献
50.
Carmen de Jesús-Gil Lídia Sans-de San Nicols Ester Ruiz-Romeu Marta Ferran Laura Soria-Martínez Irene García-Jimnez Anca Chiriac Josep Manel Casanova-Seuma Josep Manel Fernndez-Armenteros Sherry Owens Antonio Celada Michael D. Howell Ramn María Pujol Luis Francisco Santamaria-Babí 《International journal of molecular sciences》2021,22(4)
Candida albicans (CA) infections have been associated with psoriasis onset or disease flares. However, the integrated immune response against this fungus is still poorly characterized in psoriasis. We studied specific immunoglobulins in plasma and the CA response in cocultures of circulating memory CD45RA− cutaneous lymphocyte antigen (CLA)+/− T cell with autologous epidermal cells from plaque and guttate psoriasis patients (cohort 1, n = 52), and also healthy individuals (n = 17). A complete proteomic profile was also evaluated in plaque psoriasis patients (cohort 2, n = 114) regarding their anti-CA IgA levels. Increased anti-CA IgA and IgG levels are present in the plasma from plaque but not guttate psoriasis compared to healthy controls. CA cellular response is confined to CLA+ T cells and is primarily Th17. The levels of anti-CA IgA are directly associated with CLA+ Th17 response in plaque psoriasis. Proteomic analysis revealed distinct profiles in psoriasis patients with high anti-CA IgA. C-C motif chemokine ligand 18, chitinase-3-like protein 1 and azurocidin were significantly elevated in the plasma from plaque psoriasis patients with high anti-CA levels and severe disease. Our results indicate a mechanism by which Candida albicans exposure can trigger a clinically relevant IL-17 response in psoriasis. Assessing anti-CA IgA levels may be useful in order to evaluate chronic psoriasis patients. 相似文献