Improved protein resistance of silicone hydrogels by grafting short peptides for ophthalmological application

A simple and facile approach to impart the antifouling properties of silicone hydrogels was developed in this report. Short peptides were first tethered to silicone hydrogels through terminal amino group-induced epoxy ring-opening click reaction. The modified silicone hydrogels have improved hydrophilicity and protein adsorption resistance because of the formation of zwitterionic structure of the grafted peptides. Furthermore, glycylglycine and diglycyl glycine-modified silicone hydrogel contact lenses were fabricated. They exhibited favorable antifouling property and no damage to rabbits’ eyes after continuous wearing. The short peptide modified silicone hydrogel contact lenses have potential application in ophthalmology.     

A novel inverse modeling control for piezo positioning stage

Journal of Mechanical Science and Technology - This paper focuses on the application of a novel inverse nonlinear autoregressive with exogenous input (NARX) structure and a fuzzy inference system...     

A Molecular Dynamics and Lattice Boltzmann Multiscale Simulation for Dense Fluid Flows

A molecular dynamics (MD)-lattice Boltzmann (LB) hybrid scheme has been adopted to simulate dense fluid flows. Based on the domain decomposition method and the Schwarz alternating scheme, the “Maxwell Demon” approach is used to impose boundary conditions from the continuum to the atomistic region, while the “reconstruction operator” is implemented to construct the single-particle distribution function of the LB method from the results of the MD simulation. Couette flows and the flow of a dense fluid argon around a carbon nanotube (CNT) are solved to validate the hybrid method. When the mesh of the LB domain is refined and the size of corresponding sampling cells of the MD domain is reduced, the fluctuations of the results between two successive iterations of the hybrid method become more severe, although the results get closer to the MD reference solutions. To decrease the fluctuation due to the mesh refinement, a new weighting function is proposed for the sampling of MD simulation results. Numerical practice demonstrates its feasibility.     

院校科研信息管理系统的设计与实现

随着院校技术研发投入的不断加大以及科研管理的规范化和制度化,建立一套适用于大学科研管理工作的科研管理信息平台,已经成为科研部各处室、大学各院系和相关部门较为迫切的需求。以大学科研部的工作实际为背景,应用现代计算机和数据库技术,严格按照软件工程的方法,开发了Client/Server结构的院校科研信息管理系统。该系统已经投入使用,运行情况良好,性能指标满足设计要求。     

苯加氢烷基化制环己基苯催化剂的制备与工艺条件的考察

采用等体积浸渍法制备了Ni-Cu/Hβ双功能催化剂,采用XRD、N2吸附-脱附、TEM和NH3-TPD方法对催化剂进行了表征,并将其用于催化苯加氢烷基化制备环己基苯的反应,考察了催化剂的制备条件(Ni负载量、Ni和Cu的来源、助催化剂的种类)和反应条件(反应时间、反应温度、氢气压力、催化剂用量)对反应的影响。实验结果表明,适宜的催化剂制备条件和反应条件为:Ni和Cu的来源分别为乙酸镍和硝酸铜、负载量分别为4%(w)和0.2%(w);反应温度210℃、氢气压力2 MPa、反应时间1 h、催化剂用量5%(w)(基于苯的质量)。在此条件下,苯的转化率可达57.74%,环己基苯的选择性可达71.38%。催化剂的金属活性位和酸性是苯加氢烷基化的关键因素。     

建筑施工安全管理探究

伴随着建筑业市场的繁荣,建筑业给施工本身带来相应的问题。建筑施工安全的管理就是建筑业面临的问题,建筑施工的安全是建筑施工有效顺利进行的前提和保障,充分体现了管理者的能力。本文将就建筑施工安全管理进行探究,提出浅见。     

国家网球馆“钻石球场”开合屋盖结构设计

国家网球馆是一座带有开合屋盖的现代大型体育场馆。在设计中提出开合屋盖的性能指标与设计荷载取值方法。屋盖开合状态对风荷载敏感,需要通过风洞试验确定风压分布与脉动特性。活动屋盖运行过程中台车反力不断变化,需要通过对其移动过程分析,找出最不利位置。研究了各种开合位置的结构动力特性,采用时程法与振型分解反应谱法分析活动屋盖在多遇地震作用下的响应。此外,在活动屋盖移动对固定屋盖轨道桁架变形影响分析的基础上,提出一种适用于圆形平面带矩形洞口结构的起拱曲面方程。     

Effect of natural aging on microstructure and mechanical properties of friction stir welded 7050-T7451 joints

The microstructure and mechanical properties of friction stir welded 2.5 mm 7050-77451 aluminum alloy natural aging 72 h and 17 520 h were investigated,respectively.The uniaxial tensile test showed that yield strength,tensile strength and elongation of the joints 17 520 h natural aging were about 20%,12%and 24%higher than those joints natural aging72 h.Hardness profile of natural aging 17 520 h joint witnessed significant enhancement in nugget zone,compared with 72 h natural aging.Differential scanning calorimetry(DSC) and transmission electron microscopy(TEM) test revealed that more Guinier-Preston zone,η' and η phase emerged in nugget zone as natural aging duration increased,high density of dislocation located within grain boundary in nugget zone of joints natural aging 72 h.It is concluded that natural aging was feasible to enhance strength and plasticity of FSW joints simultaneously.     

低应变瞬态荷载作用下基桩动力响应解析解

目前广泛采用的基桩低应变检测问题的理论基础是基于平截面假定的一维应力波理论。而实际上,锤击产生的应力波是三维应力波,不仅沿桩身纵向传播,还沿径向传播,对于基桩低应变检测问题平截面假定实际上是不成立的。此时,一维纵波传播问题转换为应力波沿三维柱体传播问题。文章从基桩三维理论出发,忽略桩土径向位移,考虑桩体中应力波沿纵向和径向传播与桩土的相互作用,建立三维条件下桩土系统瞬态振动计算模型,推导得到低应变瞬态荷载作用下基桩三维动力响应的解析解,以期为基桩低应变检测提供新的理论指导。