Comparison of new activation functions in neural network for forecasting financial time series

In artificial neural networks (ANNs), the activation function most used in practice are the logistic sigmoid function and the hyperbolic tangent function. The activation functions used in ANNs have been said to play an important role in the convergence of the learning algorithms. In this paper, we evaluate the use of different activation functions and suggest the use of three new simple functions, complementary log-log, probit and log-log, as activation functions in order to improve the performance of neural networks. Financial time series were used to evaluate the performance of ANNs models using these new activation functions and to compare their performance with some activation functions existing in the literature. This evaluation is performed through two learning algorithms: conjugate gradient backpropagation with Fletcher–Reeves updates and Levenberg–Marquardt.     

Audio watermarking scheme based on embedding strategy in low frequency components with a binary image

With the recent development of information technology and computer network, digital format of data has become more and more popular. However, a major problem faced by digital data providers and owners is protecting data from unauthorized copying and distribution. As a solution to the problem, digital watermark technology is now attracting attention as new method of protection against said unauthorized copying and distribution. The aim of the digital audio watermarking is to take prespecified data that carries certain information and hide it within the audio stream such that it is not audible to the human ear (i.e., transparent) but at the same time renders the file more resistant to removal (i.e., robust). In this paper, we propose a new method for embedding digital watermarks into audio signals in low frequency components, which method mitigates these and other related shortcomings. The proposed method uses the wavelet transform constructed by lifting-based wavelet transform (LBWT) in order to provide a fast implementation between watermark embedding and extraction parts. In the first stage of the proposed method, the original audio host signal is converted to a wavelet domain using LBWT. The signal is thus decomposed into low and high frequency components. Approximation coefficients correspond to low frequency components of the signal. Next, the watermark generated by pseudorandom numbers is embedded into wavelet approximation coefficients of the segmented host audio signal depending on the binary value of the binary image. The reason for embedding the watermark in the low frequency components is that these components' energy is greater than that of high frequency components in such a way that the watermark is inaudible; therefore, it should not alter the audible content and should not be easy to remove. The proposed method uses a binary image to decide whether or not the watermark generated by pseudorandom numbers is embedded in the audio host signal. To evaluate the performance of the proposed audio watermarking method, subjective and objective quality tests including bit error rate (BER) and signal-to-noise ratio (SNR) are conducted. The tests' results show that the proposed method yields a high recovery rate after attacks by commonly used audio data manipulations such as low-pass filtering, requantization, resampling and MP3 compression.     

Efficient solution techniques for the integrated coverage, sink location and routing problem in wireless sensor networks

Sensors are tiny electronic devices having limited battery energy and capability for sensing, data processing and communicating. They can collectively behave to provide an effective wireless network that monitors a region and transmits the collected information to gateway nodes called sinks. Most of the applications require the operation of the network for long periods of times, which makes the efficient management of the available energy resources an important concern. There are three major issues in the design of sensor networks: sensor deployment or the coverage of the sensing area, sink location, and data routing. In this work, we consider these three design problems within a unified framework and develop two mixed-integer linear programming formulations. They are difficult to solve exactly. However, it is possible to compute good feasible solutions of the sink location and routing problems easily, when the sensors are deployed and their locations in the sensor field become known. Therefore, we propose a tabu search heuristic that tries to identify the best sensor locations satisfying the coverage requirements. The objective value corresponding to each set of sensor locations is calculated by solving the sink location and routing problem. Computational tests carried out on randomly generated test instances indicate that the proposed hybrid approach is both accurate and efficient.     

The loyal member effect: On the preference for ingroup members who engage in exclusive relations with the ingroup.

