On-line evidence for elaborative logical inferences in text.

A model of propositional-logic reasoning proposed by M. D. S. Braine, B. J. Reiser, and B. Rumain (1984) claims that inferences such as "p or q; not p /∴ q" are made spontaneously by readers at the moment both premises are available. This claim is inconsistent with some evidence in the text-processing literature that suggests that only those inferences necessary for textual coherence are made spontaneously. In the present study, participants read stories in which a logical inference was not necessary to maintain textual coherence, and inference making was assessed with on-line probes. Two experiments tested logical forms central to Braine et al's model, and both indicated that participants were making the logical inferences. Two further experiments replicated this result with stories that did not begin with thematic titles. These findings support Braine et al.'s prediction that some propositional-logic inferences are made routinely in texts that do not require them for coherence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Solubilities,densities and electrical conductivities of aqueous copper(I) and copper(II) chlorides in solutions containing other chlorides such as iron,zinc, sodium and hydrogen chlorides

With a view to industrial applications, solubilities, densities and electrical conductivities of aqueous copper(I) and copper(II) chlorides were measured in solutions containing other chlorides like those of iron, zinc, sodium and hydrogen.In these solutions copper(I) chloride shows a behaviour similar to that observed in pure CuClNaClHCl solutions. Increasing the FeCl₂ concentration decreases the solubility of CuCl less than increasing the ZnCl₂ concentrations does. Moreover, increasing total Cl^? concentration increases CuCl solubility if Cl^? is added as FeCl₂ and decreases CuCl solubility if Cl^? is added as ZnCl₂. NaCl solubility remains unchanged by FeCl₂ additions and is increased by ZnCl₂ additions.Copper(II) chloride also shows in these solutions a behaviour similar to that observed in pure CuCl₂NaClHCl solutions. FeCl₃ additions decrease CuCl₂ · 2 H₂O solubility in a more drastic manner than ZnCl₂ additions. However, NaCl additions have a much higher effect.These results can be qualitatively interpreted when taking into account the relative Cl^? donor or acceptor character of the constituent chloride salts of the solution.FeCl₂ additions slightly decrease the electrical conductivity of Cu(I) solutions. However, this can easily be compensated by a slight increase in temperature or in acidity.     

Effect of instructions and modeling on trainees low in interpersonal-communication skills.

Examined the effects of instructions and modeling in the reflection-of-feeling training of individuals low in interpersonal-communication skills. Participants with low scores on R. Carkhuff's Communication Index (25 males and 25 females) were randomly assigned by sex to 1 of the 5 training groups so that there were 5 males and 5 females in each group. After viewing videotaped training material, each participant conducted a 15-min interview with a volunteer "client" and completed the Communication Index a second time. Interviews were scored for frequency of reflection-of-feeling responses and level of empathic communication displayed. Analysis of the reflection-of-feeling data indicated that instructions and instructions-plus-modeling were facilitative procedures. Ratings of written and verbal empathy demonstrated the effectiveness of the 2 combined conditions: instructions-plus-modeling and modeling-plus-instructions. Calculation of correlations among scores on criterion measures revealed a positive correlation between reflection-of-feeling scores and ratings of empathic communication. (20 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Design for a high-speed m.o.s. associative memory

An experimental 64-bit m.o.s. associative memory has been developed from a limit-case design study. Speeds in excess of 50 MHz are reported at a cost per bit that could approach eight times that for a conventional m.o.s. dynamic r.a.m. The design of the basic associative memory cell is described.     

Dietary proanthocyanidins: occurrence, dietary intake, bioavailability, and protection against cardiovascular disease

The French have one of the lowest incidences of coronary heart disease in the Western world despite a diet with a relatively high fat content. This phenomenon that has puzzled researchers worldwide for more than a decade is known as the 'French paradox' and has been linked to the high consumption of red wine in France. Red wine is rich in the complex polyphenols, the proanthocyanidins, and these compounds have recently attracted attention as potential cardiac-protective compounds. The present review summarizes the literature on proanthocyanidins with focus on their chemical structure, the occurrence, the daily intake from foods, the bioavailability and metabolism, and the evidence for a protective effect against cardiovascular diseases.     

