基于人工免疫的网络安全态势评估模型

本文将人工免疫原理应用到网络安全态势评估的研究中.通过对入侵检测模型中有关自体、非自体、抗原的形式化描述,建立了抗体细胞的演化机制、动态免疫记忆、免疫监视等免疫机制.依据人体免疫系统抗体浓度的变化与病原体入侵强度的对应关系,建立了网络安全态势实时定量计算模型.     

财务状况变动表的运用──以营运资金为基础的财务状况变动表的分析

根据企业会计准则要求企业应编报财务状况变动表,但该表在我国运用尚属首次,人们对它的认识还很浮浅。现以该表的编报基础营运资金为对象,分析财务状况变动表的内容及表中列示资料的作用,力图达到能运用该表资料以分析企业财务状况变动情况之目的。     

Analysis of light propagation characteristic in the aero-optic flow field of cone-headed vehicle with side window

Aero-optic imaging deviation research is carried out for infrared-guided vehicle with cone-head side window, with a focus on the propagation characteristics of light in an aero-optic flow field. When the light entering the aero-optic flow field from the free-stream should be close to the normal, numerous data indicate that the light is refracted away from the normal. This paper divides the aero-optic flow field into two parts and uses the gas density distribution in the aero-optic flow field to ...     

SAdaBoundNc: an adaptive subgradient online learning algorithm with logarithmic regret bounds

Neural Computing and Applications - Adaptive (sub)gradient methods have received wide applications such as the training of deep networks. The square-root regret bounds are achieved in convex...     

Macrophage Membrane-Coated Nanoparticles Sensitize Glioblastoma to Radiation by Suppressing Proneural–Mesenchymal Transformation in Glioma Stem Cells

Radiotherapy is identified as a crucial treatment for patients with glioblastoma, but recurrence is inevitable. The efficacy of radiotherapy is severely hampered partially due to the tumor evolution. Growing evidence suggests that proneural glioma stem cells can acquire mesenchymal features coupled with increased radioresistance. Thus, a better understanding of mechanisms underlying tumor subclonal evolution may develop new strategies. Herein, data highlighting a positive correlation between the accumulation of macrophage in the glioblastoma microenvironment after irradiation and mesenchymal transdifferentiation in glioblastoma are presented. Mechanistically, elevated production of inflammatory cytokines released by macrophages promotes mesenchymal transition in an NF-κB-dependent manner. Hence, rationally designed macrophage membrane-coated porous mesoporous silica nanoparticles (MMNs) in which therapeutic anti-NF-κB peptides are loaded for enhancing radiotherapy of glioblastoma are constructed. The combination of MMNs and fractionated irradiation results in the blockage of tumor evolution and therapy resistance in glioblastoma-bearing mice. Intriguingly, the macrophage invasion across the blood-brain barrier is inhibited competitively by MMNs, suggesting that these nanoparticles can fundamentally halt the evolution of radioresistant clones. Taken together, the biomimetic MMNs represent a promising strategy that prevents mesenchymal transition and improves therapeutic response to irradiation as well as overall survival in patients with glioblastoma.     

Proximity-Induced Fully Ferromagnetic Order with Eightfold Magnetic Anisotropy in Heavy Transition Metal Oxide CaRuO3

Ferromagnetic materials with a strong spin-orbit coupling (SOC) have attracted much attention in recent years because of their exotic properties and potential applications in energy-efficient spintronics. However, such materials are scarce in nature. Here, a proximity-induced paramagnetic to ferromagnetic transition for the heavy transition metal oxide CaRuO₃ in (001)-(LaMnO₃/CaRuO₃) superlattices is reported. Anomalous Hall effect is observed in the temperature range up to 180 K. Maximal anomalous Hall conductivity and anomalous Hall angle are as large as ∼15 Ω⁻¹ cm⁻¹ and ∼0.93%, respectively, by one to two orders of magnitude larger than those of the typical 3d ferromagnetic oxides such as La_0.67Sr_0.33MnO₃. Density functional theory calculations indicate the existence of avoid band crossings in the electronic band structure of the ferromagnetic CRO layer, which enhances Berry curvature thus strong anomalous Hall effects. Further evidences from polarized neutron reflectometry show that the CaRuO₃ layers are in a fully ferromagnetic state (∼0.8 μ_B/Ru), in sharp contrast to the proximity-induced canted antiferromagnetic state in 5d oxides SrIrO₃ and CaIrO₃ (∼0.1 μ_B/Ir). More than that, the magnetic anisotropy of the (001)-(LaMnO₃/CaRuO₃) superlattices is eightfold symmetric, showing potential applications in the technology of multistate data storage.     

Novel,liquid crystal formula to overcome LTPS LCD image sticking without adjustment of gamma code,optical, VHR and IS evaluation

In this article, novel n-FFS liquid crystal material from Slichem was used in order to elevate the anti-backlight long aging effect; a trace amount of free radical trap HALS-like additive was added, the principle of which can be expressed via Denisov cycle, confirmed by measuring the temporal VHR changes in test cells; three different resolution (FHD ~ QHD) models paired with N19 and N21 were selected for testing by comparing the actual panel. It is verified that the optimized material greatly improves the image sticking performance of the panel and keeping optical performance.     

DDNSR: a dual-input degradation network for real-world super-resolution

Pattern Analysis and Applications - Recently, Real-World Super-Resolution has become one of the most popular research fields in the scope of Single Image Super-Resolution, as it focuses on...     

基于网源协同的300MW 机组负荷快调及综合调频技术研究

大力发展新能源和大规模外电入鲁是山东实现新旧动能转换、推动经济快速平稳发展的关键之举,截至017年,新能源发电量和外电入鲁电量已占全省发电量的40.98％,到2018年风电和光电装机容量已达到千万千瓦 级别.但是,新能源受天气因素制约,一直处于随机波动状态,实时干扰电网频率,直接影响人民生活和工业生产, 甚至会产生弃风弃光事件;而特高压直流输电线路一旦出现故障,就会产生巨大供电缺口,导致电网频率突降,极有 可能引发大面积停电事故,造成重大经济损失和不良社会影响.因此,火电机组必须具备良好的一次调频和 AGC等 涉网性能,才能弥补新能源发电量波动和外电入鲁故障造成的频率波动,才能破解新能源消纳难题,为准确应对外电 故障提供数据支撑。     

Design of a 2-DOF-PID controller using an improved sine–cosine algorithm for load frequency control of a three-area system with nonlinearities

This paper proposes an improved sine–cosine algorithm (ISCA) based 2-DOF-PID controller for load frequency control. A three-area test system is built for study, while some physical constraints (nonlinearities) are considered for the investigation of a realistic power system. The proposed method is used as the parameter optimizer of the LFC controller in different scenarios. The 2-DOF-PID controllers are used because of their capability of fast disturbance rejection without significant increase of overshoot in set-point tracking. The 2-DOF-PID controllers’ efficacy is observed by examining the responses with the outcomes obtained with PID and FOPID controllers. The simulation results with the suggested scheme are correlated with some of the existing algorithms, such as SCA, SSA, ALO, and PSO in three different scenarios, i.e., a disturbance in two areas, in three areas, and in the presence of physical constraints. In addition, the study is extended to a four-area power system. Statistical analysis is performed using the Wilcoxon Sign Rank Test (WSRT) on 20 independent runs. This confirms the supremacy of the proposed method.