The goal of this article was to investigate an indirect form of intergroup differentiation in children in the context of racial attitudes: the preference for ingroup members who interact positively with other ingroup members rather than with outgroup members. Study 1 confirmed this general hypothesis with preschool and 1st-grade children, demonstrating that respondents preferred the ingroup member who played only with other ingroup members, evaluated this child more positively, and felt more similar to him or her. Studies 2 and 3 tested the boundary conditions of the phenomenon. Study 4 analyzed developmental changes demonstrating that the effect is no longer observed among 9- to 11-year-old children. Overall, these studies suggest that engaging in positive interactions with the outgroup might have its costs in terms of a relative devaluation and rejection by one's peers. Results are discussed by stressing the importance of intragroup processes for the regulation of intergroup relations among very young children. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Evaluation of sequential thallium and gallium scans of the chest in AIDS patients

With decreasing incidence of pneumocystis carinii pneumonia (PCP) in AIDS as a result of prophylactic regimens, there is a higher incidence of tuberculosis (TB), mycobacterium avii complex (MAC), kaposi sarcoma and malignant lymphoma. There is a need for differentiating these various pathological entities. The purpose of this study was for a retrospective evaluation of sequential thallium and gallium scans in AIDS patients for differentiating intrathoracic kaposi sarcoma from malignant lymphoma and opportunistic infections. METHODS: A total of 181 patients had both studies completed between March 1992 and May 1994. The final diagnosis was verified only in 83 patients. Results were correlated with the CD4 counts, bronchoscopic and chest radiograph findings. RESULTS: In patients with pulmonary kaposi sarcoma and no opportunistic infections (19 patients), a thallium-positive, gallium-negative pattern was detected in 17 patients with a sensitivity of 89%. In the presence of kaposi sarcoma plus opportunistic infections, this pattern was only detected in 7 of 19 patients (sensitivity dropped to 37%). In 45 patients with opportunistic infections and no kaposi sarcoma, only two false-positive findings were found in patients with cytomegalic virus pneumonia for a specificity of 96%. For the whole group of 83 patients, sensitivity was 63%; specificity 95%; positive predictive value 92%; accuracy 81%; and negative predictive value 75%. CONCLUSION: A thallium-positive, gallium-negative pattern in AIDS patients has a high specificity for the diagnosis of kaposi sarcoma, however, the sensitivity dropped from 89% to 37% in the presence of opportunistic infections.     

Causes of scent marking in female golden hamsters (Mesocricetus auratus): Specific signals or classes of information?

Odor-elicited scent marking is common among mammals, but the proximate causes of marking are not well understood. Scent marking by female hamsters in response to 8 different male odors was investigated. Two odors (flank, mouth) increased flank marking and 2 (flank, rump) increased vaginal marking; in the latter case the effects of flank and rump odors were additive. Two odors (feces, urine) decreased flank marking but did not affect vaginal marking; other odors (foot, ear, ano-genital) had no influence on either scent-marking behavior. Results show that scent marking by females is influenced by a limited number of male odors, suggesting specific effects of particular odors. Classes of information (such as sexual identity) were not relevant causes of scent marking, as some odors containing such information were effective but others were not. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

99mTc-citrate versus 67Ga-citrate for the scintigraphic visualization of inflammatory lesions

Citric acid was labeled with 99mTc with an efficiency of > 99%. The biodistribution of 99mTc-citrate was studied in mice with turpentine-induced abscesses in comparison to 67Ga-citrate. The max. abscess/muscle concentration ratios were 4.61 +/- 1.92 (3 h) for 99mTc-citrate and 4.76 +/- 2.04 (4 h) for 67Ga-citrate. Arthritis was induced in 10 rabbits by intra-articular injection of ovalbumin Scintigrams obtained 4 days later and at 3 h post-injection of 99mTc-citrate showed increased activity involving the synovium. The max. arthritic/contralateral knee ratio was 3.19 +/- 1.29 (3 h) and 6.47 +/- 3.71 (24 h) for 99mTc- and 67Ga-citrate, respectively. The blood clearance curve of 99mTc-citrate in rabbits was biexponential with a fast (T1/2 = 36 min) and a slow (T1/2 = 18 h) component, compared to mono-exponential clearance of 67Ga-citrate (T1/2 = 23 h). In 10 patients with rheumatoid arthritis whole-body scintigrams and spot images of involved joints indicated localization of the tracer in inflamed tissues. The mean target-to-soft tissue ratios were 3.04 +/- 0.81 and 4.95 +/- 2.56 for 99mTc-citrate and 99mTc-MDP, respectively. Renal clearance of radioactivity was evident from the scintigrams. Our results demonstrated that 99mTc-citrate is effective as a radiopharmaceutical for the visualization of inflammatory lesions and may be preferred to 67Ga-citrate due to the ideal physical characteristics of the radionuclide, easy preparation, low cost, early accumulation and the preference for the renal route of excretion.     