Films from oat spelt arabinoxylan plasticized with glycerol and sorbitol

The development of packaging films based on renewable materials is an important and active area of research today. This is the first extensive study focusing on film‐forming properties of an agrobiomass byproduct, namely, oat spelt arabinoxylan. A plasticizer was needed for cohesive film formation, and glycerol and sorbitol were compared. The tensile properties of the films varied with the type and amount of the polyol. With a 10% (w/w) plasticizer content, the films containing glycerol had higher tensile strength than the films containing sorbitol, but with a 40% plasticizer content, the result was the opposite. Sorbitol‐plasticized films retained their tensile properties better than films with glycerol during 5 months of storage. The films were semicrystalline with similar crystallinity indices of 0.20–0.26. The largest crystallites (9.5 nm) were observed in the film with 40% glycerol. The softening of films with 40% (w/w) glycerol started at a significantly lower relative humidity (RH) than that of the corresponding sorbitol‐containing films. The films with sorbitol also had lower water vapor permeability (WVP) than the films with glycerol. The films plasticized with 10% (w/w) sorbitol had a WVP value of 1.1 g mm/(m²·d·kPa) at the RH gradient of 0/54%. The oxygen permeability of films containing 10% (w/w) glycerol or sorbitol was similar: 3 cm³·μm/(m²·d·kPa) at 50–75% RH. A higher plasticizer content resulted in more permeable films. Permeation of sunflower oil through the films was not detected. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009     

Bioengineering of Anti-Inflammatory Natural Products

Inflammatory processes occur as a generic response of the immune system and can be triggered by various factors, such as infection with pathogenic microorganisms or damaged tissue. Due to the complexity of the inflammation process and its role in common diseases like asthma, cancer, skin disorders or Alzheimer's disease, anti-inflammatory drugs are of high pharmaceutical interest. Nature is a rich source for compounds with anti-inflammatory properties. Several studies have focused on the structural optimization of natural products to improve their pharmacological properties. As derivatization through total synthesis is often laborious with low yields and limited stereoselectivity, the use of biosynthetic, enzyme-driven reactions is an attractive alternative for synthesizing and modifying complex bioactive molecules. In this minireview, we present an outline of the biotechnological methods used to derivatize anti-inflammatory natural products, including precursor-directed biosynthesis, mutasynthesis, combinatorial biosynthesis, as well as whole-cell and in vitro biotransformation.     

Association between patient psychosocial characteristics and receipt of in‐center nocturnal hemodialysis among prevalent dialysis patients

Introduction: Compared to traditional in‐center hemodialysis (HD), in‐center nocturnal dialysis (INHD) is characterized by longer sessions and nighttime administration, which may lead to better outcomes for some patients. Given the importance of patient choice in the decision to initiate INHD, we explored associations between patients’ psychosocial characteristics and their receipt of INHD. Methods: Among hemodialysis patients at a medium‐sized dialysis organization, we identified INHD patients as those for whom ≥80% of dialysis sessions were INHD sessions—starting at 6:30 pm or later and lasting ≥5 hours—over the 3 months (≥20 sessions total) after their first INHD session. We extracted dialysis session data from electronic medical records and psychosocial data from social worker assessments. We tested associations of patients’ psychosocial characteristics—as well as demographic and clinical characteristics—with INHD receipt among all hemodialysis patients (INHD and HD) in bivariate analyses and multivariable logistic regression models. Findings: Among 759 patients with complete data, we identified 47 (6.2%) as INHD patients. On average, these patients were more likely than HD patients to be employed (full‐time 10.6% vs. 5.2%; part‐time 17.0% vs. 4.2%; P < 0.001), and they were significantly less likely to require ambulatory assistance (14.9% vs. 39.6%, P < 0.001). In multivariable regressions, we found that part‐time employment (versus being unemployed) was associated with a 7.1 percentage‐point higher likelihood of being an INHD patient (P = 0.01), and the negative association with ambulatory assistance needs approached statistical significance (P = 0.056). No other psychosocial factors included in this main regression analysis were statistically significantly associated with INHD patient status. Discussion: Researchers comparing the outcomes of patients undergoing INHD versus other treatment modalities will need to account for differences in employment status—and other factors like requiring ambulatory assistance and age which may predict the ability to work—between INHD users and comparison patients to avoid bias in estimates.