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One of the most important targets in vehicle design is passive safety; this more and more stringent requirement leads the designer towards new vehicle architectural solutions and innovative materials. Aluminium foams are a new class of materials with promise an improvement of vehicle crashworthiness, combining the properties derived from the cellular structure, in particular the lightness, with the typical behavior of metals.  相似文献   
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The spacers for the Gas Insulated Transmission Line for the ITER neutral beam injector will be designed to withstand the operating voltage of 1 MV dc. Electric charging processes of the spacer surface are then expected to play an important role in the final electric field distribution. Aim of the paper is to investigate the effects of the different conductivity properties of the SF6-Spacer insulating structures on the surface charge set-up, and to identify a procedure to minimize this charge. Based on the most updated literature, the paper presents and discusses the results of two newly developed simulation tools: the first consisting of a quasi-static non linear model for epoxy spacer based on finite element method code ANSYS?, the other consisting of a spacer profile optimization package, whose kernel is based on a genetic algorithm. The numerical tools have been applied to post and disk spacer models of the gas insulated line; in particular, the optimization package has been used on the disk spacer, and the comparison between un-optimized and optimized spacer in terms of electric charge accumulated are presented and discussed.  相似文献   
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Membranes of cellulose acetate from sugarcane bagasse (CA), as well as blends of this cellulose acetate and polystyrene from plastic cups (CA/PS) were produced by casting utilizing dichloromethane as solvent at the concentration 12% w/w. The membranes were characterized regarding ion diffusion by dialysis and properties of pure water permeation rate, PEG rejection (utilizing an aqueous solution 1% w/v of polyethylene glycol (PEG), 45 and 80 kDa). Thermal characterization by thermogravimetric analysis and differential scanning calorimetry were also performed. The morphology of the membranes' cross‐sections was evaluated by scanning electron microscopy. The experiment of ion diffusion by dialysis showed that the ion diffusion coefficient of CA membrane is comparable to that found in the literature for membranes of commercial cellulose triacetate, 8.47 × 10?8 cm2 s?1, while the ion diffusion coefficient of blends decreased as PS was added to the system. Regarding transport driven by pressure, CA membrane presented low rejection of PEG 80 kDa. These results showed that CA membrane could be used in a range of application comprehending the process of ultrafiltration or microfiltration. POLYM. ENG. SCI., 2008. © 2008 Society of Plastics Engineers.  相似文献   
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β2‐Microglobulin (β2‐m) is a protein responsible for a severe complication of long‐term hemodialysis, known as dialysis‐related amyloidosis, in which initial β2‐m misfolding leads to amyloid fibril deposition, mainly in the skeletal tissue. Whereas much attention is paid to understanding the complex mechanism of amyloid formation, the evaluation of small molecules that may bind β2‐m and possibly inhibit the aggregation process is still largely unexplored mainly because the protein lacks a specific active site. Based on our previous findings, we selected a pilot set of sulfonated molecules that are known to either bind or not to the protein, including binders that are anti‐amyloidogenic. We show how a complementary approach, using high‐resolution mass spectrometry and in silico studies, can offer rapid and precise information on affinity, as well as insight into the structural requisites that favour or disfavour the inhibitory activity. Overall, this approach can be used for predictive purposes and for a rapid screening of fibrillogenesis inhibitors.  相似文献   
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The energy stored in the 1 MV ITER Neutral Beam Injector power supply system will exceed by far the energy stored in the existing largest NB Injectors; as a consequence, the limitation of the grid breakdown effects–grids damage and Electro Magnetic Interference emission–are critical issues. In the present ITER NBI reference design the mitigation system is based on the concept of the concentrated core snubber which, due to the large amount of stored energy, is a huge component. Furthermore, in the NBI a relatively large part of HV capacitance to ground remains downstream the core snubber, so neither the arc peak current nor the high-frequency oscillations can be effectively limited. Moreover, the concentrated core snubber is ineffective in limiting the voltage reversal caused by internal insulation fault, increasing the risk of cascade failures in components like HV bushing and transmission line. The paper proposes an alternative approach to limit the grid breakdown effects, based on the concepts of Damper Resistor- substituting the direct connection to ground of the zero-potential accelerating grid – and of Distributed Core Snubber (DCS) – installed along the whole length of the transmission lines. The DCS concept has been subjected also to experimental validation by a small scale setup supported by electrical modelling.  相似文献   
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The failure mode and effects analysis (FMEA) is a widely used analytical technique that helps in identifying and reducing the risks of failure in a system, component or process.The application of a systematic method like the FMEA was deemed necessary and adequate to support the design process of the ITER NBI (neutral beam injector). The approach adopted was to develop a FMEA at a general “system level”, focusing the study on the main functions of the system and ensuring that all the interfaces and interactions are covered among the various subsystems. The FMEA was extended to the whole NBI system taking into account the present design status. The FMEA procedure will be then applied to the detailed design phase at the component level, in particular to identify (or define) the ITER Class of Risk.Several important failure modes were evidenced, and estimates of subsystems and components reliability are now available. FMEA procedure resulted essential to identify and confirm the diagnostic systems required for protection and control, and the outcome of this analysis will represent the baseline document for the design of the NBI and NBTF integrated protection system.In the paper, rationale and background of the FMEA for ITER NBI are presented, methods employed are described and most interesting results are reported and discussed.  相似文献   
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The 100 keV Ion Source Test facility – Source for the Production of Ions of Deuterium Extracted from RF plasma (SPIDER) – is aimed to test the full scale prototype of the Ion Source for the ITER 1 MeV Neutral Beam Injector (NBI). The SPIDER facility requires the construction of a High Voltage Deck (HVD) and of a High Voltage Transmission Line (TL) respectively to host the Ion Source Power Supplies system polarized at 100 kV and to carry the power and signal conductors to the beam accelerator.In already existing NBI systems with beam energy above 100 keV, the TL is realized with the SF6 Gas Insulated Line technology. In the SPIDER TL case, the presence of a large inner conductor (half meter diameter), would make the pressurized TL a complex and costly component; therefore a free air insulated solution has been proposed. The paper focuses on the design of this TL, which has to host inside the complex high potential (100 kV) inner electrode a number of power and measuring conductors and has to minimize the Electro Magnetic Interferences (EMI) produced by the frequent grids breakdowns.Finite Element (FE) analyses have been performed to verify the configuration from the electrostatic point of view, to evaluate EMI screening effectiveness and to assess the impact of the relatively high thermal dissipation of power conductors located inside the high potential electrode. Moreover, an experimental test campaign has been carried out on a TL mockup to validate the TL electrostatic configuration under DC voltage. Finally, the paper reports on the status of procurement activities for the Transmission Line.  相似文献   
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