An adaptive tabu search approach for buffer allocation problem in unreliable non-homogenous production lines

The buffer allocation problem, i.e. how much buffer storage to allow and where to place it within the line, is an important research issue in designing production lines. In this study, a novel adaptive tabu search approach is proposed for solving buffer allocation problem in unreliable and non-homogeneous production lines. The objective is to maximize the throughput of the line, which is constrained by the capacity of each buffer space and also the total buffer capacity to allocate to these spaces. Besides proposing a new strategy to tune the parameters of tabu search adaptively during the search, an experimental study is carried out to select an intelligent initial solution scheme among three alternatives so as to decrease the search effort to obtain the best solutions. The performance of the proposed approach is evaluated by computational tests and very promising results are obtained.     

Automated evaluation of physical therapy exercises using multi-template dynamic time warping on wearable sensor signals

We develop an autonomous system to detect and evaluate physical therapy exercises using wearable motion sensors. We propose the multi-template multi-match dynamic time warping (MTMM-DTW) algorithm as a natural extension of DTW to detect multiple occurrences of more than one exercise type in the recording of a physical therapy session. While allowing some distortion (warping) in time, the algorithm provides a quantitative measure of similarity between an exercise execution and previously recorded templates, based on DTW distance. It can detect and classify the exercise types, and count and evaluate the exercises as correctly/incorrectly performed, identifying the error type, if any. To evaluate the algorithm's performance, we record a data set consisting of one reference template and 10 test executions of three execution types of eight exercises performed by five subjects. We thus record a total of 120 and 1200 exercise executions in the reference and test sets, respectively. The test sequences also contain idle time intervals. The accuracy of the proposed algorithm is 93.46% for exercise classification only and 88.65% for simultaneous exercise and execution type classification. The algorithm misses 8.58% of the exercise executions and demonstrates a false alarm rate of 4.91%, caused by some idle time intervals being incorrectly recognized as exercise executions. To test the robustness of the system to unknown exercises, we employ leave-one-exercise-out cross validation. This results in a false alarm rate lower than 1%, demonstrating the robustness of the system to unknown movements. The proposed system can be used for assessing the effectiveness of a physical therapy session and for providing feedback to the patient.     

19F MRI Nanotheranostics for Cancer Management: Progress and Prospects

Fluorine magnetic resonance imaging (¹⁹F MRI) is a promising imaging technique for cancer diagnosis because of its excellent soft tissue resolution and deep tissue penetration, as well as the inherent high natural abundance, almost no endogenous interference, quantitative analysis, and wide chemical shift range of the ¹⁹F nucleus. In recent years, scientists have synthesized various ¹⁹F MRI contrast agents. By further integrating a wide variety of nanomaterials and cutting-edge construction strategies, magnetically equivalent ¹⁹F atoms are super-loaded and maintain satisfactory relaxation efficiency to obtain high-intensity ¹⁹F MRI signals. In this review, the nuclear magnetic resonance principle underlying ¹⁹F MRI is first described. Then, the construction and performance of various fluorinated contrast agents are summarized. Finally, challenges and future prospects regarding the clinical translation of ¹⁹F MRI nanoprobes are considered. This review will provide strategic guidance and panoramic expectations for designing new cancer theranostic regimens and realizing their clinical translation.